| Binomial Distribution Sample Confidence Interval Estimation for Positive and Negative Likelihood Ratio Medical Key Parameters | |||||||||||||
Abstract | |||||||||||||
| Likelihood Ratio medical key parameters calculated on categorical results from diagnostic tests are usually express accompanied with their confidence intervals, computed using the normal distribution approximation of binomial distribution. The approximation creates known anomalies, especially for limit cases. In order to improve the quality of estimation, four new methods (called here RPAC, RPAC0, RPAC1, and RPAC2) were developed and compared with the classical method (called here RPWald), using an exact probability calculation algorithm. | |||||||||||||
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