Åke Engström

Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen (2005)

Bajtner, Estelle, Nandakumar, Kutty S, Engström, Åke, Holmdahl, Rikard

Abstract Antibodies against type II collagen (CII) are important in the development of collagen-induced arthritis (CIA) and possibly also in rheumatoid arthritis. We have determined the fine...

Structure and evolution of the heavy chain from rat immunoglobulin E (1982)

Hellman, Lars, Pettersson, Ulf, Engström, Åke, Karlsson, Torbjörn, Bennich, Hans

The nucleotide sequence of the rat ϵ-chain mRNA has been determined by sequencing cloned cDNA copies of the mRNA. The established sequence covers the coding region, the 3′-non coding region...

Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen

Bajtner, Estelle, Nandakumar, Kutty S, Engström, Åke, Holmdahl, Rikard

Antibodies against type II collagen (CII) are important in the development of collagen-induced arthritis (CIA) and possibly also in rheumatoid arthritis. We have determined the fine specificity and...

Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity

Zavialov, Andrey V., Engström, Åke

Two distinct isoenzymes of ADA (adenosine deaminase), ADA1 and ADA2, have been found in humans. Inherited mutations in ADA1 result in SCID (severe combined immunodeficiency). This observation has led...

Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity

Zavialov, Andrey V., Engström, Åke

Two distinct isoenzymes of ADA (adenosine deaminase), ADA1 and ADA2, have been found in humans. Inherited mutations in ADA1 result in SCID (severe combined immunodeficiency). This observation has led...

Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen

Bajtner, Estelle, Nandakumar, Kutty S, Engström, Åke, Holmdahl, Rikard

Antibodies against type II collagen (CII) are important in the development of collagen-induced arthritis (CIA) and possibly also in rheumatoid arthritis. We have determined the fine specificity and...

Reassessing a sparse energetic network within a single protein domain

Chi, Celestine N., Elfström, Lisa, Shi, Yao, Snäll, Tord, Engström, Åke, Jemth, Per

Understanding the molecular principles that govern allosteric communication is an important goal in protein science. One way allostery could be transmitted is via sparse energetic networks of...

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis

Uysal, Hüseyin, Bockermann, Robert, Nandakumar, Kutty S., Sehnert, Bettina, Bajtner, Estelle, Engström, Åke, ...

Antibodies to citrulline-modified proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear. To obtain insight into...