Publication View

Efficacy and tolerability of racecadotril in the treatment of cholera in adults: a double blind, randomised, controlled clinical trial

Abstract
Background: The enkephalins, endogenous opiate substances, act as neurotransmitters along the entire digestive tract where they elicit intestinal antisecretory activity without affecting intestinal transit time or motility. Racecadotril, through inhibition of enkephalinase, reinforces the physiological activity of endogenous enkephalins and, therefore, shows intestinal antisecretory activity.

Publication details
Download http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1773819
Publisher Copyright 2003 by Gut
Repository PubMed Central (PMC3 - NLM DTD) (United States)
Keywords Small Intestine
Type Text
Language Englisch