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How adsorption influences DNA denaturation (2009)

Abstract
The thermally induced denaturation of DNA in the presence of attractive solid surface is studied. The two strands of DNA are modeled via two coupled flexible chains without volume interactions. If the two strands are adsorbed on the surface, the denaturation phase-transition disappears. Instead, there is a smooth crossover to a weakly naturated state. Our second conclusion is that even when the inter-strand attraction alone is too weak for creating a naturated state at the given temperature, and also the surface-strand attraction alone is too weak for creating an adsorbed state, the combined effect of the two attractions can lead to a naturated and adsorbed state.. Comment: 21 pages, 1 figure

Publication details
Download http://arxiv.org/abs/0905.3328
Repository arXiv (United States)
Keywords Condensed Matter - Soft Condensed Matter, Condensed Matter - Mesoscale and Nanoscale Physics, Quantitative Biology - Biomolecules
Type text