Scientific Commons: A. J.

The limnological record of human impact on catchment land cover and on lake sedimentation during the historical period has been established for Pinto Lake in Central Coastal California. In addition,...

Holocene sea levels, Last Glacial Maximum glaciomarine environments and geophysical models in the northern Irish Sea Basin, UK (2006)

Roberts,
D.H,
Chiverell,
R.C.,
Innes,
J.B.,
...

Development of the enteric nervous system in relation to Hirschsprungs Disease (2006)

Young,
H.M.,
Newgreen,
D.F.,
Burns,
A.J.

Functional response to active and passive ankle movements with clinical correlations in patients with primary progressive multiple sclerosis (2006)

Ciccarelli,
O.,
Toosy,
A.T.,
Marsden,
J.F.,
...

Compulsive drug use linked to sensitized ventral striatal dopamine transmission. (2006)

Evans,
A.H.,
Pavese,
N.,
Lawrence,
A.D.,
...

Simultaneous contrast and white's effect as a consequence of a biologically plausible model of brightness filling-in [Abstract] (2006)

Ioannides,
A.,
Johnston,
A. J.,
Griffin,
L.

Mechano-electrical transduction: new insights into old ideas. (2006)

Ricci,
A.J.,
Kachar,
B.,
Gale,
J.,
...

Carbon Reduction in Buildings (CaRB) - Understanding the social and technical factors that influence energy use in UK buildings (2006)

Lomas,
K,
Oreszczyn,
T.,
Shipworth,
D.,
...

7-8 September 2006

Large Scale Energy Surveys in the UK Retail Sector (2006)

Brown,
N.,
Wright,
A.J.,
Caeiro,
J.A.,
...

7-8 September 2006

The Case for Joined-Up Research on Carbon Emissions from the Building Stock: adding value to household and building energy datasets (2006)

Summerfield,
A.J.,
Lowe,
R.J.,
Firth,
S.K.,
...

7-8 September 2006 To reach UK objectives for reducing carbon emissions, it is argued that joined-up research on energy use in buildings is essential to develop and support government policy...

Large Scale Energy Surveys in the UK Retail Sector (2006)

Brown,
N.,
Wright,
J.A.,
Caeiro,
J.A.J.,
...

The UK retail sector accounts for around 18% of total non-domestic UK building floor space and a significant proportion of UK energy use. Much of the information available about energy use was...

Aortic function is compromised in a rat model of polycystic ovary function (2006)

Lakhani,
K.,
Yang,
W.,
Dooley,
A.,
...

Enhanced porphyrin accumulation using dendritic derivatives of 5-aminolaevulinic acid for photodynamic therapy; an in vitro study (2006)

Battah,
S.,
O'Neill,
S.,
Edwards,
C.,
...

Generation of voxel phantoms to investigate the effect of statistical noise on image analysis programs (2006)

Green,
A.J.,
Begent.,
R.H.J.

Current prospects of adult stem cell-based therapies for ocular repair and regeneration. (2006)

Limb,
G.A.,
Daniels,
J.T.,
Cambrey,
A.D.,
...

Stem cell therapy delivery- treading the regulatory tightrope. (2006)

Daniels,
J.T.,
Secker,
G.A.,
Shortt,
A.J.,
...

Evolution ofthe Antarctic ice sheet: new understanding and challenges (2006)

Payne,
A.J.,
Hunt,
J.C.R.Hunt,
D.J. Wingham

Unravelling the multi-stage burial history of the Swiss Molasse Basin: integration of apatite fission track, vitrinite reflectance and biomarker isomerisation analysis (2006)

Mazurek,
M.,
Hurford,
A.J.,
Leu,
W.

A complex basin evolution was studied using various methods, including thermal constraints based on apatite fission-track (AFT) analysis, vitrinite reflectance (VR) and biomarker isomerisation, in...

CJD: update for dental staff (2006)

Scully,
C.,
Smith,
A.J.,
Bagg,
J.

DAS "CHARANGAS" ÀS TORCIDAS VIRTUAIS - A COMUNIDADE, OS MEIOS DE COMUNICAÇÃO E O FUTEBOL (2005)

ROCCO JúNIOR,
A.J

Trabalho apresentado no NP 18 - Comunicação e Esporte no XXVII Congresso Brasileiro de Ciências da Comunicação, Porto Alegre RS, 2004. O desenvolvimento...

"TODOS JUNTOS VAMOS, PRA FRENTE BRASIL" - O FUTEBOL, OS MEIOS DE COMUNICAÇÃO, O PÚBLICO E O PRIVADO (2005)

ROCCO JUNIOR,
A.J

Trabalho apresentado no NP18 - Comunicação e Esporte durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005....

Nonsense mutations in mitochondrial DNA associated with myalgia and exercise intolerance (2005)

Pulkes,
T.,
Liolitsa,
D.,
Wills,
A.J.,
...

Problems with botulinum toxin treatment in mitochondrial cytopathy: case report and review of the literature (2005)

Gioltzoglou,
T.,
Cordivari,
C.,
Lee,
P.J.,
...

The effects of urethritis on seminal plasma HIV-1 RNA loads in homosexual men not receiving antiretroviral therapy. (2005)

Sadiq,
S.T.,
Taylor,
S.,
Copas,
A.J.,
...

Is ritonavir boosting associated with gout? (2005)

Creighton,
S.,
Miller,
R.,
Edwards,
S.,
...

UK controlled trial of intrapleural streptokinase for pleural infection. First Multicentre Intrapleural Sepsis Trial (MIST1 Group). (2005)

Maskell,
N.A.,
Davies,
C.W.,
Nunn,
A.J.,
...

Progression of structural neuropathology in preclinical Huntington's disease: a tensor based morphometry study (2005)

Kipps,
C.M.,
Duggins,
A.J.,
Mahant,
N.,
...

Vibrational inelastic scattering effects in molecular electronics. (2005)

Ness,
H.,
Fisher,
A.J.

Adult attachment, alexithymia, and symptom reporting: an extension to the four category model of attachment (2005)

Wearden,
A.J.,
Lamberton,
N.,
Crook,
N.,
...

OBJECTIVE: A previous study using a three-category attachment model found that avoidant attachment was associated with increased symptom reporting, and that this relationship was largely mediated by...

Erythropoietin protects the myocardium against reperfusion injury in vitro and in vivo (2005)

Bullard,
A.J.,
Govewalla,
P.,
Yellon,
D.M.

Life course epidemiology: An alternative approach to the collection and analysis of carbon emission data (2005)

Summerfield,
A.J.,
Bruhns,
H.,
Caeiro,
J.A.J.,
...

Chronic erythropoietin treatment limits infarct-size in the myocardium in vitro. (2005)

Bullard,
A.J.,
Yellon,
D.M.

Parkinsonism and nigrostriatal dysfunction are associated with spinocerebellar ataxia type 6 (SCA6) (2005)

Khan,
N.L.,
Giunti,
P.,
Sweeney,
M.G.,
...

UCHL-1 gene in multiple system atrophy: A haplotype tagging approach (2005)

Healy,
D.G.,
Abou-Sleiman,
P.M.,
Quinn,
N.,
...

ALK positive inflammatory myofibroblastic tumour of the pineal region (2005)

Clarke,
A.J.,
Jacques,
T.S.,
Galloway,
M.J.,
...

The H1c haplotype at the MAPT locus is associated with Alzheimer's disease (2005)

Myers,
A.J.,
Kaleem,
M.,
Marlowe,
L.,
...

Retinal nerve fiber layer axonal loss and visual dysfunction in optic neuritis (2005)

Trip,
S.A.,
Schlottmann,
P.G.,
Jones,
S.J.,
...

Transmission of systemic transthyretin amyloidosis by means of domino liver transplantation (2005)

Stangou,
A.J.,
Heaton,
N.D.,
Hawkins,
P.N.

Stimulated Emission Depletion Studies of Molecular Probe Dynamics (2005)

Marsh,
R.J.,
Leonczek,
N.D.,
Armoogum,
D.A.,
...

Multiple ionization of ions and atoms by intense ultrafast laser pulses (2005)

Suresh,
M.,
McKenna,
J.,
Srigengan,
B.,
...

Risks of gene therapy should be weighed against lack of alternatives for many diseases (2005)

MacLaren,
R.E.,
Ali,
R.R.,
Thrasher,
A.J.

Soluble adhesion molecules in Gilles de la Tourette's syndrome (2005)

Martino,
D.,
Church,
A.J.,
Defazio,
G.,
...

To investigate the immune-mediated response in TS, and its relationship with streptococcal infection, we measured serum levels of soluble intercellular adhesion molecule-1 (ICAM-1), vascular cell...

Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition (2005)

Bandopadhyay,
R.,
Kingsbury,
A.E.,
Muqit,
M.M.,
...

T cell suicide gene therapy to aid haematopoietic stem cell transplantation (2005)

Qasim,
W.,
Gaspar,
H.B.,
Thrasher,
A.J.

Graft versus host disease (GVHD) is a T cell mediated phenomenon that arises following allogeneic haematopoietic stem cell transplantation, and may be particularly severe in the context of human...

Abnormal KCNQ1 trafficking influences disease pathogenesis in hereditary long QT syndromes (LQT1) (2005)

Wilson,
A.J.,
Quinn,
K.V.,
Graves,
F.M.,
...

OBJECTIVE: In the hereditary long QT syndromes the commonest defect is in the K+ channel pore forming subunit, KCNQ1. In this study we investigated the role that abnormal KCNQ1 trafficking has in the...

Cognitive and behavioural outcome following haematopoietic cell transplantation for severe congenital immunodeficiencies (2005)

Titman,
P.S.,
Morton,
L.,
Skucek,
E.,
...

Effective Gene Therapy with Non-Integrating Lentiviral Vectors (2005)

Yanez,
R.J.,
Balaggan,
K.S.,
Smith,
A.J.,
...

