Abdelwahab, A., Gardner, M., Parkash, R., Basta, M., Sapp, J., Veltmann, C., ...
Introduction: Scar-related ventricular tachycardia (VT) is often unmappable. Data regarding the outcomes of ablation for mappable vs unmappable VT are lacking. Methods: Catheter ablation of...
Camm, A.J., Sulke, N., Edvardsson, N., Ritter, P., Albers, B.A., Ruiter, J.H., ...
Aims This investigation was conducted to determine the effectiveness of several conventional overdrive pacing modalities (single rate and rate responsive pacing at various lower rates) and of four...
Brouwer, I.A., Zock, P.L., Camm, A.J., Böcker, D., Hauer, R.N.W., Wever, E.F.D., ...
Context Very-long-chain n-3 polyunsaturated fatty acids (omega-3 PUFAs) from fish are thought to reduce risk of sudden death, possibly by reducing susceptibility to cardiac arrhythmia. Objective To...
Brouwer, I.A., Zock, P.L., Camm, A.J., Böcker, D., Hauer, R.N.W., Wever, E.F.D., ...
Context Very-long-chain n-3 polyunsaturated fatty acids (omega-3 PUFAs) from fish are thought to reduce risk of sudden death, possibly by reducing susceptibility to cardiac arrhythmia. Objective To...
Katritsis, D.G., Becker, A.E., Ellenbogen, K.A., Giazitzoglou, E., Korovesis, S., Camm, A.J.
The inferior atrial extensions of the atrioventricular (AV) node have been related to the anatomic substrate of the slow pathway, but their role in AV nodal reentrant tachycardia (AVNRT) is unknown....
Sudden cardiac death: opportunities for prevention (2006)
Morgan, J.M., Cowan, J.C., Camm, A.J., McComb, J.M.
The evidence base for implantable cardioverter-defibrillator (ICD) therapy requires expansion of guidance/indications to allow UK physicians to treat a broader range of patients. The ICD clinical...
Brouwer, I.A., Zock, P.L., Camm, A.J., Bocker, D., Hauer, R.N.W., Wever, E.F.D., ...
Background Very long-chain n-3 polyunsaturated fatty acids (n-3 PUFA, also named omega-3 fatty acids) from fish may reduce risk of sudden death through reducing the susceptibility for cardiac...
Sudden cardiac death - opportunities for prevention (2005)
Morgan, J. M., Cowan, J. C., Camm, A. J., McComb, J.
The evidence base for ICD therapy requires expansion of guidance/indications to allow UK physicians to treat a broader range of patients. The ICD clinical consultees to NICE review current...
Redfern, W.S., Carlsson, L., Davis, A.S., Lynch, W.G., MacKenzie, I., Palethorpe, S., ...
Objective: To attempt to determine the relative value of preclinical cardiac electrophysiology data (in vitro and in vivo) for predicting risk of torsade de pointes (TdP) in clinical use. Methods:...
Rationale and design of a clinical trial on n-3 fatty acids and cardiac arrhythmia (2002)
Brouwer, I.A., Schouten, E.G., Zock, P.L., Katan, M.B., Camm, A.J., Bocker, D., ...
Rationale and design of a clinical trial on N-3 fatty acids and cardiac arrhythmia (SOFA) (2001)
Brouwer, I.A., Katan, M.B., Schouten, E.G., Camm, A.J., Böcker, D., Hauer, R.N.W., ...
Future role of electrical therapy for atrial fibrillation: reality for all? (2001)
Atrial fibrillation (AF) is a highly prevalent condition with a rapidly growing incidence, especially in elderly patients with underlying heart disease. The arrhythmia can be treated by a vast array...
Hammond, T.G, Carlsson, L, Davis, A.S, Lynch, W.G, MacKenzie, I, Redfern, W.S, ...
Objective: To assess current practice in the pharmaceutical industry for assessing the potential for QT interval prolongation by non-cardiovascular medicinal products. Methods: The survey was based...
