| Can the left ventricular early diastolic tissue-to-blood time interval be used to identify a normal pulmonary capillary wedge pressure? (2007) | |||||||||||||
Abstract | |||||||||||||
| The pulsed Doppler early diastolic left ventricular (LV) tissue (e)–blood (E) onset temporal relationship (e–E) is suggested to predict pulmonary capillary wedge pressure (PCWP), through the formulas: tau=32+0.7(e–E) and PCWP=LV end-systolic pressurexe–IVRT/tau. Small changes/errors in E could influence the quotient IVRT/tau by oppositely affecting IVRT and e–E. At rest in 50 healthy individuals we noted: e–E: 2±14ms; IVRT: 89±17ms; calculated tau: 33±10ms; and PCWP: 9±9mmHg (>12mmHg in 28%). Non-pharmacological preload alterations in 14 individuals rendered an intraindividual PCWP-fluctuation of up to 40mmHg. This application may therefore not be clinically robust. | |||||||||||||
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