Publication View

Development of a Fieldable, Rapid, Accurate and Sensitive Bio-Electronic, DNA Biosensor (2006)

Abstract
Integrated Nano-Technologies (INT) has developed novel electronic biosensor technology that will rapidly and accurately provide DNA-based field detection and identification of pathogenic organisms. The sensor is capable of detecting the binding of a single molecule of DNA or RNA and therefore does not require the use of PCR. The sensor chip can be engineered with an array of hundreds of independent test sites, which allows for confirmatory tests leading to a high level of specificity, the ability to screen for multiple threat agents simultaneously, and the capability to detect genetically engineered organisms. Biological agents continue to pose a major threat to U.S. troops as well as U.S. civilians both domestically and overseas. Rapid, accurate and sensitive detection and identification of biological agents is crucial to effective containment, neutralization and/or treatment. The U.S. military has an immediate need for a rapid, field deployable system for the detection and identification of biological agents, not only to protect military personnel from their effects, but also to contain and destroy them. An effective system must be: accurate, sensitive, rapid, easy to use, portable and field-ready. None of the currently available technologies meet all the necessary criteria.. See also ADM001736, Proceedings for the Army Science Conference (24th) Held on 29 November - 2 December 2004 in Orlando, Florida. The original document contains color images. See also ADM001849, presented at the Scientific Conference on Chemical and Biological Defense Research, held in Hunt Valley, MD, on 15-17 Nov 2004.

Publication details
Download http://handle.dtic.mil/100.2/ADA433463
Contributors INTEGRATED NANO-TECHNOLOGIES LLC ROCHESTER NY
Repository Defense Technical Information Center OAI-PMH Repository (United States)
Keywords BIOCHEMISRTY, CHEMICAL, BIOLOGICAL AND RADIOLOGICAL WARFARE, *BIOLOGICAL AGENTS, *DEOXYRIBONUCLEIC ACIDS, *BIOLOGICAL DETECTION, MILITARY PERSONNEL, DEPLOYMENT, THREATS, PATHOGENIC MICROORGANISMS, HIGH RELIABILITY, BIOELECTRICITY, OVERSEAS, FIELD CONDITIONS, TEST FACILITIES, SENSITIVITY, NEUTRALIZATION, DETECTORS, SYMPOSIA, *DNA BIOSENSORS, COMPONENT REPORTS, PCR(POLYMERASE CHAIN REACTION)
Language eng