Gene therapy for lympho-hematopoietic disorders (2005)

Thrasher,
A.J.,
Gaspar,
H.B.

Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy (2005)

Tschernutter,
M.,
Schlichtenbrede,
F.C.,
Howe,
S.,
...

The Royal College of Surgeons (RCS) rat is a well-characterized model of autosomal recessive retinitis pigmentosa (RP) due to a defect in the retinal pigment epithelium (RPE). It is homozygous for a...

True status of supplement not made clear to reader (2005)

Wright,
C.M.,
Waterston,
A.J.,
Cole,
T.J.,
...

Update on treatment of human SLID by somatic gene therapy (2005)

Thrasher,
A.J.

Comment on Hendriks et al.: Prognostic factors for poor recovery in acute whiplash patients. Pain 2005; 114: 408-416 (2005)

Wynne-Jones,
G.,
Jones,
G.T.,
Atherton,
K.,
...

Expression pattern of glypican-4 suggests multiple roles during mouse development (2005)

Ybot-Gonzalez,
P.,
Copp,
A.J.,
Greene,
N.D.E.

Glypicans are glycosylphosphatidylinositol-anchored heparan sulphate proteoglycans, which are thought to modulate signalling by growth factors, including fibroblast growth factors and Wnts. Studies...

Development of the enteric nervous system, smooth muscle and interstitial cells of Cajal in the human gastrointestinal tract (2005)

Wallace,
A.S.,
Burns,
A.J.

The generation of functional neuromuscular activity within the pre-natal gastrointestinal tract requires the coordinated development of enteric neurons and glial cells, concentric layers of smooth...

Enteral vancomycin to control MRSA (2005)

Van Saene,
H.K.F.,
Weir,
W.I.,
De La Cal,
M.A.,
...

Variables affecting kinetics of minimal residual disease clearance in children with lymphoblastic leukaemia; Results of the United Kingdom Medical Research Council (UK MRC) protocols ALL97, ALL97/99 and ALL2003 (2005)

Vora,
A.J.,
Richards,
S.,
Hancock,
J.,
...

Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response (2005)

Westerberg,
L.,
Larsson,
M.,
Hardy,
S.J.,
...

The Wiskott-Aldrich syndrome protein (WASp) is mutated in the severe immunodeficiency disease Wiskott-Aldrich syndrome (WAS). The function of B cells and the physiologic alterations in WAS remain...

Failure of SCID-X1 gene therapy in older patients (2005)

Thrasher,
A.J.,
Hacein-Bey-Abina,
S.,
Gaspar,
H.B.,
...

Gene therapy has been shown to be a highly effective treatment for infants with typical X-linked severe combined immunodeficiency (SCID-X1, gammac-deficiency). For patients in whom previous...

Gene Therapy - Great Expectations? (2005)

Thrasher,
A.J.

Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice (2005)

Themis,
M.,
Waddington,
S.N.,
Schmidt,
M.,
...

Gene therapy by use of integrating vectors carrying therapeutic transgene sequences offers the potential for a permanent cure of genetic diseases by stable vector insertion into the patients'...

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates (2005)

Ross,
A.J.,
May-Simera,
H.,
Eichers,
E.R.,
...

The evolutionarily conserved planar cell polarity (PCP) pathway (or noncanonical Wnt pathway) drives several important cellular processes, including epithelial cell polarization, cell migration and...

Handwashing in the intensive care unit: a big measure with modest effects (2005)

Silvestri,
L.,
Petros,
A.J.,
Sarginson,
R.E.,
...

Handwashing is widely accepted as the cornerstone of infection control in the intensive care unit. Nosocomial infections are frequently viewed as an indicator of poor compliance of handwashing. The...

Iron and vitamin A deficiency in long-term African refugees (2005)

Seal,
A.J.,
Creeke,
P.I.,
Mirghani,
Z.,
...

Five cross-sectional surveys were conducted in African refugee camps to assess the level of iron deficiency anemia and vitamin A deficiency in populations dependent on long-term international food...

Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood (2005)

Shaheen,
S.O.,
Newson,
R.B.,
Henderson,
A.J.,
...

Background We recently found that paracetamol (acetaminophen) use in late pregnancy was associated with an increased risk of early wheezing in the offspring. Objective To see whether use of...

Amniotic fluid brain-specific proteins are biomarkers for spinal cord injury in experimental myelomeningocele (2005)

Petzold,
A.,
Stiefel,
D.,
Copp,
A.J.

Myelomeningocele (MMC), the most severe form of spina bifida (SB), causes neurological deficit. Injury to the spinal cord is thought to begin in utero. We investigated whether brain-specific proteins...

Elevated levels of asymmetric di-methylarginine in neonates with congenital diaphragmatic hernia (2005)

Pierce,
C.M.,
Krywawych,
S.,
Petros,
A.J.

No evidence for severe retinopathy of prematurity following sildenafil (2005)

Pierce,
C.M.,
Petros,
A.J.,
Fielder,
A.R.

Update on treatment of human SCID-X1 by somatic gene therapy using a pseudotyped gammaretroviral vector (2005)

Parsley,
K.L.,
Gaspar,
H.B.,
Howe,
S.,
...

Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract (2005)

Phillips,
H.M.,
Murdoch,
J.N.,
Chaudhry,
B.,
...

Loop-tail (Lp) mice develop double outlet right ventricle and aortic arch defects, and the defects are caused by mutations in the Vangl2 gene. Vangl2 mRNA is found in the outflow tract myocardium,...

Analysis of KIT, SCF, and initial screening of SLUG in patients with piebaldism (2005)

Murakami,
T.,
Hosomi,
N.,
Oiso,
N.,
...

Antibasal ganglia antibodies and PANDAS (2005)

Martino,
D.,
Church,
A.J.,
Dale,
R.C.,
...

Lentiviral vectors transcriptionally targeted to hematopoietic cells by WAS gene proximal promoter sequences restore Wiskott-Aldrich Syndrome defects (2005)

Martin,
F.,
Toscano,
M.G.,
Blundell,
M.,
...

Lentiviral vectors transcriptionally targeted to hematopoietic cells by WASP gene proximal promoter sequences (2005)

Martin,
F.,
Toscano,
M.G.,
Blundell,
M.,
...

The development of vectors that express a therapeutic transgene efficiently and specifically in hematopoietic cells (HCs) is an important goal for gene therapy of hematological disorders. In order to...

Soluble adhesion molecules in acute disseminated encephalomyelitis (2005)

Martino,
D.,
Branson,
J.A.,
Church,
A.J.,
...

Soluble adhesion molecules are overexpressed in neuroinflammatory disorders. Their synthesis parallels that of their membrane-bound counterparts, which modulate lymphocyte transmigration through the...

Tracing Sydenham's chorea: historical documents from a British paediatric hospital (2005)

Martino,
D.,
Tanner,
A.,
Defazio,
G.,
...

Sydenham's chorea (SC) became a well defined nosological entity only during the second half of the nineteenth century. Such progress was promoted by the availability of large clinical series provided...

Challenges in the provision of ICU services to HIV infected children in resource poor settings: a South African case study (2005)

Jeena,
P.M.,
McNally,
L.M.,
Stobie,
M.,
...

The HIV/AIDS epidemic has placed increasing demands on limited paediatric intensive care services in developing countries. The decision to admit HIV infected children with Pneumocystis carinii...

In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A (2005)

Ivanova,
A.,
Signore,
M.,
Caro,
N.,
...

We generated a ROSA26-eGFP-DTA mouse line by introducing an eGFP-DTA (enhanced green fluorescent protein - diphtheria toxin fragment A) cassette into the ROSA26 locus by homologous recombination in...

Safety and Immunogenicity of an HIV-1 Recombinant Canarypox Vaccine in Newborns and Infants of HIV-1-Infected Women (2005)

Johnson,
D.C.,
McFarland,
E.J.,
Muresan,
P.,
...

Pediatric AIDS Clinical Trials Group protocol 326 is a study of 2 formulations of recombinant canarypox ALVAC vaccine (vCP205) against human immunodeficiency virus type 1 (HIV-1). HIV-1-exposed...

Mouse models of neural tube defects: Investigating preventive mechanisms (2005)

Greene,
N.D.E.,
Copp,
A.J.

Neural tube defects (NTD), including anencephaly and spina bifida, area group of severe congenital abnormalities in which the future brain and/or spinal cord fail to close. In mice, NTD may result...

Gene therapy for severe combined immunodeficiencies (2005)

Gaspar,
H.B.,
Thrasher,
A.J.

Severe combined immune deficiencies (SCIDs) are a group of monogenic diseases resulting in profound disturbances of lymphocyte development and function. Affected individuals are prone to...

Somatic Gene Therapy for ADA-SCID following cessation of PEG-ADA and use of a mild conditioning regime (2005)

Gaspar,
H.B.,
Bjorkegren,
E.,
Parsley,
K.,
...

Somatic gene therapy for ADA-SCID following cessation of PEG-ADA and use of a mild conditioning regime (2005)

Gaspar,
H.B.,
Bjorkegren,
E.,
Parsley,
K.,
...

Zic4, a zinc-finger transcription factor, is expressed in the developing mouse nervous system (2005)

Gaston-Massuet,
C.,
Henderson,
D.J.,
Greene,
N.D.,
...

Zic genes comprise a family of transcription factors, characterized by the presence of a zinc-finger domain containing two cysteines and two histidines (C2-H2). Whereas the embryonic expression...

Acute lymphoblastic leukaemia has a poor outcome in children with Down syndrome due to infective death in remission - (Results of UK MRC ALL 97 trial) (2005)

De La Fuente,
J.,
Richards,
S.,
Webb,
D.K.,
...

Analysis of the planar cell polarity gene VANGL2 and its co- expressed paralogue VANGL1 in neural tube defect patients (2005)

Doudney,
K.,
Moore,
G.E.,
Stanier,
P.,
...

