A. Heerschap

Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies (2006)

Kemper, E.M., Leenders, W., Kusters, B., Lyons, S., Buckle, T., Heerschap, A., ...

The blood-brain barrier (BBB) is considered one of the major causes for the low efficacy of cytotoxic compounds against primary brain tumours. The aim of this study was to develop intracranial tumour...

Modulation of Hypoxia in Murine Liver Metastases of Colon Carcinoma by Nicotinamide and Carbogen (2005)

J. Bussink, J. Lok, I. Verhagen, A. Heerschap, ...

van Laarhoven, H. W. M., Bussink, J., Lok, J., Verhagen, I., Punt, C. J. A., Heerschap, A., Kaanders, J. H. A. M. and van der Kogel, A. J. Modulation of Hypoxia in Murine Liver Metastases of Colon...

Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy (2005)

Figdor, C.G., Heerschap, A., Punt, C.J.A., Scheenen, T.W.J., Bulte, J.W.M., Adema, G.J., ...

Glycogen synthesis in human gastrocnemius muscle is not representative of whole-body muscle glycogen synthesis (2005)

Serlie, M.J.M., Haan, J.H., Tack, C.J., Verberne, H.J., Ackermans, M.T., Heerschap, A., ...

Measurements of T1 and T2 relaxation times of colon cancer metastases in rat liver at 7 T [online ?] (2004)

Gambarota, G., Veltien, A., Laarhoven, H. Van, Phillippens, M., Jonker, A., Mook, O.R.F., ...

Combined quantitative dynamic contrast-enhanced MR imaging and (1)H MR spectroscopic imaging of human prostate cancer (2004)

Dorsten, F.A. Van, Graaf, M Van Der, Engelbrecht, M.R., Leenders, G.J. Van, Verhofstad, A, Rijpkema, M, ...

Sjogren-Larsson syndrome: clinical and MRI/MRS findings in FALDH-deficient patients (1999)

Rotteveel, J., Thijssen, H.O.M., Heerschap, A., ...

1H NMR spectroscopy of body fluids in patients with inborn errors of purine and pyrimidine metabolism (1997)

Wevers, R., Engelke, U., Rotteveel, J., Heerschap, A., ...

Use of gene targeting for compromising energy homeostasis in neuromuscular tissues : the role of sarcomeric mitochondral creatine kinase (1997)

Wieringa, B., Jap, P.H.K., Koudijs, J.C.M., Brückwilder, M.L.P., Pette, D., Perryman, B., ...

Muscle glycogen recovery after exercise during glucose and fuctose intake monitored by 13C-NMR (1997)

Hopman, M.T.E., Oeseburg, B., Rehrer, N.J., Heerschap, A., Houtman, S., ...

NMR perfusion and metabolic imaging and some examples on brain tumours (1997)

Heerschap, A., Rozijn, T.H.

NMR-spectroscopy in fatigue two distinct pH-levels in the tibialis anterior muscle (1997)

Stegeman, D.F., Wevers, R.A., Heerschap, A., Houtman, C.J.

NMR-spectroscopy in fatigue-two distinct pH-levels in the tibialis anterior muscle (1997)

Stegeman, D.F., Wevers, R.A., Heerschap, A., Houtman, C.J.

Altered Ca2+ Responses in Muscles with Combined Mitochondrial and Cytosolic Creatine Kinase Deficiencies (1997)

Wieringa, B., Veerkamp, J.H., Jap, P.H.K., Koudijs, J.C.M., Brückwilder, M.L.P., Pette, D., ...

Post-Ischemic 31P NMR determination of myocardial intracellular pH IN VIVO using ATP Peak (1997)

Oeseburg, B., Verheugt, F.W.A., Skotnicki, S.H., Heerschap, A., Houston, R.J.F.

Proton MR Spectroscopy of the Normal Human Prostate with an Endorectal Coil and a Double Spin-Echo Pulse Sequence (1997)

Ruijs, J.H.J., Barentsz, J.O., Graaf, M. Van Der, Jager, G.J., Heerschap, A.

An animal model to investigate cerebral metabolism of fetal lambs in utero during hypoxia by nuclear magnetic resonance spectroscopy (1997)

Oeseburg, B., Nijland, R., Crevels, A.J., Nijhuis, J.G., Heerschap, A., ...

