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Role of the Campylobacter jejuni Cj1461 DNA Methyltransferase in Regulating Virulence Characteristics▿ †

Abstract
Mutation of the cj1461 predicted methyltransferase gene reduced the motility of Campylobacter jejuni 81-176. Electron microscopy revealed that the mutant strain had flagella but with aberrant structure. The Δcj1461 mutant was sevenfold more adherent to but 50-fold less invasive of INT-407 human epithelial cells than the wild type.

Publication details
Download http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2565991
Publisher American Society for Microbiology (ASM)
Repository PubMed Central (PMC3 - NLM DTD) (United States)
Keywords Enzymes and Proteins
Type Text
Language English