| The Association of Autoimmune Disorders with Inflammatory Bowel Disease (1989) | |||||||||||||
Abstract | |||||||||||||
| Medical records of patients with ulcerative colitis (n= 858), Crohn's disease (n= 378) and coeliac disease (n = 148) were examined to determine the prevalence of associated autoimmune disorders. Of outpatient controls (n= 300), 2 per cent had at least one autoimmune disorder, compared to 7 per cent with ulcerative colitis, 2 per cent with Crohn's disease and 6 per cent with coeliac disease. Inclusion of primary sclerosing cholangitis with the autoimmune disorders increased the overall prevalence in ulcerative colitis to over 9 per cent The results provide further indirect evidence of involvement of autoimmune mechanisms in the pathogenesis of ulcerative colitis. | |||||||||||||
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