| Premorbid IQ as a predictor for the course of IQ in first onset patients with schizophrenia: A 10-year follow-up study (2006) | |||||||||||||
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| The aim of the present study was to examine the longitudinal course of IQ and its heterogeneity in patients with schizophrenia, from the perspective of the two main "subtypes" of schizophrenia described in the literature: progressive cognitive deficit versus cognitive stabilisation or recovery. Premorbid IQ scores and WAIS IQ scores of 100 first onset patients were obtained at first hospitalization (T1) and after 10 years (T2). Significant changes in IQ over time were found, representing (i) at T1, a deterioration compared to premorbid intelligence (B=-6.3, 95% CI -9.5 to -3.0, p. University Psychiatric Center Katholieke Universiteit Leuven, Leuvensesteenweg 517, 3070 Kortenberg, Belgium; Department of Psychiatry and Neuropsychology, EURON, South Limburg Mental Health Research and Teaching Network, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands. | |||||||||||||
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