| EFFECT OF ETHANOL CHALLENGE ON SERUM GLYCOPROTEINS IN ALCOHOLIC AND NON-ALCOHOLIC LIVER DISEASE (1987) | |||||||||||||
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| The effects of acute ethanol challenge on serum glycoprotein concentrations in man were studied. Serum levels of haptoglobin, α-2-macroglobulin and pre-albumin were measured fasting and 6 hr after oral ethanol 0.75g/kg body weight in 8 healthy controls, 13 patients with alcoholic liver disease and 13 with non-alcoholic-related liver damage, both patient groups being further subdivided into those with and without cirrhosis. Basal levels of haptoglobin were significantly higher in non-cirrhotic alcoholics than controls and pre-albumin levels were lower in non-alcohol-related cirrhotic liver disease. In response to ethanol challenge, no consistent change was observed in any group, nor was there any significant difference between groups. There was, however, a significant correlation (r=0.53, P | |||||||||||||
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