The role of atrial ectopics in initiating paroxysmal atrial fibrillation (2001)
Waktare, J.E.P, Hnatkova, K, Sopher, S.M, Murgatroyd, F.D, Guo, X, Camm, A.J, ...
Aims To characterize the nature and timing of atrial ectopics preceding clinical episodes of paroxysmal atrial fibrillation. Methods and Results Holter recordings (n=177, 60 patients, 58% male, mean...
Ischaemic heart disease presenting as arrhythmias (2001)
Despite considerable progress in management over the recent years, coronary artery disease (CAD) remains the leading cause of death in the industrialised world. It is estimated that CAD is...
Task Force on Sudden Cardiac Death of the European Society of Cardiology (2001)
Priori, S.G., Aliot, E., Blomstrom-Lundqvist, C., Bossaert, L., Breithardt, G., Brugada, P., ...
Congenital and acquired long QT syndrome (2000)
Camm, A.J., Janse, M.J., Roden, D.M., Rosen, M.R., Cinca, J., Cobbe, S.M.
Yi, G, Hnatkova, K, Mahon, N.G, Keeling, P.J, Reardon, M, Camm, A.J, ...
Background Wavelet decomposition of the signal-averaged electrocardiogram has been proposed as a method of detecting small and transient irregularities hidden within the QRS complex and of overcoming...
Dofetilide for the treatment of atrial fibrillation in patients with congestive heart failure (2000)
Congenital and acquired long QT syndrome (2000)
Camm, A.J., Janse, M.J., Roden, D.M., Rosen, M.R., Cinca, J., Cobbe, S.M.
Holter sub-studies of the European myocardial infarct amiodarone trial (1998)
Malik, M., Camm, A.J., Janse, M.J., Julian, D.G., Frangin, G., Schwartz, P.J.
Amiodarone in post-infarction patients at high risk: lessons from EMIAT (1998)
Janse, M.J., Camm, A.J., Frangin, G., Julian, D.G., Malik, M., Schwartz, P.J.
Janse, M.J., Malik, M., Camm, A.J., Julian, D.G., Frangin, G.A., Schwartz, P.J.
Aims To perform a retrospective analysis of subgroups of patients enrolled into the European Myocardial Infarct Amiodarone Trial (EMIAT) in order to identify patients who might benefit from...
Atrial fibrillation: current knowledge and recommendations for management (1998)
Lévy, S., Breithardt, G., Campbell, R.W.F., Camm, A.J., Allessie, M., ...
Atrial fibrillation, a commonly encountered arrhythmia, has in recent years, been the subject of increased interest and intensive clinical research. There is also increasing awareness that atrial...
Supraventricular tachycardia: ECG diagnosis and anatomy (1997)
This paper reviews the anatomical substrates responsible for the induction and maintenance of supraventricular tachycardia and discusses the ECG findings associated with these tachycardias. The...
Katritsis, D., Hossein-Nia, M., Anastasakis, A., Poloniecki, I., Holt, D. W., Camm, A. J., ...
Background Although there remains particular concern about late malignant ventricular arrhythmias arising from myocardial damage induced by catheter ablation, the extent of myocardial injury...
Recommendations for driving of patients with implantable cardioverter defibrillators (1997)
Jung, W., Anderson, M., Camm, A. J., Jordaens, L., Petch, M. C., Rosenqvist, M., ...
Redwood, S. R., Bashir, Y., Huang, J., Leatham, E. W., Camm, A. J.
Aim Administration of intravenous magnesium sulphate has been shown to be protective during acute myocardial ischaemia and it may therefore have beneficial effects in unstable angina. The purpose of...
Redwood, S. R., Odemuyiwa, O., Hnatkova, K., Staunton, A., Poloniecki, J., Camm, A. J., ...
Aim To evaluate the predictive value and optimum dichotomy limits for different combinations of prognostic indicators for the prediction of arrhythmic events and cardiac mortality in post-infarction...
