| Non-protein amino acids in peptide design (2003) | |||||||||
Abstract | |||||||||
| An overview of the use of non-protein amino acids in the design of conformationally well-defined peptides, based on work from the author’s laboratory, is discussed. The crystal structures of several designed oligopeptides illustrate the use alpha-aminoisobutyric acid (Aib) in the construction of helices, D-amino acids in the design of helix termination segments and DPro–Xxx segments for nucleating of beta-hairpin structures. beta- and gamma-amino acid residues have been used to expand the range of designed polypeptide structures. | |||||||||
Publication details | |||||||||
| |||||||||
Publications citing this publication (1) | |||||||||
| |||||||||