| Microarray-based resequencing of multiple Bacillus anthracisisolates (2004) | |||||||||||
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| Abstract We used custom-designed resequencing arrays to generate 3.1 Mb of genomic sequence from a panel of 56 Bacillus anthracis strains. Sequence quality was shown to be very high by replication (discrepancy rate of 7.4 × 10 -7 ) and by comparison to independently generated shotgun sequence (discrepancy rate < 2.5 × 10 -6 ). Population genomics studies of microbial pathogens using rapid resequencing technologies such as resequencing arrays are critical for recognizing newly emerging or genetically engineered strains. | |||||||||||
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