Hartikainen, J. E. K., Kautzner, J., Malik, M., Camm, A. J.
Aims The aim of this study was to compare cardiac autonomic regulation in patients with a history of paroxysmal supraventricular tachyarrhythmias, such as atrioventricular nodal reentrant tachycardia...
Fei, L., Goldman, J. H., Prasad, K., Keeling, P. J., Reardon, K., Camm, A. J., ...
Increased QT dispersion, which has been proposed as a marker of ventricular repolarization inhomogeneity, may predispose to ventricular arrhythmias. Data on QT disper sion in patients with congestive...
KATRISTIS, D., ROWLAND, E., O'NUNAIN, S., SHAKESPEARE, C. F., POLONIECKI, J., CAMM, A. J.
We studied the effects of intravenous fiecainide (2 mg.kg−1) on atrial and ventricular refractoriness and conduction during sinus rhythm, induced atrial fibrillation and atrial pacing at rates of...
KATRISTIS, D., ROWLAND, E., O'NUNAIN, S., SHAKESPEARE, C. F., POLONIECKI, J., CAMM, A. J.
We studied the effects of intravenous fiecainide (2 mg.kg−1) on atrial and ventricular refractoriness and conduction during sinus rhythm, induced atrial fibrillation and atrial pacing at rates of...
Pathophysiology of supraventricular tachycardia (1993)
Shakespeare, C. F., Anderson, M., Camm, A. J.
Supraventricular tachycardia is due to altered automaticity, triggered activity or most commonly, reentry. Atrial flutter is most frequently due to reentry with counterclockwise activation in the...
KULAKOWSKI, P., COUNIHAM, P. J., CAMM, A. J., McKENNA, W. J.
Late potentials detected by the signal-averaged ECG (SAECG) identify post-infarction patients at risk from sustained ventricular tachycardia (VT) and sudden death. Hypertrophic cardiomyopathy (HCM)...
Left ventricular energetics: heat production by the human heart (1993)
Stewart, J T, Simpson, I A, Smith, R E, Callicott, C, Gray, H H, Camm, A J
Objective: The aim was to examine the effect of coronary artery disease on human left ventricular energetics by a comparison of left ventricular oxygen consumption and heat production. The usefulness...
New class III antiarrhythmic drugs (1993)
Several new antiarrhythmic compounds with pure class III activity are currently under development and seem to possess considerable antiarrhythmic potential. The primary electrophysiological action of...
MALIK, M., ODEMUYIWA, O., POLONTECKI, J., KULAKOWSKI, P., FARRELL, T., STAUNTON, A., ...
In order to compare different criteria for the definition of late potentials in patients after myocardial infarction, three signal averaged ECG variables, duration of the signal-averaged QRS complex...
Unexplained cardiac arrest, The need for a prospective registry (1992)
PRIORI, S. G., BORGGREFE, M., CAMM, A. J., HAUER, R. N. W., KLEIN, H., ...
GRIFFITH, M. J., DE BELDER, M. A., LINKER, N. J., WARD, D. E., CAMM, A. J.
In patients with left bundle branch block pattern tachycardia, electrocardiographic criteria, based on leads V1, V2 and V6. have been shown to be effective for the diagnosis of ventricular...
How to prescribe and manage antiarrhythmic drug therapy (1992)
The pharmacological approach is the corner-stone of therapy for arrhythmia because it is non-invasive, convenient and widely available. However, the indications for antiarrhythmic therapy in general,...
KULAKOWSKI, P., GIBSON, S., WARD, J., CAMM, A. J.
The signal-averaged electrocardiogram (SAECG) identifies patients at risk of sustained ventricular tachycardia (VT), but the influence of anti-arrhythmic agents on the SAECG is not yet established....
