| Case(Control)-Free Multi-SNP Combinations in Case-Control Studies (2008) | |||||||||||||
Abstract | |||||||||||||
| Several genome-wide searches for disease-associated gene variations have been recently reported (Spinola et al, 2006; Herbert et al, 2006). However, complex diseases can be caused by combinations of several unlinked gene variations. Unfortunately, an exhaustive search among all possible corresponding multi-SNPs can be unfeasible even for small number of SNPs let alone the | |||||||||||||
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