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Peripheral arterial disease in polymyalgia rheumatica (2009)

Abstract
Abstract Patients with polymyalgia rheumatica have been shown to have an increased risk of peripheral arterial disease on longitudinal follow-up. Possible explanations for this include premature atherosclerosis related to chronic inflammation, as with other inflammatory rheumatological conditions. Alternatively, polymyalgia rheumatica can be associated with vasculitis, even in the absence of clinical giant cell arteritis, and peripheral vascular disease may represent subclinical vasculitis. Further work is required to elucidate the reasons for this increased risk. Currently, it would remain reasonable to aggressively control modifiable atherosclerotic risk factors.

Publication details
Download http://arthritis-research.com/content/11/3/111
Publisher BioMed Central Ltd.
Repository BioMed Central (United Kingdom)
Type Editorial
Language English