The electrophysiological effects of flosequinan (1991)
BASHIR, Y., O'NUNAIN, S., PAUL, V. E., BUTROUS, G. S., WARD, D. E., CAMM, A. J.
We have evaluated the acute electrophysiological effects of flosequinan in 18 patients with normal ventricular function. Following intravenous infusion of flosequinan 100 mg over 1 h, mean (SD)...
The electrophysiological effects of flosequinan (1991)
BASHIR, Y., O'NUNAIN, S., PAUL, V. E., BUTROUS, G. S., WARD, D. E., CAMM, A. J.
We have evaluated the acute electrophysiological effects of flosequinan in 18 patients with normal ventricular function. Following intravenous infusion of flosequinan 100 mg over 1 h, mean (SD)...
The electrophysiological effects of flosequinan (1991)
BASHIR, Y., O'NUNAIN, S., PAUL, V. E., BUTROUS, G. S., WARD, D. E., CAMM, A. J.
We have evaluated the acute electrophysiological effects of flosequinan in 18 patients with normal ventricular function. Following intravenous infusion of flosequinan 100 mg over 1 h, mean (SD)...
Electrical ablation of junctional tachycardias showing a long RP interval (1989)
WARD, D. E., ROWLAND, E., WAINWRIGHT, R. J., CAMM, A. J.
Transvenous catheter ablation of the anomalous pathway was attempted in seven patients with drug-resistant repetitive long RF tachycardias. The patients were aged 5·5–65 years (median 20 years)...
MALIK, M., FARRELL, T., CRIPPS, T., CAMM, A. J.
Automatic analysis of heart rate variability from Hotter recordings may be invalidated by beat recognition errors and recording artefact, necessitating filtering and editing of the...
Clinical cardiac electrophysiologic evaluation of the positive inotropic agent, DPI 201-106 (1988)
BUTROUS, G. S., DEBBAS, N. M. G., ERWIN, J., DAVIES, D. W., KELLER, H. P., LUNNON, M. W., ...
DPI 201–106 is a new positive inotropic agent. The cardiac electrophysiology of 16 patients was studied before and during DPI 201–106 administration (loading dose of intravenous DPI 201–106,...
Maltz, M. B., Dymond, D. S., Nathan, A. W., Camm, A. J.
The efficacy and safety of the new cardioselective beta-blocker bisoprolol 5 mg and 10 mg once daily in the treatment of angina pectoris was compared with atenolol 100 mg once daily. 19 patients with...
Clinical cardiac electrophysiology of indoramin, a post-synaptic alpha blocker (1986)
Indoramin is a selective post-synaptic alpha blocker. Animal experiments had shown that it has antiarrhythmic effects, but whether this is due to its alpha blocking effect or some other mechanism is...
O'KEEFE, J. C., MALTZ, M. B., BUTROUS, G. S., CAMM, A. J.
Ten patients with chronic stable angina were treated with 4 incremental doses of tiapamil (200 mg, 400 mg, 600 mg and 800 mg) in a double-blind, placebo-controlled study. Treadmill exercise...
The QT interval - an indicator of the plasma and myocardial concentration of amiodarone (1985)
Bexton, R. S., Debbas, N. M. G., Du Cailar, C., Demaille, J., Puech, P., Camm, A. J.
The QT interval - an indicator of the plasma and myocardial concentration of amiodarone (1985)
Bexton, R. S., Debbas, N. M. G., Du Cailar, C., Demaille, J., Puech, P., Camm, A. J.
MARTIN, A., BENBOW, L. J., BUTROUS, G. S., LEACH, C., CAMM, A. J.
Long-term follow-up of 101 healthy elderly subjects living independently in the community has been undertaken by means of clinical examination, resting ECG and 24-hour ambulatory cardiac monitoring....
Fascicular tachycardia sensitive to calcium antagonists (1984)
WARD, D. E., NATHAN, A. W., CAMM, A. J.
Five patients with recurrent tachycardias exhibiting right bundle branch block with left axis deviation were referred for investigation. In each case, a supraventricular mechanism was suspected....
