| Production of cyclochlorotine and a new metabolite, simatoxin, by Penicillium islandicum Sopp. | |||||||||||
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| Production of the hepatotoxin cyclochlorotine by Penicillium islandicum was studied under a variety of fermentation conditions. The best system for production was agitated red wheat. A thin-layer chromatographic method was developed for the detection of this cyclic polypeptide. These experiments have resulted in the isolation of a new toxic metabolite, which we call simatoxin. | |||||||||||
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