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Sensitive Line Probe Assay That Simultaneously Detects Mutations Conveying Resistance to Lamivudine and Adefovir

Abstract
The INNO-LiPA HBV DR v2 assay is designed to detect hepatitis B virus mutations conveying resistance to lamivudine and adefovir. Our study confirms that this assay can simultaneously detect the presence of lamivudine and adefovir resistance mutations in clinical samples, has a high degree of concordance with sequencing, and can detect mutants earlier.

Publication details
Download http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1393162
Publisher American Society for Microbiology
Repository PubMed Central (PMC3 - NLM DTD) (United States)
Keywords Virology
Type Text
Language Englisch