Analysis of the planar cell polarity gene Vangl2 and its, co-expressed paralog Vangl1 in neural tube defect patients (vol 136A, pg 90, 2005) (2005)

Doudney,
K.,
Moore,
G.E.,
Stanier,
P.,
...

Determination of coenzyme q10 status in blood mononuclear cells, skeletal muscle, and plasma by HPLC with di-propoxy-coenzyme q10 as an internal standard (2005)

Duncan,
A.J.,
Heales,
S.J.R.,
Mills,
K.,
...

Exon array CGH: Detection of copy-number changes at the resolution of individual exons in the human genome (2005)

Dhami,
P.,
Coffey,
A.J.,
Abbs,
S.,
...

The development of high-throughput screening methods such as array-based comparative genome hybridization (array CGH) allows screening of the human genome for copy-number changes. Current array CGH...

Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein (2005)

De Noronha,
S.,
Hardy,
S.,
Sinclair,
J.,
...

Regulated migration and spatial localization of dendritic cells (DCs) are critical events during the initiation of physiologic immune responses and maintenance of tolerance. Here we have used cells...

Incidence of anti-brain antibodies in children with obsessive-compulsive disorder (2005)

Dale,
R.C.,
Heyman,
I.,
Giovannoni,
G.,
...

Background Obsessions and compulsions may occur in the post-streptococcal disorders Sydenham's chorea and paediatric autoimmune neuropsychiatric disorders associated with streptococcus (PANDAS).The...

Linkage disequilibrium mapping in the Newfoundland population: a re-evaluation of the refinement of the Bardet-Biedl syndrome 1 critical interval (2005)

Fan,
Y.L.,
Green,
J.S.,
Ross,
A.J.,
...

Genetically isolated populations, such as Newfoundland, have contributed greatly to the identification of disease-causing genes. A linkage disequilibrium (LD) study involving six Newfoundland...

A familial syndrome of unilateral polymicrogyria affects the right hemisphere (2005)

Chang,
B.S.,
Apse,
K.A.,
Caraballo,
R.,
...

Developmental impairments following severe falciparum malaria in children (2005)

Carter,
J.A.,
Ross,
A.J.,
Neville,
B.G.,
...

OBJECTIVE: Neurological deficits are reported in children after cerebral malaria (CM) but little is known about the prevalence and characteristics of persisting neurocognitive consequences. The...

Lack of serum oligoclonal antibody responses to Chlamydophila pneumoniae in multiple sclerosis (2005)

Chapman,
M.D.,
Hartley,
J.C.,
Furrows,
S.J.,
...

Chlamydophila pneumoniae has been proposed as an aetiological agent in MS via a mechanism involving molecular mimicry. We undertook to investigate whether the presence of CSF oligoclonal IgG OCB or...

Quantitation of the niacin metabolites 1-methylnicotinamide and l-methyl-2-pyridone-5-carboxamide in random spot urine samples, by ion-pairing reverse-phase HPLC with UV detection, and the implications for the use of spot urine samples in the assessment o (2005)

Creeke,
P.I.,
Seal,
A.J.

A simple ion-pairing reverse-phase HPLC method, with UV diode array detection, was developed and validated for quantitation of the urinary niacin metabolites 1-methylnicotinamide and...

Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage (2005)

Broaddus,
V.C.,
Dansen,
T.B.,
Abayasiriwardana,
K.S.,
...

The death ligand, TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), has shown great promise for inducing apoptosis selectively in tumors. Although many tumor cells are resistant to...

Immunology and mathematics: crossing the divide (2005)

Callard,
R.E.,
Yates,
A.J.

'It's high time molecular biology became quantitative, it cries out to a physicist ... for modeling. Modeling isn't a crutch, it's the opposite; it's a way of suggesting experiments to do, to fill...

Inhibition of cortisol production with metyrapone prevents mental stress-induced endothelial dysfunction and baroreflex impairment (2005)

Broadley,
A.J.,
Korszun,
A.,
Abdelaal,
E.,
...

OBJECTIVES: This study was designed to investigate the role of cortisol in stress-induced endothelial dysfunction and impaired baroreflex sensitivity (BRS) by blocking cortisol production with...

Lentiviral gene therapy for Wiskotot Aldrich Syndrome (2005)

Blundell,
M.P.,
Charrier,
S.,
Kinnon,
C.,
...

Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis (2005)

Broderick,
C.A.,
Smith,
A.J.,
Balaggan,
K.S.,
...

Autoimmune posterior uveitis is a chronic, potentially blinding inflammatory disease of the eye. It is commonly treated with immunosuppressive drugs that have adverse long-term effects. Advances in...

Migration of neural crest-derived enteric nervous system precursor cells to and within the gastrointestinal tract (2005)

Burns,
A.J.

The enteric nervous system, the intrinsic innervation of the gastrointestinal tract, consists of large numbers of phenotypically diverse neurons and glial cells, arranged in complex interconnecting...

Neural crest cell origin for intrinsic ganglia of the developing chicken lung (2005)

Burns,
A.J.,
Delalande,
J.M.

The development of intrinsic ganglia, comprised of neurons and glia cells that innervate airway smooth muscle, is a recognized component of the growing lung. However, the embryological origin of...

To be announced (2005)

Brooke,
N.J.,
Antonious,
M.,
Thrasher,
A.J.

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival (2005)

Alvi,
A.J.,
Austen,
B.,
Weston,
V.J.,
...

B-cell chronic lymphocytic leukemia (B-CLL) is a clinically variable disease where mutations in DNA damage response genes ATM or TP53 affect the response to standard therapeutic agents. The in vitro...

Deficient knowledge of genetics relevant for daily practice among medical students nearing graduation (2005)

Baars,
M.J.,
Scherpbier,
A.J.,
Schuwirth,
L.W.,
...

PURPOSE: The objective of this study was to investigate whether the knowledge of genetics relevant for daily practice among medical students nearing graduation in the Netherlands was sufficient to...

Investigating novel retroviral vectors for the treatment of SCID-X1 (2005)

Bailey,
S.I.,
Howe,
S.,
Schambach,
A.,
...

RIC-3 enhances functional expression of multiple nicotinic acetylcholine receptor subtypes in mammalian cells (2005)

Lansdell,
S.J.,
Gee,
V.J.,
Harkness,
P.C.,
...

The association between polycystic ovaries and endometrial cancer (2005)

Pillay,
O.C.,
Wong Te Fong,
L.F.,
Crow,
J.C.,
...

Endometrial gene expression in women with polycystic ovary syndrome. (2005)

Pillay,
O.,
Leonard,
A.J.,
Catalano,
R.,
...

Fundamental subchondral bone changes in spontaneous knee osteoarthritis. (2005)

Anderson-MacKenzie,
J.M.,
Quasnichka,
H.L.,
Starr,
R.L.,
...

Library of Geometric Influences for SIF Weight Functions (2005)

Brennan,
F.P.,
Teh,
L.S.,
Love,
A.J.

Can the frontal assessment battery (FAB) differentiate bradykinetic rigid syndromes? Relation of the FAB to formal neuropsychological testing (2005)

Paviour,
D.C.,
Winterburn,
D.,
Simmonds,
S.,
...

Changes in the circumstances of young mothers in Britain: 1990 to 2000 (2005)

Nanchahal,
K.,
Wellings,
K.,
Barrett,
G.,
...

Factors influencing susceptibility to compulsive dopaminergic drug use in Parkinson disease. (2005)

Evans,
A.H.,
Lawrence,
A.D.,
Potts,
J.,
...

Genotypic variation in Pneumocstis Jirovecii isolates in Britain. (2005)

Miller,
R.F.,
Lindley,
A.R.,
Copas,
A.J.,
...

Investigating the relationship between HIV testing and risk behaviour in Britain: National Survey of Sexual Attitudes and Lifestyles 2000 (2005)

McGarrigle,
C.A.,
Mercer,
C.H.,
Fenton,
K.A.,
...

Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration (2005)

Pittman,
A.M.,
Myers,
A.J.,
Abou-Sleiman,
P.,
...

Local anaesthetic failure in joint hypermobility syndrome (2005)

Hakim,
A.J.,
Grahame,
R.,
Norris,
P.,
...

Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data (2005)

Khan,
N.L.,
Jain,
S.,
Lynch,
J.M.,
...

Parkin disease in a Brazilian kindred: Manifesting heterozygotes and clinical follow-up over 10 years (2005)

Khan,
N.L.,
Horta,
W.,
Eunson,
L.,
...

Quantitative MRI measurement of superior cerebellar peduncle in progressive supranuclear palsy. (2005)

Paviour,
D.C.,
Price,
S.L.,
Stevens,
J.M.,
...

Assay and functional analysis of the ARL3 effector RP2 involved in X-linked retinitis pigmentosa (2005)

Evans,
R.J.,
Chapple,
J.P.,
Grayson,
C.,
...

Mutations in RP2 cause X-linked retinitis pigmentosa and also macular and peripapillary atrophy. RP2 is a functional homologue of the tubulin folding cofactor, cofactor C, as it can replace the beta...

Focus on molecules: nyctalopin (2005)

Poopalasundaram,
S.,
Erskine,
L.,
Cheetham,
M.E.,
...

Gene replacement therapy rescues photoreceptor degeneration in a murine model of Leber congenital amaurosis lacking RPGRIP (2005)

Pawlyk,
B.S.,
Smith,
A.J.,
Buch,
P.K.,
...

PURPOSE: Retinitis pigmentosa GTPase regulator (RPGR) is a photoreceptor protein anchored in the connecting cilia by an RPGR-interacting protein (RPGRIP). Loss of RPGRIP causes Leber congenital...

Identification of novel RPGR ORF15 mutations in X-linked progressive cone-rod dystrophy (XLCORD) families (2005)

Ebenezer,
N.D.,
Michaelides,
M.,
Jenkins,
S.A.,
...

PURPOSE: To test the incidence of mutations in RPGR ORF15 in six families with X-linked progressive retinal degeneration (cone-rod dystrophy [XLCORD], macular or cone dystrophy) and to undertake a...

