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Percutaneous pulmonary valve implantation in humans: results in 59 consecutive patients (2005)

Khambadkone,
S.,
Coats,
L.,
Taylor,
A.M.,
Boudjemline,
Y.,
Derrick,
G.,
Tsang,
V.,
Cooper,
J.,
Muthurangu,
V.,
Hegde,
S.R.,
Razavi,
R.S.,
Pellerin,
D.,
Deanfield,
J.E.,
Bonhoeffer,
P.

Abstract

BACKGROUND: Right ventricular outflow tract (RVOT) reconstruction with valved conduits in infancy and childhood leads to reintervention for pulmonary regurgitation and stenosis in later life. METHODS AND RESULTS: Patients with pulmonary regurgitation with or without stenosis after repair of congenital heart disease had percutaneous pulmonary valve implantation (PPVI). Mortality, hemodynamic improvement, freedom from explantation, and subjective and objective changes in exercise tolerance were end points. PPVI was performed successfully in 58 patients, 32 male, with a median age of 16 years and median weight of 56 kg. The majority had a variant of tetralogy of Fallot (n=36), or transposition of the great arteries, ventricular septal defect with pulmonary stenosis (n=8). The right ventricular (RV) pressure (64.4+/-17.2 to 50.4+/-14 mm Hg, P

Publication details

Repository	UCL Research Publications Index (MyOPIA) (United Kingdom)
Keywords	16, 2, A, AGE, AND, ARTERIES, ARTERY, ARTICLE, CAPACITY, CHILDHOOD, CONDUITS, congenital, Congenital Heart Disease, DEFECT, DISEASE, EXERCISE, Exercise Tolerance, FALLOT, FOR, gradient, GREAT-ARTERIES, HAD, HEART, heart disease, HEART-DISEASE, Human, HUMANS, IM, IMPLANTATION, INCREASE, INFANCY, IS, JOURNAL, LA, LIFE, LONDON, Low, Male, metabolic, METHODS, MM, MORTALITY, MRI, NO, OF, PATIENT, patients, percutaneous, PR, Pressure, PULMONARY, Pulmonary Valve, reconstruction, REPAIR, Result, RISK, SIGNIFICANT INCREASE, STENOSIS, stroke, TETRALOGY, Tetralogy of Fallot, THE, TRACT, TRANSPOSITION, UK, VARIANT, VOLUME, WEIGHT
Type	JOUR
Relation	1189-1197