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Th-17, Monokines, Collagen Type V, and Primary Graft Dysfunction in Lung Transplantation

Bobadilla, Joseph L.,
Love, Robert B.,
Jankowska-Gan, Ewa,
Xu, Qingyong,
Haynes, Lynn D.,
Braun, Ruedi K.,
Hayney, Mary S.,
Munoz Del Rio, Alejandro,
Meyer, Keith,
Greenspan, Daniel S.,
Torrealba, Jose,
Heidler, Kathleen M.,
Cummings, Oscar W.,
Iwata, Takekazu,
Brand, David,
Presson, Robert,
Burlingham, William J.,
Wilkes, David S.

Abstract

Rationale: The pathogenesis of primary graft dysfunction (PGD), a serious complication of lung transplantation, is poorly understood. Human studies and rodent models have shown that collagen type V (col[V]), stimulates IL-17–dependent cellular immunity after lung transplantation.

Publication details

Download	http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2267340
Publisher	American Thoracic Society
Repository	PubMed Central (PMC3 - NLM DTD) (United States)
Keywords	H. Transplantation
Type	Text
Language	English