| Recollection-based memory in frontotemporal dementia: Implications for theories of long-term memory (2002) | |||||||||||
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Abstract | |||||||||||
| Brain Recollection based memory frontotemporal dementia implications for theories long term memory Jon Simons Mieke Verfaellie Clare Galton Bruce Miller John Hodges and Kim Graham Cognition and Brain Sciences Unit and University Neurology Unit Addenbrooke Hospital Cambridge Memory Disorders Research Center Boston University School Medicine Boston and Mount Zion Hospital University California San Francisco USA MRC Correspondence Jon Simons Institute Cognitive Neuroscience University College London Alexandra House Queen Square London Kim Graham MRC Cognition and Brain Sciences Unit Chaucer Road Cambridge mail jon simons ucl kim graham mrc cbu cam Summary has been convincingly demonstrated that patients with semantic dementia the temporal variant frontotemporal dementia can show intact recognition memory for pictorial stimuli yet the contribution made recollective processes this ability and the status associated neural regions have not been investigated the disease Here used both source monitoring paradigm and associative memory test evaluate the ability patients with semantic dementia use recollection based memory processes and volumetric MRI technique assess the extent atrophy the hippocampus Although some patients showed impaired source and associative memory many performed well control participants Importantly status semantic knowledge measured tests compre hension and production did not predict recollectionbased memory ability There was signi cant positive correlation betwe | |||||||||||
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