| ε-(γ-Glutamyl)lysine in Fibrin: Lack of Crosslink Formation in Factor XIII Deficiency | |||||||||||
Abstract | |||||||||||
| Fibrin clots formed in normal plasma contained about 6 mol of ε-(γ-glutamyl)lysine per mol of fibrin, whereas those formed in plasma from individuals with Factor XIII deficiency contained little or none of this crosslink (0.02-0.64 mol/mol of fibrin). Partial supplementation of the plasma with Factor XIII, at a single concentration tested, commensurately increased the number of crosslinks. | |||||||||||
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