A. Houdusse

Three conformational states of scallop myosin S1

Houdusse, A., Szent-Györgyi, A. G., Cohen, C.

We have determined the structure of the intact scallop myosin head, containing both the motor domain and the lever arm, in the nucleotide-free state and in the presence of MgADP⋅VO4, corresponding...

Target sequence recognition by the calmodulin superfamily: implications from light chain binding to the regulatory domain of scallop myosin.

Houdusse, A, Cohen, C

Some of the rules for how members of the calmodulin (CaM) superfamily bind to target peptides are revealed by the crystal structure of the regulatory domain of scallop myosin. The structure shows...

Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.

Chitarra, V, Alzari, P M, Bentley, G A, Bhat, T N, Eiselé, J L, Houdusse, A, ...

Although antibodies are highly specific, cross-reactions are frequently observed. To understand the molecular basis of this phenomenon, we studied the anti-hen egg lysozyme (HEL) monoclonal antibody...

Three conformational states of scallop myosin S1

Houdusse, A., Szent-Györgyi, A. G., Cohen, C.

We have determined the structure of the intact scallop myosin head, containing both the motor domain and the lever arm, in the nucleotide-free state and in the presence of MgADP⋅VO4, corresponding...

Target sequence recognition by the calmodulin superfamily: implications from light chain binding to the regulatory domain of scallop myosin.

Houdusse, A, Cohen, C

Some of the rules for how members of the calmodulin (CaM) superfamily bind to target peptides are revealed by the crystal structure of the regulatory domain of scallop myosin. The structure shows...

Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.

Chitarra, V, Alzari, P M, Bentley, G A, Bhat, T N, Eiselé, J L, Houdusse, A, ...

Although antibodies are highly specific, cross-reactions are frequently observed. To understand the molecular basis of this phenomenon, we studied the anti-hen egg lysozyme (HEL) monoclonal antibody...

Allosteric Communication in Myosin V: From Small Conformational Changes to Large Directed Movements

Cecchini, M., Houdusse, A., Karplus, M.

The rigor to post-rigor transition in myosin, a consequence of ATP binding, plays an essential role in the Lymn–Taylor functional cycle because it results in the dissociation of the actomyosin...