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Maximum Motif Problem in Vertex-Colored Graphs (2009)

Abstract
Searching for motifs in graphs has become a crucial problem in the analysis of biological networks. In this context, dierent graph motif problems have been considered [12, 6, 4]. Pursuing a line of research pioneered by Lacroix et al. [12], we introduce in this paper a new graph motif problem: given a vertex colored graph G and a motif M, where a motif is a multiset of colors, nd a maximum cardinality submotif M' included in M that occurs as a connected motif in G. We prove that the problem is APX-hard even in the case where the target graph is a tree of maximum degree 3, the motif is actually a set and each color occurs at most twice in the tree. We complement these results by presenting two fixed-parameter algorithms for the problem, where the parameter is the size of the solution. Finally, we give exact efficient exponential-time algorithms for the problem.

Publication details
Download HAL:http://hal.archives-ouvertes.fr/hal-00416463/en/, http://hal.archives-ouvertes.fr/docs/00/41/64/63/PDF/CPM2009_Paper.pdf
Publisher HAL - CCSD
Repository INRIA a CCSD electronic archive server based on P.A.O.L (France)
Keywords [INFO:INFO_DS] Computer Science/Data Structures and Algorithms, [INFO:INFO_CC] Computer Science/Computational Complexity, [INFO:INFO_BI] Computer Science/Bioinformatics, [SDV:BIBS] Life Sciences/Quantitative Methods
Type text
Language English
Coverage Lille