Inherited ACTH insensitivity illuminates the mechanisms of ACTH action (2005)

Clark,
A.J.,
Metherell,
L.A.,
Cheetham,
M.E.,
...

Adrenocorticotrophin (ACTH) insensitivity is a potentially lethal inherited disorder of ACTH signalling in the adrenal. Inactivating mutations of the ACTH receptor account for approximately 25% of...

Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis (2005)

Broderick,
C.A.,
Smith,
A.J.,
Balaggan,
K.S.,
...

Autoimmune posterior uveitis is a chronic, potentially blinding inflammatory disease of the eye. It is commonly treated with immunosuppressive drugs that have adverse long-term effects. Advances in...

Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy (2005)

Tschernutter,
M.,
Schlichtenbrede,
F.C.,
Howe,
S.,
...

The Royal College of Surgeons (RCS) rat is a well-characterized model of autosomal recessive retinitis pigmentosa (RP) due to a defect in the retinal pigment epithelium (RPE). It is homozygous for a...

Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2 (2005)

Metherell,
L.A.,
Chapple,
J.P.,
Cooray,
S.,
...

Familial glucocorticoid deficiency (FGD), or hereditary unresponsiveness to adrenocorticotropin (ACTH; OMIM 202200), is an autosomal recessive disorder resulting from resistance to the action of ACTH...

Novel CHST6 nonsense and missense mutations responsible for macular corneal dystrophy (2005)

El Ashry,
M.F.,
Abd El-Aziz,
M.M.,
Shalaby,
O.,
...

PURPOSE: To identify the underlying mutations in two unrelated British families with macular corneal dystrophy (MCD) by screening the carbohydrate sulfotransferase (CHST6) gene. DESIGN: Case reports...

Differentiation of an auditory neuronal cell line suitable for cell transplantation (2005)

Nicholl,
A.J.,
Kneebone,
A.,
Davies,
D.,
...

The auditory neuroblast cell line US/VOT-N33 (N33), which is conditionally immortal, was studied as an in vitro model for the differentiation of spiral ganglion neurons (SGNs) and as a candidate for...

Clinical and molecular characterization of a family with autosomal recessive cornea plana (2005)

Ebenezer,
N.D.,
Patel,
C.B.,
Hariprasad,
S.M.,
...

BACKGROUND: Autosomal recessive cornea plana is characterized by a flattened corneal surface associated with hyperopia and various anterior segment abnormalities. Mutations have been detected in the...

Posterior polymorphous corneal dystrophy in Czech families maps to chromosome 20 and excludes the VSX1 gene (2005)

Gwilliam,
R.,
Liskova,
P.,
Filipec,
M.,
...

PURPOSE: Posterior polymorphous corneal dystrophy (PPCD) is an autosomal dominant disorder, affecting both the corneal endothelium and Descemet's membrane. In the Czech Republic, PPCD is one of the...

Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for beta1 but not for palmitoylated beta2, implicating an additional binding site in the regulation of channel voltage-dependent properties. (2005)

Leroy,
J.,
Richards,
M.W.,
Butcher,
A.J.,
...

A Functional Role for Small-Conductance Calcium-Activated Potassium Channels in Sensory Pathways Including Nociceptive Processes. (2005)

Bahia,
P.K.,
Suzuki,
R.,
Benton,
D.C.H.,
...

Amplitude of ENSO cycles in the Santa Barbara Basin, off California, during the past 15 000 years. (2005)

Nederbragt,
A.J.,
Thurow,
J.W.

Glacial and Interglacial Climate Cycles from a Varved Record (Core MD02-2515) in the Guaymas Basin (Gulf of California). (2005)

Thurow,
J.W.,
Brumsack,
H.,
Cheshire,
H.,
...

Late Quaternary climate change record from two long sediment cores from Guaymas Basin, Gulf of California. (2005)

Cheshire,
H.,
Thurow,
J.W.,
Nederbragt,
A.J.

Orbital-scale Record of the Late Cenomanian-Turonian Oceanic Anoxic Event (OAE-2) in the Tarfaya Basin (Morocco). (2005)

Kuhnt,
W.,
Luderer,
F.,
Nederbragt,
A.J.,
...

Sediment Composition and Cyclicity in the Mid-Cretaceous at Demerara Rise (ODP Leg 207): Productivity or Anoxia Driven? (2005)

Nederbragt,
A.J.,
Thurow,
J.W.,
Pearce,
R.

Triphenylphosphine-substituted selenido and sulfido clusters of osmium derived from Ph₃P=Se or Ph₃P=S (2005)

Akter,
H.,
Deeming,
A.J.,
Hossain,
G.M.G.,
...

Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up (2005)

Zajicek,
J.P.,
Sanders,
H.P.,
Wright,
D.E.,
...

The distribution of magnetic resonance imaging response to interferonbeta-1b in multiple sclerosis (2005)

Sormani,
M.P.,
Bruzzi,
P.,
Beckmann,
K.,
...

Atypical unclassifiable parkinsonism on Guadeloupe: an environmental toxic hypothesis (2005)

Caparros-Lefebvre,
D.,
Lees,
A.J.

Clinical grand round: a rapidly progressive pyramidal and extrapyramidal syndrome with a supranuclear gaze palsy (2005)

Morris,
H.R.,
Bronstein,
A.M.,
Shaw,
C.E.,
...

Defining the ends of Parkin exon 4 deletions in two different families with Parkinson's disease (2005)

Clarimon,
J.,
Johnson,
J.,
Dogu,
O.,
...

Development, characterisation and epitope mapping of novel monoclonal antibodies for DJ-1 (PARK7) protein (2005)

Bandopadhyay,
R.,
Miller,
D.W.,
Kingsbury,
A.E.,
...

Kufor Rakeb disease: autosomal recessive, levodopa-responsive parkinsonism with pyramidal degeneration, supranuclear gaze palsy, and dementia (2005)

Williams,
D.R.,
Hadeed,
A.,
Najim Al-Din,
A.S.,
...

Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy (2005)

Lewerenz,
J.,
Zurowski,
B.,
Jenicke,
L.,
...

Parkinson's disease: a broken nosology (2005)

Hardy,
J.,
Lees,
A.J.

Reply: Lack of association between progressive supranuclear palsy and arterial hypertension: a clinicopathological study (2005)

Colosimo,
C.,
Osaki,
Y.,
Vanacore,
N.,
...

The fragile X tremor ataxia syndrome in the differential diagnosis of multiple system atrophy: data from the EMSA Study Group (2005)

Kamm,
C.,
Healy,
D.G.,
Quinn,
N.P.,
...

Risk of second malignancy after non-Hodgkin's lymphoma: A British cohort study (2005)

Mudie,
N.Y.,
Swerdlow,
A.J.,
Higgins,
C.D.,
...

An over-optimistic pioneer fringe? Environmental perspectives on medieval settlement abandonment in Þórsmörk, south Iceland (2005)

Dugmore,
A.J.,
Mairs,
K-A.,
Church,
M.J.,
...

Degrees of success: evaluating the environmental impacts of successful long term settlement in south Iceland (2005)

Mairs,
K-A.,
Dugmore,
A.J.,
Church,
M.J.,
...

Reply to comment on "Compositional and structural control of fission-track annealing in apatite" by J. Barbarand, A. Carter, I. Wood and A.J. Hurford, Chemical Geology 198, 107-137, 2003 (2005)

Hurford,
A.J.,
Barbarand,
J.,
Carter,
A.

Evening transition observations in Phoenix, Arizona, USA. (2005)

Brazel,
A.J.,
Fernando,
H.J.S.,
Hunt,
J.C.R.,
...

3,4-Dichloro-1-nitrobenzene-aniline (2/1) (2005)

Barnett,
S.A.,
Johnston,
A.,
Florence,
A.J.,
...

Two 8-month regimens of chemotherapy for treatment of newly diagnosed pulmonary tuberculosis: international multicentre randomised trial (2004)

Jindani,
A.,
Nunn,
A.J.,
Enarson,
D.A.

Excited-state dynamics of fac-[ReI(L)(CO)3(phen)]+ and fac-[ReI(L)(CO)3(5-NO2-phen)]+ (L = imidazole, 4-ethylpyridine; phen = 1,10-phenanthroline) complexes. (2004)

Busby,
M.,
Gabrielsson,
A.,
Matousek,
P.,
...

Maturation of DC is associated with changes in motile characteristics and adherence (2004)

Burns,
S.,
Hardy,
S.J.,
Buddle,
J.,
...

Mechanisms of WASp-mediated hematologic and immunologic disease (2004)

Burns,
S.,
Cory,
G.O.,
Vainchenker,
W.,
...

The Wiskott-Aldrich syndrome protein (WASp) is a key regulator of actin polymerization in hematopoietic cells. The dynamic nature of cytoskeletal changes during a variety of cellular processes...

Rehabilitation of the cancer patient: Experience in a neurological unit (2004)

Garrard,
P.,
Farnham,
C.,
Thompson,
A.J.,
...

Increasing prevalence of male homosexual partnerships and practices in Britain 1990-2000: Evidence from national probability surveys. (2004)

Mercer,
C.H.,
Fenton,
K.A.,
Copas,
A.J.,
...

Studies of the collagen-like peptide (Pro-Pro-Gly)(10) confirm that the shape and position of the type I collagen denaturation endotherm is governed by the rate of helix unfolding. (2004)

Miles,
C.A.,
Bailey,
A.J.

Radiolabelling of glycosylated MFE-23 :: CPG2 fusion protein (MFECP1) with Tc-99m for quantitation of tumour antibody-enzyme localisation in antibody-directed enzyme pro-drug therapy (ADEPT) (2004)

Francis,
R.J.,
Mather,
S.J.,
Chester,
K.,
...

MFECP1 is a glycosylated recombinant fusion protein composed of MFE-23, a high-affinity anti-carcinoembryonic antigen (CEA) single chain Fv (scFv), fused to the enzyme carboxypeptidase G2 (CPG2), and...

