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Influence of body weight on response of Fischer 344 rats to anthrax lethal toxin.

Abstract
Groups of Fischer 344 rats were injected intravenously with Bacillus anthracis culture supernatant containing crude anthrax toxin. Times to death of rats given identical toxin preparations varied directly with the weights of the rats (P = 0.0001). In contrast to previous reports, the data indicate that rat weight must be taken into account during in vivo assays of anthrax lethal toxin activity.

Publication details
Download http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=203012
Repository PubMed Central (PMC3 - NLM DTD) (United States)
Keywords Research Article
Type Text
Language Englisch