| 2-(Acetamido)-4,5-dimethyl-N-(2-methyl-phenyl)thiophene-3-carboxamide (2004) | |||||||||
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| Acetamido dimethyl methylphenyl thiophene carboxamide Vasu Nirmala Deepak Chopra Mohand and Saravanane Vivekananda Degree College Bangalore Karnataka India bDepartment Physics Bangalore University Bangalore Karnataka India cSolid State and Structural Chemistry Unit Indian Institute Science Bangalore Karnataka India PES College Pharmacy Hanumanthanagar Bangalore Karnataka India and Ramaiah College Pharmacy Bangalore Karnataka India Correspondence mail deepak sscu iisc ernet The title compound O shows antibacterial and antifungal activities The dihedral angle between the thiophene and methylphenyl groups There are intraand intermolecular hydrogen bonds and intermolecular interactions Comment Schiff bases Csaszar Morvay Lakshmi Cohen and their derivatives thiophene ElMaghraby Dzhurayev Gewald possess antibacterial antitubercular and antifungal properties Sulfur containing Schiff bases are the most effective The title compound shows the above mentioned biological properties Mohan Saravanan Key indicators Single crystal ray study Mean R factor factor Data parameter ratio The molecular structure shown Fig and packing diagram shown Fig The C torsion angle indicating that the acetamide group and the thiophene ring are essentialy planar Table The dihedral angle between the least squares plane passing through the amide group and the methylphenyl group avoid steric interaction between the methyl and carbonyl groups intramolecular hydrogen bond Table forms pseudo six membered ring which | |||||||||
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