Streicher, S L, Deleo, A B, Magasanik, B
We studied the physiology of cells of Klebsiella aerogenes containing the structural gene for glutamine synthetase (glnA) of Escherichia coli on an episome. The E. coli glutamine synthetase...
3-Deoxy-D-arabino-heptulosonic acid 7-phosphate synthase mutants of Salmonella typhimurium.
The first committed step of aromatic amino acid biosynthesis in Salmonella typhimurium was shown to be catalyzed by three isoenzymes of 3-deoxy-D-arabino-heptulosonic acid 7-phosphate (DAHP)...
Identification of the structural gene for glutamine synthetase in Klebsiella aerogenes.
Mutations at two sites of the Klebsiella aerogenes chromosome, unlinked by transduction with phages PW52 and P1, result in the lack of enzymatically active glutamine synthetase. A mutation in the...
p53 transformation-related protein: detection of an associated phosphotransferase activity.
Jay, G, Khoury, G, DeLeo, A B, Dippold, W G, Old, L J
Malignant cells of the mouse transformed by a variety of different agents have been found to express high levels of a 53,000 Mr phosphoprotein (designated p53). Little or no p53 can be detected in...
Tumor rejection antigens of chemically induced sarcomas of inbred mice.
Srivastava, P K, DeLeo, A B, Old, L J
Chemically induced sarcomas of inbred mice are immunogenic in syngeneic hosts, and preimmunization with tumor cells leads to resistance to subsequent tumor transplants. The tumor rejection antigens...
Mercer, W E, Nelson, D, DeLeo, A B, Old, L J, Baserga, R
Monoclonal antibody directed against the transformation-related protein p53 was microinjected manually into the nuclei of quiescent Swiss 3T3 mouse cells. The cells were subsequently stimulated with...
Hopkins, N, Besmer, P, DeLeo, A B, Law, L W
We transformed BALB/3T3 mouse cells with cellular DNA extracted from the Meth A sarcoma, a 3-methylcholanthrene-induced tumor of BALB/c mice, and asked whether foci arising in the transfection...
DeLeo, A B, Jay, G, Appella, E, Dubois, G C, Law, L W, Old, L J
Antisera prepared against BALB/c Meth A sarcoma in syngeneic or compatible F1 mice recognize a protein with an apparent molecular weight of 53,000 in extracts of [35S]methionine-labeled transformed...
Protein p53 and inducer-mediated erythroleukemia cell commitment to terminal cell division.
Shen, D W, Real, F X, DeLeo, A B, Old, L J, Marks, P A, Rifkind, R A
Inducer-mediated murine erythroleukemia cell (MELC) differentiation provides a model for examining factors determining terminal cell differentiation. The nuclear protein, p53, has been implicated as...
Streicher, S L, Deleo, A B, Magasanik, B
We studied the physiology of cells of Klebsiella aerogenes containing the structural gene for glutamine synthetase (glnA) of Escherichia coli on an episome. The E. coli glutamine synthetase...
3-Deoxy-D-arabino-heptulosonic acid 7-phosphate synthase mutants of Salmonella typhimurium.
The first committed step of aromatic amino acid biosynthesis in Salmonella typhimurium was shown to be catalyzed by three isoenzymes of 3-deoxy-D-arabino-heptulosonic acid 7-phosphate (DAHP)...
Identification of the structural gene for glutamine synthetase in Klebsiella aerogenes.
Mutations at two sites of the Klebsiella aerogenes chromosome, unlinked by transduction with phages PW52 and P1, result in the lack of enzymatically active glutamine synthetase. A mutation in the...
p53 transformation-related protein: detection of an associated phosphotransferase activity.
Jay, G, Khoury, G, DeLeo, A B, Dippold, W G, Old, L J
Malignant cells of the mouse transformed by a variety of different agents have been found to express high levels of a 53,000 Mr phosphoprotein (designated p53). Little or no p53 can be detected in...
Tumor rejection antigens of chemically induced sarcomas of inbred mice.
Srivastava, P K, DeLeo, A B, Old, L J
Chemically induced sarcomas of inbred mice are immunogenic in syngeneic hosts, and preimmunization with tumor cells leads to resistance to subsequent tumor transplants. The tumor rejection antigens...
Mercer, W E, Nelson, D, DeLeo, A B, Old, L J, Baserga, R
Monoclonal antibody directed against the transformation-related protein p53 was microinjected manually into the nuclei of quiescent Swiss 3T3 mouse cells. The cells were subsequently stimulated with...
Hopkins, N, Besmer, P, DeLeo, A B, Law, L W
We transformed BALB/3T3 mouse cells with cellular DNA extracted from the Meth A sarcoma, a 3-methylcholanthrene-induced tumor of BALB/c mice, and asked whether foci arising in the transfection...
DeLeo, A B, Jay, G, Appella, E, Dubois, G C, Law, L W, Old, L J
Antisera prepared against BALB/c Meth A sarcoma in syngeneic or compatible F1 mice recognize a protein with an apparent molecular weight of 53,000 in extracts of [35S]methionine-labeled transformed...
Protein p53 and inducer-mediated erythroleukemia cell commitment to terminal cell division.
Shen, D W, Real, F X, DeLeo, A B, Old, L J, Marks, P A, Rifkind, R A
Inducer-mediated murine erythroleukemia cell (MELC) differentiation provides a model for examining factors determining terminal cell differentiation. The nuclear protein, p53, has been implicated as...