| Lateral diffusion in substrate-supported lipid monolayers as a function of ambient relative humidity (2002) | |||||||||||
Abstract | |||||||||||
| Lateral Diffusion Substrate Supported Lipid Monolayers Function Ambient Relative Humidity Tobias Baumgart and Andreas Offenha usser Max Planck Institute for Polymer Research Mainz Germany ABSTRACT analyzed the influence water activity the lateral self diffusion supported phospholipid monolayers Lipid monolayer membranes were supported polysaccharide cushions chitosan and agarose glass simple diffusion model was derived based activated diffusion with activation energy which depends the hydration state the lipid headgroup crucial assumption the derived model that can calculated assuming exponential decay the humidity dependent disjoining pressure the monolayer substrate interface with respect the equilibrium separation distance plot against where the measured diffusion coefficient and and are the partial water pressures saturation and particular relative humidity respectively was observed linear all cases for differing lipids lateral monolayer pressures temperatures and substrates accordance with the above mentioned diffusion model indications for humidity induced first order phase transitions the supported phospholipid monolayers were found Many biological processes such vesicle fusion and recognition processes involve dehydration hydration cycles and can expected that the water activity significantly affects the kinetics these processes manner similar that examined the present work INTRODUCTION Lipid membranes supported planar substrate receive considerable interest both from | |||||||||||
Publication details | |||||||||||
| |||||||||||
Cited publications (4) | |||||||||||