Human Fc gamma RII, in the absence of other Fc gamma receptors, mediates a phagocytic signal.
Indik, Z, Kelly, C, Chien, P, Levinson, A I, Schreiber, A D
Fc gamma receptors are important components in the binding and phagocytosis of IgG-sensitized cells. Studies on the role of these receptors have been limited by the fact that most hematopoietic cells...
Levinson, A I, Dziarski, A, Zweiman, B, Dziarski, R
Staphylococcal cell wall products have been widely examined as probes for dissection of in vitro human immune responses. Mitogenic and polyclonal B-cell-activating properties have been attributed to...
Staphylococcus aureus Cowan I. Potent stimulus of immunoglobulin M rheumatoid factor production.
Levinson, A I, Tar, L, Carafa, C, Haidar, M
These studies demonstrate that Staphylococcus aureus Cowan I (SAC), a protein A-positive Staphylococcal strain, is a potent and consistent inducer of IgM rheumatoid factor production by normal human...
Human Fc gamma RII, in the absence of other Fc gamma receptors, mediates a phagocytic signal.
Indik, Z, Kelly, C, Chien, P, Levinson, A I, Schreiber, A D
Fc gamma receptors are important components in the binding and phagocytosis of IgG-sensitized cells. Studies on the role of these receptors have been limited by the fact that most hematopoietic cells...
Levinson, A I, Dziarski, A, Zweiman, B, Dziarski, R
Staphylococcal cell wall products have been widely examined as probes for dissection of in vitro human immune responses. Mitogenic and polyclonal B-cell-activating properties have been attributed to...
Staphylococcus aureus Cowan I. Potent stimulus of immunoglobulin M rheumatoid factor production.
Levinson, A I, Tar, L, Carafa, C, Haidar, M
These studies demonstrate that Staphylococcus aureus Cowan I (SAC), a protein A-positive Staphylococcal strain, is a potent and consistent inducer of IgM rheumatoid factor production by normal human...
Reactive and non-reactive lymphocytes in experimental allergic encephalomyelitis.
Levinson, A I, Lisak, R P, Zweiman, B, Wilkerson, L D
Myelin basic protein (BP),induces an increased in vitro proliferative response of peritoneal exudate cells (PEC), compared with that given by pheripheral blood lymphocytes (PBL), in guinea-pigs with...
Effect of PHA-activated T cells on B-cell differentiation.
Recent studies indicate that human T cells expressing the T4 determinant are comprised of functionally distinct subsets. We investigated if activation of OKT4+ cells with the mitogen PHA affected...
Schreiber, A D, Kelley, M, Dziarski, A, Levinson, A I
Human monocytes subserve many roles in the immune response. It is not clear, however, whether this functional heterogeneity reflects the action of different monocyte subpopulations. We separated...
The immunohistology of the thymus in myasthenia gravis.
Kornstein, M. J., Brooks, J. J., Anderson, A. O., Levinson, A. I., Lisak, R. P., Zweiman, B.
We have investigated cell subpopulations in frozen sections of thymus tissue obtained from myasthenic (MG) and control subjects. With the use of an avidin-biotin immunoperoxidase system with...
Pardo, I, Carafa, C, Dziarski, R, Levinson, A I
To gain insight into possible determinants of in vivo polyclonal B cell activation seen in rheumatoid arthritis (RA), we enumerated immunoglobulin secreting cells appearing in cultures of peripheral...
Modulation of polyclonal B cell differentiation by human leucocyte alpha interferon.
Levinson, A I, Dziarski, A, Hooks, J J
Although interferon (IFN) profoundly affects immune responses in animals, less is known about its immunoregulatory activity in man. Therefore, peripheral blood mononuclear cells (PBM) from 20 healthy...
T and B lymphocytes in multiple sclerosis.
Lisak, R P, Levinson, A I, Zweiman, B, Abdou, N I
The percentage and total number of E and EAC rosettes, as indicators of T and B lymphocytes respectively, were studied in the blood of subjects with multiple sclerosis (MS) and normals. MS patients...
Levy, R J, Haidar, M, Park, H, Tar, L, Levinson, A I
The present studies were carried out to further characterize the polyclonal B cell activating properties of bacterial peptidoglycan (PG) and to determine if this ubiquitous agent induces in vitro IgM...
There has been considerable interest in defining the relationship between the expression of allergic and autoimmune diseases in populations of patients. Are patients with autoimmune disease...