First heterosexual partnerships: Age difference and their significance. Empirical evidence from the National Survey of Sexual Attitudes and Lifestyles 2000 (`Natsal 2000`) (2004)

Mercer,
C.H.,
Copas,
A.J.,
Macdowell,
W.,
...

RhoA activation by hypoxia in pulmonary arterial smooth muscle cells is age and site specific (2004)

Bailly,
K.,
Ridley,
A.J.,
Hall,
S.M.,
...

Hypoxia induces vasoconstriction of pulmonary arteries through contraction of smooth muscle cells (SMCs). The GTPase RhoA regulates smooth muscle contractility and actin cytoskeletal remodeling...

Enteric neural crest-derived cells and neural stem cells: biology and therapeutic potential (2004)

Burns,
A.J.,
Pasricha,
P.J.,
Young,
H.M.

The enteric nervous system arises from two regions of the neural crest; the vagal neural crest which gives rise to the vast majority of enteric neurones throughout the gastrointestinal tract, and the...

Hepatic nervous system development (2004)

Delalande,
J.M.,
Milla,
P.J.,
Burns,
A.J.

During embryonic development, the liver emerges from the foregut as a thickening of the ventral endodermal epithelium. The embryonic liver then develops into a bud of cells that proliferates and...

Impaired bone marrow homing of cytokine-activated CD34+ cells in the NOD/SCID model (2004)

Ahmed,
F.,
Ings,
S.J.,
Pizzey,
A.R.,
...

The reduced engraftment potential of hematopoietic stem/progenitor cells (HSPCs) after exposure to cytokines may be related to the impaired homing ability of actively cycling cells. We tested this...

Clinical audit in Nuclear Medicine (2004)

Peters,
A.M.,
Bomanji,
J.B.,
Costa,
D.C.,
...

A randomised placebo-controlled trial of cotrimoxazole as prophylaxis against opportunistic ifnections in HIV-infected zambian children: the CHAP trial (2004)

Chintu,
C.,
Bhat,
G.J.,
Walker,
A.S.,
...

Identification of a new cross-link and unique histidine adduct from bovine serum albumin incubated with malondialdehyde. (2004)

Slatter,
D.A.,
Avery,
N.C.,
Bailey,
A.J.

Anti-basal ganglia antibodies in patients with atypical dystonia and tics - A prospective study (2004)

Edwards,
M.J.,
Trikouli,
E.,
Martino,
D.,
...

Clinical-anatomical correlation in a selective phonemic speech production impairment. (2004)

Larner,
A.J.,
Robinson,
G.,
Kartsounis,
L.D.,
...

Clinicopathological investigation of vascular parkinsonism, including clinical criteria for diagnosis (2004)

Zijlmans,
J.C.,
Daniel,
S.E.,
Hughes,
A.J.,
...

Effect of Mycobacterium vaccae (SRL172) immunotherapy on radiographic healing in tuberculosis (2004)

Johnson,
J.L.,
Nunn,
A.J.,
Fourie,
P.B.,
...

Pathological substrate for regional distribution of increased atrophy rates in progressive supranuclear palsy (2004)

Paviour,
D.C.,
Schott,
J.M.,
Stevens,
J.M.,
...

Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism. (2004)

Scherfler,
C.,
Khan,
N.L.,
Pavese,
N.,
...

The influence of time after stroke on brain activations during a motor task. (2004)

Ward,
N.,
Brown,
M.M.,
Thompson,
A.J.,
...

2004: 8.097

The sensitivity of estimates of the change in population behaviour to realistic changes in bias in repeated surveys (2004)

Copas,
A.J.,
Farewell,
V.T.,
Mercer,
C.M.,
...

Women and health care professionals' preferences for Down's Syndrome screening tests: a conjoint analysis study. (2004)

Bishop,
A.J.,
Marteau,
T.,
Armstrong,
D.,
...

Successful gene therapy of SCID-X1 using a pseudotyped gammaretroviral vector (2004)

Gaspar,
H.B.,
Parsley,
K.,
Howe,
S.,
...

Dominant-negative calcium channel suppression by truncated constructs involves a kinase implicated in the unfolded protein response (2004)

Page,
K.M.,
Heblich,
F.,
Davies,
A.,
...

Ca2+ channel beta-subunits: structural insights AID our understanding (2004)

Richards,
M.W.,
Butcher,
A.J.,
Dolphin,
A.C.

A frequency domain measurement diagnostic technique for plasma-tools (2004)

Law,
V.J.,
Kenyon,
A.J.,
Thornhill,
N.F.,
...

The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. (2004)

Bandopadhyay,
R.,
Kingsbury,
A.E.,
Cookson,
M.R.,
...

2004: 8.201

Beam tests of ATLAS SCT silicon strip detector modules (2004)

Barr,
A.J.,
Anderson,
B.E.,
Butterworth,
J.M.,
...

The design and technology of the silicon strip detector modules for the Semiconductor Tracker (SCT) of the ATLAS experiment have been finalised in the last several years. Integral to this process has...

Clinico-pathological findings in haemolytic uraemic syndrome not associated with diarrhoea (2004)

Taylor,
C.M.,
Chua,
C.,
Howie,
A.J.,
...

An ELISA for glial fibrillary acidic protein (2004)

Petzold,
A.,
Keir,
G.,
Green,
A.J.,
...

Serum S100B in primary progressive multiple sclerosis patients treated with interferon-beta-1a (2004)

Lim,
E.T.,
Petzold,
A.,
Leary,
S.M.,
...

An early Middle Pleistocene mammalian fauna from Pakefield-Kessingland, Suffolk. (2004)

Stuart,
A.J.,
PARFITT,
S.A.,
Breda,
M.

CD56 bright natural killer cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation (2004)

Dalbeth,
N.,
Gundle,
R.,
Davies,
R.J.O,
...

Production and regulation of lignin degrading enzymes from Lentinus squarrosulus (mont.) Singer and Psathyrella atroumbonata Pegler (2003)

WUYEP. P. A KHAN,
A. U,
NOK,
A. J.

The influence of metal ions on the production and regulation of ligninase and mycelia extension of two type Basidiomycetes (Lentinus squarrosulus and Psathyrella atroumbonata ) cultivated on...

PtII diimine chromophores with perfluorinated thiolate ligands: nature and dynamics of the charge-transfer-to-diimine lowest excited state. (2003)

Weinstein,
J.A.,
Blake,
A.J.,
Davies,
E.S.,
...

Cerebral amyloid angiopathy and motor neurone disease presenting with a progressive supranuclear palsy-like syndrome (2003)

Weeks,
R.A.,
Scaravilli,
F.,
Lees,
A.J.,
...

Optically-driven silicon-based quantum gates with potential for high temperature operation (2003)

Stoneham,
A.M.,
Fisher,
A.J.,
Greenland,
P.T.

Effect of social exclusion on the risk of teenage pregnancy: development of hypotheses using baseline data from a randomised trial of sex education (2003)

Bonell,
C.P.,
Strange,
V.J.,
Stephenson,
J.M.,
...

Properties of collagen in OIM mouse tissues. (2003)

Sims,
T.J.,
Miles,
C.A.,
Bailey,
A.J.,
...

Asymmetry in the triple helix of collagen-like heterotrimers confirms that external bonds stabilize collagen structure. (2003)

Slatter,
D.A.,
Miles,
C.A.,
Bailey,
A.J.

Facial expression recognition across the adult lifespan (2003)

Calder,
A.J.,
Keane,
J.,
Manly,
T.,
...

Improved anti-tumor immunity in murine neuroblastoma using a combination of IL-2 and IL-12 (2003)

Siapati,
K.E.,
Barker,
S.,
Kinnon,
C.,
...

Neuroblastoma immunotherapy using cytokine-modified tumour cells has been tested in clinical trials. However, because of the complex nature of antitumour immune responses, a number of therapies may...

Chemical stabilisation of collagen as a biomimetic. (2003)

Paul,
R.G.,
Bailey,
A.J.

Lysyl oxidase is required for vascular and diaphragmatic development in mice. (2003)

Hornstra,
I.K.,
Birge,
S.,
Starcher,
B.,
...

Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties. (2003)

Bellingham,
C.M.,
Lillie,
M.A.,
Gosline,
J.M.,
...

Phenotype and genotype of interfollicular large B cells, a subpopulation of lymphocytes often with dendritic morphology (2003)

Marafioti,
T.,
Jones,
M.,
Facchetti,
F.,
...

A general purpose implementation of the QM/MM approach and its application to problems in catalysis (2003)

Sherwood,
P.,
De Vries,
A.H.,
Guest,
M.F.,
...

A novel approach to the recognition of protein architecture from sequence using Fourier analysis and neural networks (2003)

Shepherd,
A.J.,
Gorse,
D.,
Thornton,
J.M.

Bactericidal activity of antituberculosis drugs (2003)

Doré,
C.J.,
Nunn,
A.J.,
Gillespie,
S.H.,
...

BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro (2003)

Kalsi,
J.S.,
Rees,
R.W.,
Hobbs,
A.J.,
...

Drug-resistant HIV-1 in the semen of men receiving antiretroviral therapy with acute sexually transmitted infections (2003)

Taylor,
S.,
Sadiq,
S.T.,
Weller,
I.,
...

Fluoride uptake by glass ionomer cements: a surface analysis approach (2003)

Jones,
F.H.,
Hutton,
B.M.,
Hadley,
P.C.,
...

In vivo killing of Porphyromonas gingivalis by Toluidine Blue-mediated photosensitization in an animal model (2003)

Komerik,
N.,
Nakanishi,
H.,
Macrobert,
A.J.,
...

Making occlusion work: 1. Terminology, occlusal assessment and recording (2003)

McCullock,
A.J.

Making occlusion work: 2. Practical considerations (2003)

McCullock,
A.J.

