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Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance

Abstract
Gene-expression analysis in cerebellum, heart and white adipose tissue from a knock-in mouse that harbors a human mutation and faithfully reproduces human resistance to thyroid hormone, uncovered complex multiple signaling pathways that mediate the molecular actions of TRβ mutants in vivo.

Publication details
Download http://www.pubmedcentral.gov/articlerender.fcgi?artid=416467
Publisher BioMed Central
Repository PubMed Central (PMC3 - NLM DTD) (United States)
Keywords Research
Type Text
Language Englisch