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Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease (2007)

Abstract
Objective: Parkinson's disease (PD) is a neurodegenerative condition that typically presents as a movement disorder but is known to be associated with variable degrees of cognitive impairment including dementia. We investigated the genetic basis of susceptibility to and cognitive heterogeneity of this disease.. This work was supported by the Medical Research Council (RG38582, R.A.B.), the Parkinson’s Disease Society (RG39906, R.A.B.), a Postdoctoral Fellowship of the Research Foundation–Flanders (FWO–Vlaanderen; A.G.), a Patrick Berthoud Clinical Research Fellowship (C.H.W.-G.), and a Raymond and Beverley Sackler studentship (C.H.W.-G.).

Publication details
Publisher Wiley-liss
Repository Lirias is a research document repository at KULeuven (Belgium)
Keywords progressive supranuclear palsy, whole-genome association, linkage disequilibrium, gene polymorphism, no evidence, haplotype, expression, transcription, population, inversion
Type Article, IT, article
Language English
Relation Annals of neurology vol:62 issue:2 pages:145-153