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Diels-alder reactions of 6-alkyl-3,5-dichloro-2h-1,4-oxazin-2-ones with alkynes - synthesis of 3,5-disubstituted 2,6-dichloropyridines (1991)

Abstract
The Diels-Alder reaction of 6-alkyl-3,5-dichloro-2H-1,4-oxazin-2-ones 1 with different types of acetylenic compounds 2 is shown to be a versatile method for the generation of variously substituted 2,6-dichloropyridines. In most cases a high degree of regioselectivity and a high yield of 3,5-disubstituted 2,6-dichloropyridines 3 is obtained.

Publication details
Publisher Georg thieme verlag
Repository Lirias is a research document repository at KULeuven (Belgium)
Keywords halogenated pyridines, cyanohydrins
Type Description (Metadata) only, IT, article
Language English
Relation Synthesis-stuttgart issue:9 pages:765-768