| Normal cognitive performance in patients with chronic alcoholism in contrast to patients with Korsakoff's syndrome (2000) | |||||||||
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| Normal Cognitive Performance Patients With Chronic Alcoholism Contrast Patients With Korsakoff Syndrome Lydia Krabbendam Pieter Jelle Visser Mayke Derix Frans Verhey D Paul Hofman Willem Verhoeven D Siegfried Tuinier D Jelle Jolles This study investigated which cognitive deficits are associated with chronic alcoholism Neuropsychological profiles and MRI brain structure volumes patients with Korsakoff syndrome patients with chronic alcoholism and healthy control subjects were compared The patients with alcoholism had normal cognitive performance and normal brain structure volumes The patients with Korsakoff syndrome had performance deficits tests memory visuoperceptual and executive functions well reduced brain structure volumes The results suggest that the cognitive deficits cannot ascribed mere chronic consumption alcohol cognitive deficits are present patients with chronic alcoholism this may point underlying brain disorder The Journal Neuropsychiatry and Clinical Neurosciences rolonged heavy alcohol consumption combination with severe thiamin deficiency may lead Korsakoff syndrome Fundamental this syndrome are profound anterograde and retrograde amnesia Impairments visuoperceptual and executive functions may also present but are less severe There some evidence that patients with chronic alcoholism also have deficits visuoperceptual and executive functions but few studies have directly compared the cognitive deficits the two groups patients Nonetheless this comparison impor | |||||||||
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