| No maternally inherited diabetes and deafness mutations in a sample of 193 Tasmanian diabetics with glaucoma (2007) | |||||||||
Abstract | |||||||||
| We tested the hypothesis that the presence of the mitochondrial 3243 A-G mutation responsible for maternally inherited diabetes and deafness (MIDD)1 may partly explain the association between glaucoma and diabetes mellitus. The 3243 AG mutation has been estimated to be responsible for 1–3% of the non-insulin-dependent diabetes mellitus cases in Northern Europe2 and approximately 1% in Japan.3 We tested 193 DNA samples collected from Tasmanians with both diseases recruited through the Glaucoma Inheritance Study in Tasmania.4 No cases with the 3243 A-G mutation were detected. | |||||||||
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