Measurement and analysis of brain deformation during neurosurgery (2003)

Hartkens,
T.,
Hill,
D.L.,
Castellano-Smith,
A.D.,
...

Recent studies have shown that the surface of the brain is deformed by up to 20 mm after the skull is opened during neurosurgery, which could lead to substantial error in commercial image-guided...

Non-Axisymmetrical (Life-Like) Abdominal Aortic Aneurysm Models: A Do-It-Yourself-Approach (2003)

Chaudhuri,
A.,
Ansdell,
L.E.,
Richards,
R.,
...

Organization on the plasma membrane of the retinitis pigmentosa protein RP2: investigation of association with detergent-resistant membranes and polarized sorting (2003)

Chapple,
J.P.,
Grayson,
C.,
Hardcastle,
A.J.,
...

Mutations in the retinitis pigmentosa protein gene RP2 account for up to 15% of X-linked retinitis pigmentosa. RP2 is a novel protein of unknown function, which is targeted to the plasma membrane by...

Peridontal Tissue Destruction and Remodelling (2003)

Konstantinidis,
A.,
Lamster,
I.,
Lange,
D.E.,
...

Poor sensitivity and consistency of microscopy in the diagnosis of low grade non-gonococcal urethritis (2003)

Smith,
R.,
Copas,
A.J.,
Prince,
M.,
...

Prions and the human transmissible spongiform encephalopathies (2003)

Scully,
C.,
Smith,
A.J.,
Bagg,
J.

Prions and the oral cavity (2003)

Smith,
A.J.,
Bagg,
J.,
Ironside,
J.W.,
...

Stable rAAV-mediated transduction of rod and cone photoreceptors in the canine retina (2003)

Bainbridge,
J.W.,
Mistry,
A.,
Schlichtenbrede,
F.C.,
...

The shape and size of crowding for moving targets (2003)

Bex,
P.J.,
Dakin,
S.C.,
Simmers,
A.J.

Our ability to identify alphanumeric characters can be impaired by the presence of nearby features, especially when the target is presented in the peripheral visual field, a phenomenon is known as...

Viral Hepatitis (2003)

Zuckerman,
J.N.,
Zuckerman,
A.J.

Generation of immunostimulatory dendritic cells from the malignant clone in patients with juvenile myelomonocytic leukemia (2003)

Nabarro,
S.,
Thrasher,
A.J.,
Kempski,
H.,
...

Die Funktionalität des lateral-präfrontalen Cortex für die Verarbeitung von Doppelaufgaben (2003)

Szameitat,
A. J.

Die vorliegende Arbeit hatte einerseits zum Ziel, die Funktionalität des lateral-präfrontalen Cortex (LPFC) für die Doppelaufgaben-Verarbeitung nachzuweisen und andererseits die Charakteristik...

Die Funktionalität des lateral-präfrontalen Cortex für die Verarbeitung von Doppelaufgaben (2003)

Szameitat,
A. J.

Die vorliegende Arbeit hatte einerseits zum Ziel, die Funktionalität des lateral-präfrontalen Cortex (LPFC) für die Doppelaufgaben-Verarbeitung nachzuweisen und andererseits die Charakteristik...

Non-invasive diagnosis of tracheobronchomalacia using a modified ventilation radioisotope lung scan (2003)

Gour,
A.,
Peters,
M.J.,
Gordon,
I.,
...

Harmonic monitoring of the switched silicon etched process (2003)

Thornhill,
N.F.,
Law,
V.J.,
Kenyon,
A.J.,
...

Harmonic monitoring of the switched silicon etch process (2003)

Law,
V.J.,
Thornhill,
N.F.,
Kenyon,
A.J.,
...

Regulation of Expression of Neuronal and Astrocytic Cytoskeletal Proteins in the Fetal Brain by Maternal Thyroid Status (2003)

Pickard,
M.R.,
Sampson,
D.,
Evans,
I.M.,
...

Deficits in a tricarboxylic acid cycle enzyme in brains from patients with Parkinson's disease (2003)

Gibson,
G.E.,
Kingsbury,
A.E.,
Xu,
H.,
...

Genetic interaction of BBS1 mutations with alleles at other BBS loci can result in non-Mendelian Bardet-Biedl syndrome (2003)

Beales,
P.L.,
Badano,
J.L.,
Ross,
A.J.,
...

Cannabinoids inhibit neurodegeneration in models of multiple sclerosis (2003)

Pryce,
G.,
Ahmed,
Z.,
Hankey,
D.J.R.,
...

Baculovirus capsid display: a novel tool for transduction imaging (2003)

Kukkonen,
S.P.,
Airenne,
K.J.,
Marjomaki,
V.,
...

Baculoviruses are enveloped insect viruses that can carry large quantities of foreign DNA in their genome. Baculoviruses have proved to be very promising gene therapy vectors but little is known...

A Decade of Change: Tuberculosis in England and Wales 1988-1998 (2003)

Balasegaram,
S.,
Watson,
J.M.,
Charlett,
A.,
...

The impact of tailings dam spills and clean-up operations on sediment and water quality in river systems: The R¡os Agrio-Guadiamar, Aznalc¢llar, Spain (2003)

Hudson-Edwards,
K.A.,
Macklin,
M.G.,
Jamieson,
H.E.,
...

Introduction, Science and applications of the space environment: new results and interdisciplinary connections (2003)

CULHANE,
J.L.,
Hunt,
J.C.R.,
COATES,
A.J.

Developments in space engineering and space science (2003)

Hunt,
J.C.R.,
COATES,
A.J.

16-18 Oct 2001

The influence of the thermal diffusivity of the lower boundary on eddy motion in convection (2003)

Hunt,
J.C.R.,
Vrieling,
A.J.,
Nieuwstadt,
F.T.M.,
...

Tubular aggregate myopathy with abnormal pupils and skeletal deformities (2002)

Jacques,
T.S.,
Holton,
J.,
Watts,
P.M.,
...

Cognitive dysfunction after isolated brain stem insult. An underdiagnosed cause of long term morbidity (2002)

Garrard,
P.,
Bradshaw,
D.,
Jager,
H.R.,
...

Reading the mind from eye gaze. (2002)

Calder,
A.J.,
Lawrence,
A.D.,
Keane,
J.,
...

Phenotypic expression of osteoblast collagen in osteoarthritic bone: production of type I homotrimer. (2002)

Bailey,
A.J.,
Sims,
T.J.,
Knott,
L.

The role of the alpha2 chain in the stabilization of the collagen type I heterotrimer: a study of the type I homotrimer in oim mouse tissues. (2002)

Miles,
C.A.,
Sims,
T.J.,
Camacho,
N.P.,
...

Phonon spectroscopy of orientated hcp iron (2002)

Giefers,
H.,
Lubbers,
R.,
Rupprecht,
K.,
...

Fetal haemapoietic cells display enhanced migration across endothelium (2002)

Yong,
K.L.,
Fahey,
A.,
Pahal,
G.,
...

Ocular developmental abnormalities and glaucoma associated with interstitial 6p25 duplications and deletions (2002)

Lehmann,
O.J.,
Ebenezer,
N.D.,
Ekong,
R.,
...

PURPOSE: Mutations in the forkhead transcription factor gene FOXC1 on 6p25 cause a range of ocular developmental abnormalities, with associated glaucoma. However, FOXC1 mutations have not been found...

Cross-link profile of bone collagen correlates with structural organization of trabeculae. (2002)

Banse,
X.,
Devogelaer,
J.P.,
Lafosse,
A.,
...

Mechanical properties of adult vertebral cancellous bone: correlation with collagen intermolecular cross-links. (2002)

Banse,
X.,
Sims,
T.J.,
Bailey,
A.J.

Differences in composition of avian bone collagen following genetic selection for resistance to osteoporosis. (2002)

Sparke,
A.J.,
Sims,
T.J.,
Avery,
N.C.,
...

Changes in bone collagen with age and disease. (2002)

Bailey,
A.J.

Antibody and radionuclide characteristics and the enhancement of the effectiveness of radioimmunotherapy by selective dose delivery to radiosensitive areas of tumour (2002)

Flynn,
A.A.,
Pedley,
R.B.,
Green,
A.J.,
...

Purpose: Estimating the absorbed dose to tumour relative to normal tissues has often been used in the assessment of the therapeutic efficacy of radiolabelled antibodies for radioimmuno-therapy....

Effect of porosity reduction by compaction on compressive strength and microstructure of calcium phosphate cement (2002)

Barralet,
J.E.,
Gaunt,
T.,
Wright,
A.J.,
...

Extension, retraction and contraction in the formation of a dendritic cell dendrite: dinstinct roles for Rho GTPases (2002)

Swetman,
C.A.,
Leverrier,
Y.,
Garg,
R.,
...

Influence of maternal hyperthyroidism in the rat on the expression of neuronal and astrocytic cytoskeletal proteins in fetal brain (2002)

Evans,
I.M.,
Pickard,
M.R.,
Sinha,
A.K.,
...

Thickness of articular calcified cartilage in normal and osteoarthritic human femoral heads (2002)

Ferguson,
V.L.,
Partap,
S.,
Bushby,
A.J.,
...

Modulus and mineralization of articular calcified cartilage and subchondral bone in osteoarthritic via nanoindentation and quantitative backscattered electron imaging (2002)

Ferguson,
V.L.,
Bushby,
A.J.,
Boyde,
A.

Mineralization and nano-mechanical properties of human femoral articular calcified cartilage and subchondral bone (2002)

Ferguson,
V.L.,
Bushby,
A.J.,
Boyde,
A.

Changes in the regulation of the actin cytoskeleton and RhoA activity induced by acute hypoxia in pulmonary arterial smooth muscle cells (2002)

Bailly,
K.,
Ridley,
A.J.,
Hall,
S.M.,
...

Pathological, clinical and genetic heterogeneity in progressive supranuclear palsy (2002)

Morris,
H.R.,
Gibb,
G.,
Katzenschlager,
R.,
...

