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Identification and Characterization of the gerH Operon of Bacillus anthracis Endospores: a Differential Role for Purine Nucleosides in Germination

Abstract
We identified a tri-cistronic operon, gerH, in Bacillus anthracis that is important for endospore germination triggered by two distinct germination response pathways termed inosine-His and purine-Ala. Together, the two pathways allow B. anthracis endospores a broader recognition of purines and amino acids that may be important for host-mediated germination.

Publication details
Download http://www.pubmedcentral.gov/articlerender.fcgi?artid=142867
Publisher American Society for Microbiology
Repository PubMed Central (PMC3 - NLM DTD) (United States)
Keywords Molecular Biology of Pathogens
Type Text
Language Englisch