Secondary amenorrhoea after total body irradiation in pre-puberty.
Albanese, A, Leiper, A D, Pritchard, J, Stanhope, R
Bone marrow transplant (BMT) has been used as part of the overall treatment of refractory malignant diseases. High dose cyclophosphamide and total body irradiation (TBI) are frequently used as...
Secondary amenorrhoea after total body irradiation in pre-puberty.
Albanese, A, Leiper, A D, Pritchard, J, Stanhope, R
Bone marrow transplant (BMT) has been used as part of the overall treatment of refractory malignant diseases. High dose cyclophosphamide and total body irradiation (TBI) are frequently used as...
Neuropsychological and neurological outcome after relapse of lymphoblastic leukaemia.
Christie, D, Battin, M, Leiper, A D, Chessells, J, Vargha-Khadem, F, Neville, B G
Fourteen children who relapsed after initial remission of leukaemia were studied. Six received a second course of cranial radiotherapy, while the remaining eight children were given total body...
Christie, D, Leiper, A D, Chessells, J M, Vargha-Khadem, F
Cognitive outcome, as measured by verbal and performance IQs, was compared in 35 girls and 47 boys who were in first remission for acute lymphoblastic leukaemia. All children had received...
Leiper, A D, Grant, D B, Chessells, J M
Testicular function was investigated by the luteinising hormone releasing hormone (LHRH) test and a three day human chorionic gonadotrophin (HCG) test in 11 prepubertal boys with acute lymphoblastic...
Gonadal function after testicular radiation for acute lymphoblastic leukaemia.
Leiper, A D, Grant, D B, Chessells, J M
Pubertal maturation, growth, and gonadal function were assessed in 13 boys with acute lymphoblastic leukaemia who had received direct testicular irradiation three to nine years earlier as treatment...
Acute lymphoblastic leukaemia under 2 years.
Presenting features and natural history were assessed in 48 children with acute lymphoblastic leukaemia less than 2 years of age at diagnosis. Of these, 16 were less than 1 year (group 1) and 32 were...
Chessells, J M, Leiper, A D, Tiedemann, K, Hardisty, R M, Richards, S
It has been postulated that variations in methotrexate absorption may influence the outcome of treatment in lymphoblastic leukaemia. One hundred and forty four children with acute lymphoblastic...
Precocious and premature puberty associated with treatment of acute lymphoblastic leukaemia.
Leiper, A D, Stanhope, R, Kitching, P, Chessells, J M
Early puberty in 28 children (23 girls, five boys) treated for acute lymphoblastic leukaemia (ALL) at a mean age of 4.0 years (range 1.4-7.8) is described. All but one had received prophylactic...
Papadimitriou, A, Urena, M, Hamill, G, Stanhope, R, Leiper, A D
Growth hormone was given to 13 children (nine boys, four girls) with acute leukaemia who had undergone treatment with cyclophosphamide and total body irradiation before bone marrow transplantation....
Impaired pubertal growth in acute lymphoblastic leukaemia.
Uruena, M, Stanhope, R, Chessells, J M, Leiper, A D
The growth of 182 patients who were long term survivors of childhood acute lymphoblastic leukaemia was retrospectively analysed. All remained in first remission and were treated with either 1800 or...