An animal model to investigate cerebral metabolism of fetal lambs in utero during hypoxia by nuclear magnetic resonance spectroscopy (1997)

Oeseburg, B., Asten, J. Van, Nijland, R., Crevels, J., Nijhuis, J.G., Heerschap, A., ...

Removal of the outer lines of the citrate multiplet in proton magnetic resonance spectra of the prostatic gland by accurate timing of a point-resolved spectroscopy pulse sequence (1997)

Heerschap, A., Jager, G.J.

Use of gene targeting for compromising energy homeostasis in neuro-muscular tissues: the role of sarcomeric mitochondrial creatine kinase (1997)

Wieringa, B., Jap, P.H.K., Koudijs, J.C.M., Brückwilder, M.L.P., Pette, D., Perryman, B., ...

1H NMR spectroscopy of body fluids in patients with inborn errors of purine and pyrimide metabolism. (1997)

Heerschap, A., Rotteveel, J.J., ...

H-Magnetic resonance spectroscopy; a new technique to discriminate benign and malignant tumors (1997)

Wevers, R., Heerschap, A., Massuger, L.

Atpcontennt measured by 31P NMR correlates with post-ischaemic recovery of external work output in anisolated rat heart perfused with erythrocyte suspension. (1997)

Oeseburg, B., Verheugt, F.W.A., Skotnicki, S.H., Heerschap, A., Houston, R.J.F.

1hnmr spectroscopy of body fluids in patients with inborn errors of purine and pyrimidine metabolism (1997)

Heerschap, A., Rotteveel, J.J., ...

Cerebral lactate of hypoxic fetal lambs measured by 1H-NMR spectroscopy (1997)

Nijhuis, J.G., Jongsma, H.W., Heerschap, A.

Cerebral lactate of hypoxic fetal lambs measured by 1H-NMR sppectroscopy (1997)

Nijhuis, J.G., Jongsma, H.W., Heerschap, A.

Coronary flow response after myocardial ischemia may predict level of functional recovery. (1997)

Oeseburg, B., Heerschap, A., Skotnicki, S.H., Houston, R.J.F.

Ejecting isolated rat heart model perfused with erythrocyte suspension for NMR assessment of cardioprotective techniques: 31P NMR profile of global ischemia (1997)

Oeseburg, B., Verheugt, F.W.A., Skotnicki, S.H., Heerschap, A., Klinkenberg, T.J., Houston, R.J.F.

Essential improvements to a working, isolated rat heart model with hemodynamic and NMR spectroscopic monitoring (1997)

Oeseburg, B., Verheugt, F.W.A., Heerschap, A., Skotnicki, S.H., Houston, R.J.F.

Euglycemic-hyperinsulinemic clamp in healthy volunteers and insulin-resistant obese subjects monitored with in vivo 13C-MR spectroscopy (1997)

Heerschap, A., Smits, P., Tack, C.J.J.

Fast dynamic MR imaging and magnetic resonance spectroscopy in the characterization of adnexal tumors (1997)

Heerschap, A., Wevers, R.A., Barentsz, J.O.

In Vivo Proton MR Spectroscopy Reveals Altered Metabolite Content in Malignant Prostate Tissue (1997)

Ruijs, J.H.J., Ruijter, T.E.G., Oosterhof, G.O.N., Barentsz, J.O., ...

In vivo 31P magnetic resonance spectroscopy and morphometric analysis of the perfused vascular architecture of human glioma xenografts in nude mice (1997)

Heerschap, A.

Invivoproroton MR spectroscopy reveals altered metabolite content in malignant prostate tissue (1997)

Ruijs, S.H.J., Ruijter, T.E.G., Oosterhof, G.O.N., Barentsz, J.O., ...

Essential improvements to a working, isolated rat heart model with hemodynamic and NMR spectroscopic monitoring (1997)

Oeseburg, B., Verheugt, F.W.A., Heerschap, A., Skotnicki, S.H., Houston, R.J.F.

5-Fluorouracil metabolite patterns in viable and necrotic tumor areas of murine colon carcinoma determined by in vitro 19F NMR spectroscopy. (1996)

Kamm, Y.J.L., Heerschap, A., Rosenbusch, G., Vervoort, J., Wagner, D.J.T.

Muscle glycogen recovery after exercise during glucose and fructose intake monitored by C13NMR (1996)

Hopman, M.T.E., Oeseburg, B., Rehrer, N.J., Heerschap, A., Houtman, S., ...

