A. D. Blackwell

Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion (2006)

Roiser, J.P., Blackwell, A.D., Cools, R., Clark, L., Rubinsztein, D.C., Robbins, T.W., ...

The serotonin (5-HT) system is implicated in incentive motivational processes. The present study utilized the acute tryptophan depletion (ATD) procedure to investigate the effect of temporarily...

The subjective and cognitive effects of acute phenylalanine and tyrosine depletion in patients recovered from depression (2005)

Roiser, J.P., McLean, A., Ogilvie, A.D., Blackwell, A.D., Bamber, D.J., Goodyer, I., ...

Although there is evidence for the involvement of dopamine (DA) in unipolar depression, no published study has yet used the technique of acute phenylalanine and tyrosine depletion (APTD), a dietary...

Reinforcement and Reversal Learning in First-Episode Psychosis

Murray, G. K., Cheng, F., Clark, L., Barnett, J. H., Blackwell, A. D., Fletcher, P. C., ...

Background: Abnormalities in reinforcement learning and reversal learning have been reported in psychosis, possibly secondary to subcortical dopamine abnormalities. Methods: We studied simple...