A common mechanism of action for the mood stabilisers lithium, carbamazepine and valproic acid (2002)

Williams,
R.S.,
Cheng,
L.,
Mudge,
A.W.,
...

A common mechanism of action for three mood-stabilizing drugs (2002)

Williams,
R.S.,
Cheng,
L.,
Mudge,
A.W.,
...

Lithium, carbamazepine and valproic acid are effective mood-stabilizing treatments for bipolar affective disorder. The molecular mechanisms underlying the actions of these drugs and the illness...

Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation (2001)

Burns,
S.,
Thrasher,
A.J.,
Blundell,
M.P.,
...

Conditional immortalisation of freshly isolated human mammary fibroblasts and endothelial cells (2001)

O'Hare,
M.,
Bond,
J.,
Clarke,
C.,
...

Reducing sexually transmitted infections among gay men (2001)

Imrie,
J.,
Stephenson,
J.M.,
Cowan,
F.M.,
...

A cognitive behavioural intervention to reduce sexually transmitted infections among gay men: randomised trial (2001)

Imrie,
J.,
Stephenson,
J.M.,
Cowan,
F.M.,
...

Semi quantitative analysis of F18-FDG imaging using a hybrid camera for the assessment of tumour response to therapy (2001)

Green,
A.J.,
Baig,
S.,
Francis,
R.J.,
...

Energy metabolism of infants and children with systemic inflammatory response syndrome and sepsis (2001)

Turi,
R.A.,
Petros,
A.J.,
Eaton,
S.,
...

Gene replacement therapy in the retinal degeneration slow (rds) mouse: the effect on retinal degeneration following partial transduction of the retina (2001)

Sarra,
G.M.,
Stephens,
C.,
De Alwis,
M.,
...

The retinal degeneration slow (rds or Prph2(Rd2/Rd2)) mouse, a model of recessive retinitis pigmentosa, lacks a functional gene encoding peripherin 2. This membrane glycoprotein is required for the...

Optimization of recombinant adeno-associated virus production using an herpes simplex virus amplicon system (2001)

Feudner,
E.,
De Alwis,
M.,
Thrasher,
A.J.,
...

A major limitation of adeno-associated virus (AAV) based vectors for clinical applications to date is the production of high-titer recombinant AAV vector stocks. Despite recent improvements, the...

Morphine induces short-lived changes in G-protein gene expression in rat prefrontal cortex (2001)

Kaewsuk,
S.,
Hutamekalin,
P.,
Ketterman,
A.J.,
...

We have utilized a reverse transcriptase-polymerase chain reaction (RT- PCR) methodology followed by enzymatic restriction analysis to detect changes in G-protein mRNA levels in morphine-treated...

Evaluation of a new technique for monitoring peristaltic frequency, pressure and conduction velocity in the ureter (2001)

Young,
A.J.,
Miller,
R.A.,
Kellett,
M.J.,
...

Anabolic effect of long-term estrogen replacement on bone collagen in elderly postmenopausal women with osteoporosis. (2001)

Khastgir,
G.,
Studd,
J.,
Holland,
N.,
...

Refsum's disease (2001)

Wills,
A.J.,
Manning,
N.J.,
Reilly,
M.M.

RF probe technology for the next generation of technological plasmas (2001)

Law,
V.J.,
Kenyon,
A.J.,
Thornhill,
N.F.,
...

Data-driven recognition memory: A new technique and some data on age differences (2001)

Parkin,
A.J.,
Ward,
J.,
Squires,
E.,
...

A quantitative assessment of protoporphyrin IX metabolism and phototoxicity in human skin following dose-controlled delivery of the prodrugs 5-aminolaevulinic acid and 5-aminolaevulinic acid-n-pentylester (2001)

Gerscher,
S.,
Connelly,
J.P.,
Beijersbergen Van Henegouwen,
G.M.,
...

T3 stimulates alpha-internexin protein, but not mRNA, levels in neurons in culture. Poster presented at 27th Annual Meeting of European Thyroid Association, Warsaw, Poland. 25-29 August 2001 (2001)

Sampson,
D.C.,
Pickard,
M.R.,
Evans,
I.M.,
...

Thyroid hormone regulation of alpha-internexin expression during early neuronal differentiation. Poster presented at the 20th Joint Meeting of the British Endocrine Societies, Belfast, UK. 26-29 March 2001 (2001)

Sampson,
D.C.,
Pickard,
M.R.,
Leonard,
A.J.,
...

Maternal hyperthyroidism disrupts neuronal development in late fetal brain. Poster presented at 192nd Meeting of the Society for Endocrinology, London, UK. 3-4 December 2001 (2001)

Evans,
I.M.,
Pickard,
M.R.,
Sinha,
A.K.,
...

Maternal hypothyroidism and T3 receptor expression in rat placenta. Poster presented at the 27th Annual Meeting of European Thyroid Association, Warsaw, Poland. 25-29 August 2001 (2001)

Leonard,
A.J.,
Evans,
I.M.,
Pickard,
M.R.,
...

Thyroid hormone receptor expression in rat placenta (2001)

Leonard,
A.J.,
Evans,
I.M.,
Pickard,
M.R.,
...

Surveillance neuroimaging in childhood intracranial ependymoma: how effective, how often, and for how long? (2001)

Good,
C.D.,
Wade,
A.M.,
Hayward,
R.D.,
...

Gene polymorphism in Netherton and common atopic disease (2001)

Walley,
A.J.,
Chavanas,
S.,
Moffatt,
M.E.,
...

Enteric nervous system development: analysis of the selective developmental potentialities of vagal and sacral neural crest cells using quail-chick chimeras. (2001)

Burns,
A.J.,
Le Douarin,
N.M.

The majority of the enteric nervous system (ENS) is derived from vagal neural crest cells (NCC). For many years, the contribution from a second region of the neuraxis (the sacral neural crest) to the...

Temporal variation in endotoxin-induced vascular hyporeactivity in a rat mesenteric artery organ culture model (2001)

O'Brien,
A.J.,
Wilson,
A.J.,
Sibbald,
R.,
...

Endotoxin-induced vascular hyporeactivity to phenylephrine (PE) is well described in rodent aorta, but has not been investigated in smaller vessels in vitro. Segments of rat superior mesenteric...

VIDA: a virus database system for the organization of animal virus genome open reading frames (2001)

Alba,
M.M.,
Lee,
D.,
Pearl,
F.M.,
...

VIDA is a new virus database that organizes open reading frames (ORFs) from partial and complete genomic sequences from animal viruses. Currently VIDA includes all sequences from GenBank for...

Conjunctivitis due to Chlamydophilia felis acquired from cat: case report with molecular characterisation of isolates from the patient and his cat (2001)

Hartley,
J.C.,
Stevenson,
S.,
Robinson,
A.J.,
...

Water diffusion is elevated in widespread regions of normal- appearing white matter in multiple sclerosis and correlates with diffusion in focal lesions (2001)

Werring,
D.J.,
Clark,
C.A.,
Droogan,
A.G.,
...

Evidence of association and linkage disequilibrium between a novel polymorphism in the transforming growth factor beta 1 gene and hip bone mineral density: a study of female twins (2001)

Keen,
R.W.,
Snieder,
H.,
Molloy,
H.,
...

OBJECTIVE: Bone mineral density (BMD) in later life is a major determinant of osteoporotic fracture risk and has been shown to be under strong genetic influence. Transforming growth factor beta 1...

Shock strengths in clumps impacted by winds of increasing power (2001)

Lim,
A.J.,
Hartquist,
T.W.,
Williams,
D.A.

Adeno-associated and herpes simplex viruses as vectors for gene transfer to the corneal endothelium (2000)

Hudde,
T.,
Rayner,
S.A.,
De Alwis,
M.,
...

PURPOSE: We examined the efficacy and cytopathogenicity of adeno- associated (AAV) and herpes simplex viruses (HSV) as vectors for gene transfer to corneal endothelial cells (CECs). METHODS:...

Neuroprotective efficacy and therapeutic window of the high-affinity N-methyl-D-aspartate antagonist conantokin-G: in vitro (primary cerebellar neurons) and in vivo (rat model of transient focal brain ischemia) studies. (2000)

Williams,
A.J.,
Dave,
J.R.,
Phillips,
J.B.,
...

Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia. (2000)

Phillips,
J.B.,
Williams,
A.J.,
Adams,
J.,
...

Preoperative diagnosis of ovarian carcinoma with a novel monoclonal antibody (2000)

Lieberman,
G.,
Buscombe,
J.R.,
Hilson,
A.J.,
...

Molecular and cellular mecahnisms in endotoxic shock: are potassium channels a novel therapeutic target (2000)

Wilson,
A.W.,
O'Brien,
A.J.,
Singer,
M.,
...

Remote coupled sensing of plasma harmonics and process end-point detection (2000)

Law,
V.J.,
Kenyon,
A.J.,
Thornhill,
N.,
...

Remote-coupled Sensing of Plasma Harmonics and Process End-point Detection: An Equivalent Linear Electrical Circuit Model (2000)

Law,
V.J.,
Kenyon,
A.J.,
Thornhill,
N.,
...

Maternal hypothyroidism and feto-placental nuclear 3,5,3' triiodothyronine binding (2000)

Leonard,
A.J.,
Evans,
I.M.,
Pickard,
M.R.,
...

22 Nov 2000

Maternal thyroid status regulates the expression of neuronal and astrocytic cytoskeletal proteins in the fetal brain (2000)

Sampson,
D.,
Pickard,
M.,
Sinha,
A.K.,
...

Extended mutational analysis and embryonic expression of the hereditary sacral agenesis gene HLXB9 (2000)

Hagan,
D.M.,
Ross,
A.J.,
Strachan,
T.,
...

Birth associated changes in pulmonary arterial connective tissue gene expression in the normal and hypertensive lung (2000)

Kitley,
R.M.,
Hislop,
A.A.,
Hall,
S.M.,
...