Proton magnetic resonance spectroscopy in patients with glial tumors: a multicenter study (1996)

Zimmerman, R.A., Wicklow, K., Vogl, T.J., Terwey, B., Stillman, A.E., Spraggins, T.A., ...

1H-NMR Spectroscopy in Body Fluids and Leucocytes: a view on Metabolism (1996)

Heerschap, A., Engelke, U.F.H., Wevers, R.A.

5-Fluorouracil metabolite patterns in viable and necrotic tumor areas of murine colon carcinoma determined by 19F NMR spectroscopy (1996)

Wagener, D.J.T., Vervoort, J., Rosenbusch, G., Heerschap, A., Kamm, Y.J.L.

Effect of cation binding on the proton chemical shifts and the spin-spin coupling constant of citrate (1996)

Heerschap, A.

Muscle glycogen recovery after exercise during glucose and fructose intake monitored by C-13-NMR (1996)

Hopman, M.T.E., Oeseburg, B., VanDenBoogert, H.J., Rehrer, N.J., Heerschap, A., Houtman, S., ...

1H-NMR Spectroscopie in lichaamsvloeistoffen en leucocyten (1995)

Heerschap, A., Engelke, U.F.H., Wevers, R.A.

Localized Proton NMR spectroscopy in the striatum of patients with idiopathic Parkinson's disease: a multicenter pilot study (1995)

Tosk, J., Koster, A. De, Rinne, U.K., Masur, H., Heerschap, A., Vermathen, P., ...

1H-NMR spectroscopie in lichaamsvloeistoffen en leucocyten (1995)

Heerschap, A., Engelke, U.F.H., Wevers, R.A.

Sample choice and sample preparation for 1H-NMR spectroscopy for diagnosing inborn errors of metabolism. (1995)

Heerschap, A., Engelke, U.F.H., Wevers, R.A.

Standardized method for high-resolution 1H-NMR of cerebrospinal fluid (1995)

Heerschap, A., Gabreëls, F.J.M., Wendel, U.A.H., Engelke, U.F.H., Wevers, R.A.

Standardized method for high-resolution 1H-NMR of cerebrospinal fluid. (1995)

Heerschap, A., Gabreëls, F.J.M., Wendel, U.A.H., Engelke, U.F.H., Wevers, R.A.

The effect of successive high-energy shock wave tumor administration on tumor blood flow (1995)

Oosterhof, G.O.N., Schalken, J.A., Heerschap, A., Debruyne, F.M.J., Cornel, E.B.

The effects of successive high-energy shock-wave tumor administration on tumor blood flow (1995)

Oosterhof, G.O.N., Schalken, J.A., Heerschap, A., Debruyne, F.M.J., Cornel, E.B.

Diagnosis of a new case of trimethylaminuria using direct proton NMR analysis of urine (1995)

Wevers, R.A., Engelke, U.F.H., Heerschap, A., Bakker, H.

Diagnosis of a new case of trimethylaminuria using direct proton NMR spectrocopy of urine (1995)

Wevers, R.A., Engelke, U.F.H., Heerschap, A., Bakker, H., Abeling, A.

Diagnosis of a new case of trimethylaminuria using direct proton NMR spectroscopy of urine (1995)

Wevers, R.A., Engelke, U.F.H., Heerschap, A., Bakker, H.

A standarized method for high resolution 1 H NMR spectroscopy of cerbrospinal fluid for neurometabolic studies (1995)

Heerschap, A., Gabreëls, F.J.M., Wendel, U.A.H., Engelke, U.F.H., Wevers, R.A.

In vitro proton magnetic resonance spectroscopy of four human prostate cancer cell lines (1995)

Schalken, J.A., Debruyne, F.M.J., Heerschap, A., Oosterhof, G.O.N., Ruijter, J.E. De, ...

Effect of modulators on 5-fluorouracil metabolite patterns in murine colon carcinoma as determined by in vitro 19F NMR spectroscopy. (1994)

Kamm, Y.J.L., Vervoort, J., Heerschap, A., Wagener, T.J.Th.

Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression.

Van Deursen, J, Ruitenbeek, W, Heerschap, A, Jap, P, Ter Laak, H, Wieringa, B

To understand better the role of the creatine kinase (CK)/phosphocreatine system in muscle bioenergetics, a series of mouse mutants with subnormal muscle CK (M-CK) expression has been generated. Here...

