What is the risk of mortality following diagnosis of multidrug-resistant HIV-1? (2008)
Grover, D., Copas, A., Green, H., Edwards, S. G., Dunn, D. T., Sabin, C., ...
Objectives To estimate the risk of death and examine the predictors of death and virological/immunological response, following diagnosis of multidrug-resistant (MDR) HIV-1 in a UK multicentre cohort...
Miller, R.F., Allen, E., Copas, A., Singer, M., Edwards, S.G.
Background: Despite a decline in incidence of Pneumocystis jirovecii pneumonia (PCP), severe PCP continues to be a common cause of admission to the intensive care unit (ICU) where mortality remains...
Incentives for voluntary HIV testing in NHS staff (2006)
Hamill, M., Copas, A., Murphy, S. M.
Background HIV seroprevalence is rising in the United Kingdom. While acceptability of HIV testing has been explored among many groups there is a paucity of data regarding voluntary HIV counselling...
Incentives for voluntary HIV testing in NHS staff (2006)
Hamill, M., Copas, A., Murphy, S. M.
Background HIV seroprevalence is rising in the United Kingdom. While acceptability of HIV testing has been explored among many groups there is a paucity of data regarding voluntary HIV counselling...
Genotypic variation in Pneumocystis jirovecii isolates in Britain (2005)
Miller, R.F., Lindley, A.R., Copas, A., Ambrose, H.E., Davies, R.J.O., Wakefield, A.E.
Background: Pneumocystis jirovecii is the cause of Pneumocystis pneumonia (PCP) in immunosuppressed humans. Asymptomatic colonisation with P jirovecii may occur in patients with minor...
McCadden, A., Fenton, K.A., McManus, S., Mercer, C.H., Erens, B., Carder, C., ...
Background: Noninvasive molecular tests for bacterial sexually transmitted infections (STIs) provide new opportunities for testing in nonclinical settings. Little information is available on the...
Lascar, R.M., Lopes, A.R., Gilson, R.J., Dunn, C., Johnstone, R., Copas, A., ...
Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)–positive patients and an increasing cause of morbidity and mortality. The CD8+ T cell response...
Lascar, R.M., Lopes, A.R., Gilson, R.J., Dunn, C., Johnstone, R., Copas, A., ...
Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)-positive patients and an increasing cause of morbidity and mortality. The CD8(+) T cell response...
Ward, H., Mercer, C.H., Wellings, K., Fenton, K., Erens, B., Copas, A., ...
Background: In the United Kingdom the incidence of sexually transmitted infections (STI) and risky sexual behaviours is increasing. The role of commercial sex in this trend is poorly understood....
Pupil-led sex education in England (RIPPLE study): cluster-randomised intervention trial (2004)
Stephenson, J.M., Strange, V., Forrest, S., Oakley, A., Copas, A., Allen, E., ...
Background: Improvement of sex education in schools is a key part of the UK government's strategy to reduce teenage pregnancy in England. We examined the effectiveness of one form of peer-led sex...
Pupil-led sex education in England (RIPPLE study) : cluster-randomised intervention trial. (2004)
Stephenson, J., Strange, V., Forrest, S., Oakley, A., Copas, A., Allen, E., ...
Background Improvement of sex education in schools is a key part of the UK government's strategy to reduce teenage pregnancy in England. We examined the effectiveness of one form of peer-led sex...
Bourboulia, D., Aldam, D., Lagos, D., Allen, E., Williams, I., Cornforth, D., ...
Objective: To investigate the effect of highly active antiretroviral therapy (HAART) on Kaposi sarcoma-associated herpesvirus (KSHV) DNA load, anti-KSHV antibody responses and KSHV-specific CD8 T...
Bonell, C. P., Strange, V. J., Stephenson, J. M., Oakley, A. R., Copas, A., Forrest, S. P., ...
Study objective: The UK government argues that social exclusion increases risk of teenage pregnancy and that educational factors may be dimensions of such exclusion. The evidence cited by the...
A school-based randomized controlled trial of peer-led sex education in England. (2003)
Stephenson, J. M., Oakley, A., Johnson, A. M., Forrest, S., Strange, V., Charleston, S., ...
This article discusses the design of an ongoing cluster-randomized trial comparing two forms of school-based sex education in terms of educational process and sexual health outcomes. Twenty-nine...
National Survey of Sexual Attitudes and Lifestyles II: reference tables and summary report. (2003)
Erens, B., McManus, S., Prescott, P., Field, J., Johnson, A., Wellings, K., ...
Sadiq, S.T., Taylor, S., Kaye, S., Bennett, J., Johnstone, R., Byrne, P., ...
Background: High seminal plasma HIV-1 RNA loads (SVL) have been reported during gonococcal, non-gonococcal and chlamydial urethritis in patients not taking antiretroviral therapy. Objective: To...
Condoms and seat belts: the parallels and the lessons (2000)
Richens, J., Imrie, J., Copas, A.
Condoms and car seat belts are applied to the human body to save lives. For both, there is an abundance of evidence of benefit to individuals directly exposed to risk. When evidence of benefit is...
Grun, L., Tassano-Smith, J., Carder, C., Johnson, A. M., Robinson, A., Murray, E., ...
OBJECTIVES: To estimate the prevalence of Chlamydia trachomatis in asymptomatic women attending general practice: to assess the potential of the ligase chain reaction as a screening tool; and to...
A case control study of HIV seroconversion in gay men, 1988-1993: what are the current risk factors?
Williams, D I, Stephenson, J M, Hart, G J, Copas, A, Johnson, A M, Williams, I G
OBJECTIVE: To investigate current risk factors for HIV seroconversion among homo/bisexual men. DESIGN: Matched case control study in a large STD clinic in central London. Data on risk factors were...
HIV partner notification policy and practice within GUM clinics in England: where are we now?
Fenton, K A, Copas, A, Johnson, A M, French, R, Petruckevitch, A, Adler, M W
OBJECTIVES: To evaluate the extent to which larger genitourinary medicine (GUM) clinics in England have established local clinic policies for HIV Partner Notification (PN) and to describe the process...
Fenton, K., Copas, A., Mitchell, K., Elam, G., Carder, C., Ridgway, G., ...
websiteextra
Fenton, K, Chinouya, M, Davidson, O, Copas, A
Objectives: To describe the demographic and behavioural factors associated with HIV testing among migrant Africans in London.
Herpes simplex virus type 1 infection: a sexually transmitted infection of adolescence?
Cowan, F, Copas, A, Johnson, A, Ashley, R, Corey, L, Mindel, A
Design: Cross sectional study with HSV-1 antibody testing performed by University of Washington western blot assay.
Stephenson, J, Imrie, J, Davis, M, Mercer, C, Black, S, Copas, A, ...
Background/objective: There is concern that use of highly active antiretroviral therapy (HAART) may be linked to increased sexual risk behaviour among homosexual men. We investigated sexual risk...
Smith, R, Copas, A, Prince, M, George, B, Walker, A, Sadiq, S
Objectives: To determine the reliability of the diagnosis of non-gonococcal urethritis (NGU), and the variation between and within microscopists, from urethral smears at a large London genitourinary...
Haddow, L, Bunn, A, Copas, A, Gilson, R, Prince, M, Ridgway, G, ...
Background/objectives: The criteria for the diagnosis of non-gonococcal urethritis (NGU) on a Gram stained urethral smear are derived from previous studies which used culture as a diagnostic test for...
An evidence based approach to testing for antibody to herpes simplex virus type 2
Copas, A, Cowan, F, Cunningham, A, Mindel, A
Objectives: To establish whether a simple risk scoring system, based on limited information, can reflect the variation in HSV-2 prevalence in a population, and whether a common system can be used...
Home screening for chlamydial genital infection: is it acceptable to young men and women?
Stephenson, J., Carder, C., Copas, A., Robinson, A., Ridgway, G., Haines, A.
Objectives: To determine the acceptability, to young men and women, of home screening for chlamydial infection.
Copas, A, Wellings, K, Erens, B, Mercer, C, McManus, S, Fenton, K, ...
Objectives: The 1990–1 British national probability sample survey of sexual attitudes and lifestyles (Natsal 1990) was repeated in 1999–2001 (Natsal 2000) to update population estimates of risk...
Sadiq, S, Taylor, S, Copas, A, Bennett, J, Kaye, S, Drake, S, ...
Objectives: To examine the effects of urethritis and its treatment on semen plasma HIV-1 RNA load in HIV-1 infected men not receiving antiretroviral therapy (ART), in a developed world setting.
Bonell, C, Strange, V, Stephenson, J, Oakley, A, Copas, A, Forrest, S, ...
Study objective: The UK government argues that “social exclusion” increases risk of teenage pregnancy and that educational factors may be dimensions of such exclusion. The evidence cited by the...
Bonell, C, Allen, E, Strange, V, Copas, A, Oakley, A, Stephenson, J, ...
Study objective: To examine whether attitude to school is associated with subsequent risk of teenage pregnancy. To test two hypotheses that attitude to school is linked to pregnancy via pathways...
Genotypic variation in Pneumocystis jirovecii isolates in Britain
Miller, R, Lindley, A, Copas, A, Ambrose, H, Davies, R, Wakefield, A
Background: Pneumocystis jirovecii is the cause of Pneumocystis pneumonia (PCP) in immunosuppressed humans. Asymptomatic colonisation with P jirovecii may occur in patients with minor...
Changes in the circumstances of young mothers in Britain: 1990 to 2000
Nanchahal, K., Wellings, K., Barrett, G., Copas, A., Mercer, C., Macmanus, S., ...
Objectives: To assess changes between 1990 and 2000 in the circumstances of women who became mothers before the age of 18.
Mercer, C, Fenton, K, Johnson, A, Copas, A, Macdowall, W, Erens, B, ...
Objective: To identify sociodemographic, sexual, and health behavioural and attitudinal factors associated with reporting sexual function problems.
The effects of early syphilis on CD4 counts and HIV-1 RNA viral loads in blood and semen
Sadiq, S, McSorley, J, Copas, A, Bennett, J, Edwards, S, Kaye, S, ...
Objective: To examine the effect of early syphilis on blood and semen plasma HIV-1 viral loads and CD4 counts.
Factors associated with HIV testing among black Africans in Britain
Burns, F, Fenton, K, Morison, L, Mercer, C, Erens, B, Field, J, ...
Design: We analysed data from the second British National Survey of Sexual Attitudes and Lifestyles (Natsal 2000)—a stratified national probability sample survey conducted between 1999–2001. Data...
Ward, H, Mercer, C, Wellings, K, Fenton, K, Erens, B, Copas, A, ...
Background: In the United Kingdom the incidence of sexually transmitted infections (STI) and risky sexual behaviours is increasing. The role of commercial sex in this trend is poorly understood....