Ethanol acceptance as a function of genotype amounts of brain [Met]enkephalin.
Blum, K, Elston, S F, DeLallo, L, Briggs, A H, Wallace, J E
Our results indicate a negative correlation between the amount of ethanol (10%) consumed and endogenous levels of brain [Met]enkephalin in C57BL/6J (alcohol-preferring) and DBA/2J...
Management of urinary tract infection in general practice: a cost-effectiveness analysis.
Fenwick, E A, Briggs, A H, Hawke, C I
BACKGROUND: Symptoms associated with urinary tract infection (UTI) are common in women in general practice and represent a significant burden for the National Health Service. There is considerable...
Ethanol acceptance as a function of genotype amounts of brain [Met]enkephalin.
Blum, K, Elston, S F, DeLallo, L, Briggs, A H, Wallace, J E
Our results indicate a negative correlation between the amount of ethanol (10%) consumed and endogenous levels of brain [Met]enkephalin in C57BL/6J (alcohol-preferring) and DBA/2J...
Management of urinary tract infection in general practice: a cost-effectiveness analysis.
Fenwick, E A, Briggs, A H, Hawke, C I
BACKGROUND: Symptoms associated with urinary tract infection (UTI) are common in women in general practice and represent a significant burden for the National Health Service. There is considerable...
Briggs, A. H., Sculpher, M. J., Logan, R. P., Aldous, J., Ramsay, M. E., Baron, J. H.
OBJECTIVE--To assess the cost effectiveness of screening for and eradicating Helicobacter pylori in patients under 45 years of age presenting with dyspepsia. DESIGN--A decision analytic model...
Briggs, A.H., O'Brien, B.J., Blackhouse, G.
As many more clinical trials collect economic information within their study design, so health economics analysts are increasingly working with patient-level data on both costs and effects. In this...
Briggs, A.H., Goeree, R., Blackhouse, G., O'Brien, B.J.
When choosing between mutually exclusive treatment options, it is common to construct a cost-effectiveness frontier on the cost-effectiveness plane that represents efficient points from among the...
The death of cost-minimization analysis?
Four different types of evaluation methods, cost-benefit analysis (CBA), cost-utility analysis (CUA), cost-effectiveness analysis (CEA) and cost-minimization analysis (CMA), are usually...
No abstract available.
Briggs, A.H., Lozano-Ortega, G., Spencer, S., Bale, G., Spencer, M.D., Burge, S.
Objectives: To explore the cost-effectiveness of fluticasone propionate (FP) for the treatment of chronic obstructive pulmonary disease (COPD), we estimated costs and quality-adjusted life-years...
Parametric modelling of cost data: some simulation evidence
Briggs, A.H., Nixon, R., Dixon, S., Thompson, S.
Recently, commentators have suggested that the distributional form of cost data should be explicitly modelled to gain efficiency in estimating the population mean. We perform a series of simulation...
Statistical approaches to handling uncertainty in health economic evaluation
Not so long ago, uncertainty in economic evaluation was handled almost exclusively using simple one-way sensitivity analysis methods whereby individual parameters of an analysis were varied...
Cost-effectiveness acceptability curves in the dock: case not proven?
No abstract available.
Mihaylova, B., Briggs, A.H., Armitage, J., Parish, S., Gray, A., Collins, R.
Objectives: To evaluate the cost effectiveness of 40 mg simvastatin daily continued for life in people of different ages with differing risks of vascular disease. Design A model developed from a...
Briggs, A.H., Spencer, M., Wang, H., Mannino, D.
Background: Chronic obstructive pulmonary disease (COPD) is a debilitating and progressive disease. The severity of the condition has typically been characterized by a single physiological...
Campbell, H., Briggs, A.H., Buxton, M., Kim, L., Thompson, S.
Objectives: To review health economic models of population screening for abdominal aortic aneurysm (AAA) among elderly males and assess their credibility for informing decision-making. Methods: A...
Probabilistic sensitivity analysis for NICE technology assessment: not an optional extra
Claxton, K., Sculpher, M., McCabe, C., Briggs, A.H., Akehurst, R., Buxton, M., ...
Recently the National Institute for Clinical Excellence (NICE) updated its methods guidance for technology assessment. One aspect of the new guidance is to require the use of probabilistic...
Cost-effectiveness of asthma control: an economic appraisal of the GOAL study
Briggs, A.H., Bousquet, J., Wallace, M.V., Busse, W.W., Clark, T.J.H., Pedersen, S.E., ...
Background: The Gaining Optimal Asthma ControL (GOAL) study has shown the superiority of a combination of salmeterol/fluticasone propionate (SFC) compared with fluticasone propionate alone (FP) in...
Wu, O., Briggs, A.H., Dutton, S., Hirst, A., Maresh, M., Nicholson, A., ...
Objectives To evaluate the relative cost-effectiveness of uterine artery embolisation (UAE) and hysterectomy in women with symptomatic uterine fibroids from the perspective of the UK NHS. Design...
Reed, S.D., Dillingham, P.W., Briggs, A.H., Veestra, D.L., Sullivan, S.D.
Pharmacy and therapeutics committees commonly cite a lack of generalizability as a reason for not incorporating cost-effectiveness information into decision making. To address this concern, many...
A Bayesian approach to stochastic cost-effectiveness analysis
The aim of this paper is to discuss the use of Bayesian methods in cost-effectiveness analysis (CEA) and the common ground between Bayesian and traditional frequentist approaches. A further aim is to...
Affordability and cost-effectiveness: decision-making on the cost-effectiveness plane
Much recent research interest has focused on handling uncertainty in cost-effectiveness analysis and in particular the calculation of confidence intervals for incremental cost-effectiveness ratios...
Cost-effectiveness analysis is now an integral part of health technology assessment and addresses the question of whether a new treatment or other health care program offers good value for money. In...
Manca, A., Rice, N., Sculpher, M.J., Briggs, A.H.
Cost-effectiveness analysis (CEA) in health care is increasingly conducted alongside multicentre and multinational randomised controlled clinical trials (RCTs). The increased use of stochastic CEA is...