Nuclear magnetic resonance studies on yeast tRNAPhe. II. Assignment of the iminoproton resonances of the anticodon and T stem by means of nuclear Overhauser effect experiments at 500 MHz.

Heerschap, A, Haasnoot, C A, Hilbers, C W

Resonances of the water exchangeable iminoprotons of the T and anticodon stem of yeast tRNAPhe were assigned by means of Nuclear Overhauser Effects (NOE's). Together with our previous assignments of...

Nuclear magnetic resonance studies on yeast tRNAPhe. III. Assignments of the iminoproton resonances of the tertiary structure by means of nuclear Overhauser effect experiments at 500 MHz.

Heerschap, A, Haasnoot, C A, Hilbers, C W

Resonances of the water exchangeable iminoprotons of the tertiary structure of yeast tRNAPhe were studied by experiments involving Nuclear Overhauser Effects (NOE's). Direct NOE evidence is presented...

Nuclear magnetic resonance studies on yeast tRNAPhe I. Assignment of the iminoproton resonances of the acceptor and D stem by means of Nuclear Overhauser Effect experiments at 500 MHz.

Heerschap, A, Haasnoot, C A, Hilbers, C W

Resonances of the water exchangeable iminoprotons of the acceptor and D stem of yeast tRNAPhe have been assigned by means of Nuclear Overhauser Effects (NOE's). Assignments were made for spectra...

Influence of the polyamines spermine and spermidine on yeast tRNAPhe as revealed from its imino proton NMR spectrum.

Heerschap, A, Walters, J A, Hilbers, C W

A comparison of imino proton NMR spectra of yeast tRNAPhe recorded at various solution conditions indicates, that polyamines have a limited effect on the structure of this tRNA molecule. Polyamines...

Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression.

Van Deursen, J, Ruitenbeek, W, Heerschap, A, Jap, P, Ter Laak, H, Wieringa, B

To understand better the role of the creatine kinase (CK)/phosphocreatine system in muscle bioenergetics, a series of mouse mutants with subnormal muscle CK (M-CK) expression has been generated. Here...

Nuclear magnetic resonance studies on yeast tRNAPhe. II. Assignment of the iminoproton resonances of the anticodon and T stem by means of nuclear Overhauser effect experiments at 500 MHz.

Heerschap, A, Haasnoot, C A, Hilbers, C W

Resonances of the water exchangeable iminoprotons of the T and anticodon stem of yeast tRNAPhe were assigned by means of Nuclear Overhauser Effects (NOE's). Together with our previous assignments of...

Nuclear magnetic resonance studies on yeast tRNAPhe. III. Assignments of the iminoproton resonances of the tertiary structure by means of nuclear Overhauser effect experiments at 500 MHz.

Heerschap, A, Haasnoot, C A, Hilbers, C W

Resonances of the water exchangeable iminoprotons of the tertiary structure of yeast tRNAPhe were studied by experiments involving Nuclear Overhauser Effects (NOE's). Direct NOE evidence is presented...

Nuclear magnetic resonance studies on yeast tRNAPhe I. Assignment of the iminoproton resonances of the acceptor and D stem by means of Nuclear Overhauser Effect experiments at 500 MHz.

Heerschap, A, Haasnoot, C A, Hilbers, C W

Resonances of the water exchangeable iminoprotons of the acceptor and D stem of yeast tRNAPhe have been assigned by means of Nuclear Overhauser Effects (NOE's). Assignments were made for spectra...

Influence of the polyamines spermine and spermidine on yeast tRNAPhe as revealed from its imino proton NMR spectrum.

Heerschap, A, Walters, J A, Hilbers, C W

A comparison of imino proton NMR spectra of yeast tRNAPhe recorded at various solution conditions indicates, that polyamines have a limited effect on the structure of this tRNA molecule. Polyamines...

Presence of (phospho)creatine in developing and adult skeletal muscle of mice without mitochondrial and cytosolic muscle creatine kinase isoforms

Renema, W K J, Klomp, D W J, Wieringa, B, ...

We assessed the relationship between phosphocreatine (PCr) and creatine (Cr) content and creatine kinase (CK) activity in skeletal muscle of mice. The PCr and total Cr (tCr) concentrations, as well...