Rho GTPases and cell migration: measurement of macrophage chemotaxis (2000)

Jones,
G.E.,
Ridley,
A.J.,
Zicha,
D.

Novel molecular mechanisms of dendritic cell-induced T cell activation (2000)

Woodhead,
V.E.,
Stonehouse,
T.J.,
Binks,
M.H.,
...

In this study we have re-examined the molecular mechanisms involved in activation of T cells by dendritic cells (DC). Human peripheral blood DC (PBDC) were derived by 2 h adhesion followed by 7 day...

The development of the emetic reflex in the house musk shrew, Suncus murinus (2000)

Andrews,
P.L.R.,
Dovey,
E.,
Hockaday,
J.,
...

Neuronal intranuclear inclusion disease and juvenile parkinsonism (2000)

O'Sullivan,
J.D.,
Hanagasi,
H.A.,
Daniel,
S.E.,
...

Single channel properties of P2X ATP receptors in outside-out patches from rat hippocampal granule cells (2000)

Wong,
A.Y.C.,
Burnstock,
G.,
Gibb,
A.J.

Diffusion tensor imaging can detect and quantify corticospinal tract degeneration after stroke (2000)

Werring,
D.J.,
Toosy,
A.T.,
Clark,
C.A.,
...

The pathogenesis of lesions and normal-appearing white matter changes in multiple sclerosis: a serial diffusion MRI study (2000)

Werring,
D.J.,
Brassat,
D.,
Droogan,
A.G.,
...

Excavations in Medieval Novgorod 1998 (1999)

Reynolds,
A.J.

Different functions are required for initiation and maintenance of immortalization of rat embryo fibroblasts by SV40 large T antigen (1999)

Powell,
A.J.,
Darmon,
A.J.,
Gonos,
E.S.,
...

We have used two different, but complementary assays to characterize functions of SV40 T antigen that are necessary for its ability to immortalize rat embryo fibroblasts. In accordance with previous...

Exercise training enhances endothelial function in young men (1999)

Clarkson,
P.,
Montgomery,
H.E.,
Mullen,
M.J.,
...

OBJECTIVES: The present study was designed to assess whether exercise training can enhance endothelium-dependent dilatation in healthy young men. BACKGROUND: Exercise has been shown to reduce...

Prediction of the location and type of beta-turns in proteins using neural networks (1999)

Shepherd,
A.J.,
Gorse,
D.,
Thornton,
J.M.

A neural network has been used to predict both the location and the type of beta-turns in a set of 300 nonhomologous protein domains. A substantial improvement in prediction accuracy compared with...

Effects of recombinant human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion (1999)

Camacho Hubner,
C.,
Woods,
K.A.,
Miraki Moud,
F.,
...

Evaluation of self-taken samples for the presence of Chlamydia trachomatis infection in women using the Ligase Chain Reaction assay (1999)

Carder,
C.,
Robinson,
A.J.,
Broughton,
C.,
...

Initial findings of a hybrid positron emission tomography camera system for the identification and monitoring of ovarian cancer (1999)

Lieberman,
G.,
Hilson,
A.J.W.,
Buscombe,
J.R.,
...

Induction of myocardial nitric oxide synthase by Coxsackie B3 virus in mice (1999)

Robinson,
N.M.K.,
Zhang,
H.Y.,
Bevan,
A.L.,
...

Maternal hypothyroxinemia and c-fos and c-jun expression in rat fetal brain and placenta (1999)

Leonard,
A.J.,
Pickard,
M.R.,
Sinha,
A.K.,
...

Maternal hypothyroxinemia disrupts neurotransmitter metabolic enzymes in developing brain (1999)

Evans,
I.M.,
Sinha,
A.K.,
Pickard,
M.R.,
...

Rho family proteins and cell migration (1999)

Ridley,
A.J.,
Allen,
W.E.,
Peppelenbosch,
M.,
...

The GTP-binding proteins Rho, Rac and Cdc42 are known to regulate actin organization: Rho induces the assembly of contractile actin-based filaments such as stress fibres, Rac regulates the formation...

Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: inhibition of Cdc42-mediated filopodium formation by TNF (1999)

Peppelenbosch,
M.,
Boone,
E.,
Jones,
G.E.,
...

TNF is known to regulate macrophage (Mphi) migration, but the signaling pathways mediating this response have not been established. Here we report that stimulation of the 55-kDa TNF receptor (TNFR-1)...

Myocyte loss in chronic heart failure (1999)

Rayment,
N.B.,
Haven,
A.J.,
Madden,
B.,
...

Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection (1999)

Maini,
M.K.,
Boni,
C.,
Ogg,
G.S.,
...

Temporary extracorporeal liver support for severe acute alcoholic hepatitis using the BioLogic-DT (1999)

Ellis,
A.J.,
Hughes,
R.D.,
Nicholl,
D.,
...

Complex partial status epilepticus in late-onset MELAS (1998)

Leff,
A.P.,
Mcnabb,
A.W.,
Hanna,
M.G.,
...

Neural responses to facial and vocal expressions of fear and disgust (1998)

Phillips,
M.L.,
Young,
A.W.,
Scott,
S.K.,
...

S-nitrosoglutathione inhibits platelet activation and deposition in coronary artery saphenous vein grafts in vitro and in vivo (1998)

Salas,
E.,
Langford,
E.J.,
Marrinan,
M.T.,
...

Regional variations in Endothelin-1 and its receptor subtypes in human coronary vasculature: Pathophysiological implications in coronary disease (1998)

Dashwood,
M.R.,
Timm,
M.,
Muddle,
J.R.,
...

Distribution of endothelin-1 (ET) receptors (ET_A and ET_B) and immunoreactive ET-1 in porcine saphenous vein - carotid artery interposition grafts (1998)

Dashwood,
M.R.,
Mehta,
D.,
Izzat,
M.B.,
...

Endothelin-1 and endothelin receptors in porcine saphenous vein-carotid artery grafts (1998)

Dashwood,
M.R.,
Jeremy,
J.Y.,
Mehta,
D.,
...

Developmental regulation of lactase gene expression in pig jejunal villus-attached enterocytes (1998)

Smith,
M.W.,
Collins,
A.J.

A case of EBV-associated lymphoproliferative disease following high- dose therapy and CD34-purified autologous peripheral blood progenitor cell transplantation (1998)

Peniket,
A.J.,
Perry,
A.R.,
Williams,
C.D.,
...

True histiocytic lymphoma - A morphologic, immunohistochemical, and molecular genetic study of 13 cases (1998)

Copie-Bergman,
C.,
Wotherspoon,
A.C.,
Norton,
A.J.,
...

We describe the morphologic, immunohistologic and genotypic characteristics of 13 cases of true histiocytic lymphomas. Six cases presented with primary gastrointestinal involvement, five with...

A case of EBV-associated lymphoproliferative disease following high-dose therapy and CD34- purified autologous peripheral blood progenitor cell transplantation (1998)

Peniket,
A.J.,
Perry,
A.R.,
Williams,
C.D.,
...

A fatal case of EBV-associated lymphoproliferative disorder arising after a CD34- selectin autologous peripheral blood stem cell transplant is reported in a patient with mutliple myeloma in first...

Basal ganglia neuronal nitric oxide synthase mRNA expression in Parkinson's disease (1998)

Eve,
D.J.,
Nisbet,
A.P.,
Kingsbury,
A.E.,
...

RhoE regulates actin cytoskeleton organization and cell migration (1998)

Guasch,
R.M.,
Scambler,
P.,
Jones,
G.E.,
...

Investigation of the utility of spectral vegetation indices for determining information on coniferous forests (1998)

McDonald,
A.J.,
Gemmel,
F.,
Lewis,
P.

Plasma cytokine levels and coagulation and complement activation during use of the extracorporeal liver assist device in acute liver failure (1998)

Hughes,
R.D.,
Nicolaou,
N.,
Langley,
P.G.,
...

Deaths from low dose paracetamol poisoning (1998)

Bridger,
S.,
Henderson,
K.,
Glucksman,
E.,
...

Acetaminophen toxicity in an urban county hospital [letter; comment] (1998)

Makin,
A.J.,
Williams,
R.,
Bernal,
W.

Semi-quantitative determination of apatite anion composition for fission-track analysis using infra-red microspectroscopy. (1998)

Siddall,
R.,
Hurford,
A. J.

The structural and functional mechanisms of motor recovery: complemenatry use of diffusion tensor and functional imaging in traumatic injury of the internal capsule (1998)

Werring,
D.J.,
Clark,
C.A.,
Barker,
G.J.,
...

The molecular epidemiology of human immunodeficiency virus type 1 in six cities in Britain and Ireland (1997)

Brown,
A.J.,
Lobidel,
D.,
Wade,
C.M.,
...

Survival after a very low (<5 x 106/1) CD4+ T-cell count in individuals affected with HIV (1997)

Sabin,
C.A.,
Mocroft,
A.J.,
Bofill,
M.,
...

Cervical abnormality and sexually transmitted disease screening in human immunodeficiency virus-positive women (1997)

Olaitan,
A.,
Mocroft,
A.J.,
McCarthy,
K.,
...

Survival of AIDS Patients According to Type of AIDS-Defining Event (1997)

Mocroft,
A.J.,
Lundgren,
J.D.,
D'Arminio Monforte,
A.,
...

Thyroid hormone action in rat brain from fetal to adult life (1997)

Pickard,
M.R.,
Evans,
I.M.,
Bandopadhyay,
R.,
...

Access to the medical care one year prior to diagnosis in 100 HIV-positive women (1997)

Madge,
S.,
Olaitan,
A.,
Mocroft,
A.J.,
...

Spectrum of clinical features associated with interstitial chromosome 22q11 deletions: a European collaborative study (1997)

Ryan,
A.K.,
Goodship,
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Kanning,
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Szameitat,
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Szameitat,
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A. J.

Publishing period:

Co-authors: