A. F. Geczy

Persistence of HLA-B27 cross-reactive bacteria in bowel flora of patients with ankylosing spondylitis.

Prendergast, J K, McGuigan, L E, Geczy, A F, Kwong, T S, Edmonds, J P

Previous studies have shown that antisera raised in rabbits to certain enteric bacteria (cross-reactive bacteria) are capable of specifically lysing in a 51chromium-release lymphocytotoxicity test...

Persistence of HLA-B27 cross-reactive bacteria in bowel flora of patients with ankylosing spondylitis.

Prendergast, J K, McGuigan, L E, Geczy, A F, Kwong, T S, Edmonds, J P

Previous studies have shown that antisera raised in rabbits to certain enteric bacteria (cross-reactive bacteria) are capable of specifically lysing in a 51chromium-release lymphocytotoxicity test...

Distribution of a contact sensitizer, 1-fluoro-2, 4-dinitrobenzene, in the tissues of the guinea-pig

Geczy, A. F., Baumgarten, A.

The distribution of tritiated 1-fluoro-2,4-dinitrobenzene (DNFBT) in the tissues was investigated after topical application to, or injection in, the skin of the guinea-pig. The elimination of the...

Antibodies to guinea-pig lymphokines: V. Suppression of normal lymphocyte transfer, immune lymphocyte transfer and direct reactions in the guinea-pig by anti-lymphokine globulin

Hentges, F., Geczy, Carolyn L., Geczy, A. F., De Weck, A. L.

An antiserum (anti-lymphokine globulin, ALkG) directed against highly-purified products of activated lymphocytes, inhibits normal lymphocyte transfer (NLT), immune lymphocyte transfer (ILT) and...

Genetic control of allogeneic interactions in the guinea-pig. V. Evidence for a dissociation between genes coding for A GPLA-B region-controlled determinant and genes coding for MLC suppressor cells.

Geczy, A F, Coulits, N

The genetic basis of guinea-pig leucocyte antigen (GPLA)-B.2-associated unresponsiveness in the guinea-pig mixed leucocyte culture (MLC) was investigated using fibroblasts as stimulating cells....

A factor in the culture filtrate of some Klebsiella isolates specifically modifies the fibroblasts of HLA-B27-positive normal individuals.

Rayment, C, Geczy, A F, Bashir, H V, Edmonds, J P

Cultured skin fibroblasts of HLA-B27-positive clinically normal individuals specifically bind, and are modified by, a factor in the culture filtrate of some Klebsiella isolates. These modified...

Lymphocyte transformation in contact sensitivity

Geczy, A. F., Baumgarten, A.

Leucocyte suspensions containing 97–100 per cent lymphocytes were prepared from the peripheral blood of unsensitized guinea-pigs as well as animals previously sensitized with...

Induction of delayed hypersensitivity by dinitrophenylated lymphocytes

Baumgarten, A., Geczy, A. F.

Erythrocytes, serum proteins and both living and killed lymphocytes from the peripheral blood of guinea-pigs were dinitrophenylated and then injected intraperitoneally into either the donor or other...

Genetic control of allogeneic interactions in the guinea-pig. IV. The specific elimination of MLC suppressor cells by the in vivo administration of antisera against a GPLA-B region-controlled determinant.

Geczy, A F, Coulits, N

The in vivo effects of alloantisera, on the production of mixed leucocyte culture (MLC)-suppressor cells and suppressor factor (MLC-SF) as well as on the adoptive transfer of MLC suppression, were...

HLA-B27 associated cross-reactive marker on the cells of New Zealand patients with ankylosing spondylitis.

McGuigan, L E, Geczy, A F, Prendergast, J K, Edmonds, J P, Hart, H H, Bashir, H V

We have previously shown that antibodies raised in rabbits to certain enteric bacteria will specifically lyse, in a 51Cr release assay, the peripheral blood lymphocytes (PBL) of 80% of HLA-B27...

Significance of non-pathogenic cross reactive bowel flora in patients with ankylosing spondylitis.

McGuigan, L E, Prendergast, J K, Geczy, A F, Edmonds, J P, Bashir, H V

We have previously shown that antisera raised in rabbits to certain enteric cross reactive strains of bacteria are capable of specifically lysing the peripheral blood lymphocytes of HLA-B27 positive...

A factor shed by lymphoblastoid cell lines of HLA-B27 positive patients with ankylosing spondylitis, specifically modifies the cells of HLA-B27 positive normal individuals.

Orban, P, Sullivan, J S, Geczy, A F, Upfold, L I, Coulits, N, Bashir, H V

Epstein-Barr virus transformed lymphoblastoid cell lines from HLA-B27 positive individuals with ankylosing spondylitis (B27+AS+) release, into the culture medium, a factor capable of specifically...

The distribution of a specific HLA-B27-associated cell surface component on the tissues of patients with ankylosing spondylitis.

Alexander, K, Edwards, C, Misko, I S, Geczy, A F, Bashir, H V, Edmonds, J P

In this paper, we report the presence on Epstein-Barr virus-transformed lymphoblastoid cell lines on platelets and on fibroblasts of an HLA-B27-associated cell surface complex (antigenically related...

A vaccine conjugate of 'ISCAR' immunocarrier and peptide epitopes of the E7 cervical cancer-associated protein of human papillomavirus type 16 elicits specific Th1- and Th2-type responses in immunized mice in the absence of oil-based adjuvants.

Tindle, R W, Croft, S, Herd, K, Malcolm, K, Geczy, A F, Stewart, T, ...

TraT protein, known as ISCAR (= Immunostimulatory Carrier), is one of a family of integral membrane proteins (Imps) of Escherichia coli representing powerful carrier molecules which when injected...

The modification of HLA-B27-positive lymphocytes by the culture filtrate of Klebsiella K43 BTS 1 is a metabolically active process.

Sullivan, J S, Geczy, A F

The culture filtrate of some bacteria contains a modifying factor which specifically interacts with the cells of HLA-B27-positive normal individuals (BS+ AS-); this modification results in a...