| Eph signalling functions downstream of Val to regulate cell sorting and boundary formation in the caudal hindbrain (2001) | |||||||||
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Abstract | |||||||||
| Development Printed Great Britain The Company Biologists Limited DEV Eph signalling functions downstream Val regulate cell sorting and boundary formation the caudal hindbrain Julie Cooke Cecilia Moens Lukas Roth Lindsey Durbin Kensuki Shiomi Caroline Brennan Charles Kimmel Steve Wilson and Nigel Holder Department Anatomy and Developmental Biology University College London Gower Street London Division Basic Sciences and Program Developmental Biology Fred Hutchinson Cancer Research Center Institute Present This Fairview Ave Seattle USA Neuroscience University Oregon Eugene USA address Division Basic Sciences Fred Hutchinson Cancer Research Center Fairview Ave Seattle USA paper dedicated the memory Nigel Holder Author for correspondence mail jcooke fhcrc org Accepted December published WWW January SUMMARY Rhombomeres are segmental units the developing vertebrate hindbrain that underlie the reiterated organisation cranial neural crest migration and neuronal differentiation valentino val zebrafish homologue the mouse bzip transcription factor encoding gene kreisler required for segment boundary formation caudal rhombomere val normally expressed and required for cells contribute this region val mutants region one rhombomere length and mixed identity lies between and While number genes involved establishing rhombomeric identity are known still largely unclear how segmental integrity established and boundaries are formed Members the Eph family receptor tyrosine kinases and their liga | |||||||||
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