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Effect of Low-Dose Antigen Exposure on Development of Immunity to Helicobacter pylori Infection in Mice

Abstract
The effect of low-dose antigen exposure on the development of immunity to Helicobacter pylori infection was studied in outbred mice. Animals that were primed with a subinfectious number of H. pylori bacteria exhibited significantly lower bacterial loads after challenge with an infectious dose of pathogen (versus controls, P < 0.05).

Publication details
Download http://www.pubmedcentral.gov/articlerender.fcgi?artid=98618
Publisher American Society for Microbiology
Repository PubMed Central (PMC3 - NLM DTD) (United States)
Keywords Microbial Immunity and Vaccines
Type Text
Language Englisch