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Monte Carlo simulations of flexible molecules in a static electric field: electric dipole and conformation (2005)

Abstract
We have performed Monte Carlo replica-exchange method calculations on the gas phase tryptophan-glycine dipeptide in a static electric field. At low electric field, the average dipole of the molecule follows the Langevin–Debye equation. At high electric field, a deviation from this law is observed and the analysis of the results shows that the external field modifies the conformation of the molecules. This opens the way to a possible control of the conformation of gas phase biomolecules with static electric fields.

Publication details
Download http://hal.ccsd.cnrs.fr/ccsd-00018545/en/
Publisher HAL - CCSd - CNRS
Contributors Pierre Poulain
Repository CCSd/HAL : e-articles server (based on gBUS) (France)
Keywords Physics/Physics/Biological Physics, Physics/Condensed Matter/Statistical Mechanics
Type ARTJOURNAL
Language Englisch
Coverage peptide ; Monte Carlo ; parallel tempering ; Monte Carlo d'échange ; AMBER ; dipôle électrique ; susceptibilité électrique