BEXTON, R. S., HELLESTRAND, K. J., NATHAN, A. W., SPURRELL, R. A. J., CAMM, A. J.
Both the electrophysiological and antiarrhythmic effects of some antiarrhythmic agents may differ markedly depending on their route of administration. Flecainide acetate, a new class 1 agent, was...
WARD, D. E., BEXTON, R., CAMM, A. J.
This study confirms the existence of accelerated conduction via a fast atrio-His pathway in patients with the so-called Lown-Ganong-Levine (LGL) syndrome. Additional slow AH pathway conduction was...
Ventriculo-atrial conduction over accessory pathways exhibiting decremental properties (1982)
Recent evidence has suggested that some anomalous ventriculo-atrial (VA) connections may exhibit decremental conduction. These pathways may provide an anatomical substrate for tachycardia, but may...
Identification of immunoreactive atrial natriuretic peptide in atrial amyloid.
Kaye, G C, Butler, M G, D'Ardenne, A J, Edmondson, S J, Camm, A J, Slavin, G
Butrous, G S, Meldrum, S J, Barton, D G, Bonnell, J A, Male, J C, Camm, A J
The effect on an implanted, multiprogrammable pacemaker of power-frequency (50 Hz) electric fields up to an intensity (unperturbed value measured at 1.7 m) of 20 kV/m were assessed in ten paced...
Identification of immunoreactive atrial natriuretic peptide in atrial amyloid.
Kaye, G C, Butler, M G, D'Ardenne, A J, Edmondson, S J, Camm, A J, Slavin, G
Butrous, G S, Meldrum, S J, Barton, D G, Bonnell, J A, Male, J C, Camm, A J
The effect on an implanted, multiprogrammable pacemaker of power-frequency (50 Hz) electric fields up to an intensity (unperturbed value measured at 1.7 m) of 20 kV/m were assessed in ten paced...
Cost implications of the British Pacing and Electrophysiology Group's recommendations for pacing.
De Belder, M. A., Linker, N. J., Jones, S., Camm, A. J., Ward, D. E.
OBJECTIVE--To compare present pacing practice with the recommendations recently published by the British Pacing and Electrophysiology Group and to assess the increase in annual budget required to...
Differential response to carotid sinus pressure during sinus rhythm and atrial fibrillation.
Hellestrand, K J, Nathan, A W, Camm, A J
In a patient who presented with syncope and palpitation left carotid sinus massage resulted in prolonged ventricular asystole during atrial fibrillation. In the same patient left carotid sinus...
Electrophysiological effects of sotalol--just another beta blocker?
Nathan, A W, Hellestrand, K J, Bexton, R S, Ward, D E, Spurrell, R A, Camm, A J
The electrophysiological effects of intravenous sotalol hydrochloride (0.4 mg/kg) were assessed in 24 patients, including 13 with the Wolff-Parkinson-White syndrome, undergoing routine...
Hellestrand, K J, Bexton, R S, Nathan, A W, Spurrell, R A, Camm, A J
The electrophysiological effects of flecainide acetate (2 mg/kg as an intravenous infusion over five minutes) were assessed in 47 patients undergoing electrophysiological study. Seven patients had...
Effect of beta blockade on exercise response after cardiac transplantation.
Bexton, R S, Milne, J R, Cory-Pearce, R, English, T A, Camm, A J
Six cardiac transplant recipients underwent maximal exercise testing before and after the administration of intravenous propranolol to assess the effect of beta blockade on their exercise heart rate...
Electrophysiological abnormalities in the transplanted human heart.
Bexton, R S, Nathan, A W, Hellestrand, K J, Cory-Pearce, R, Spurrell, R A, English, T A, ...
Fourteen relatively long term survivors of cardiac transplantation underwent systematic electrophysiological evaluation and ambulatory electrocardiographic monitoring. Six patients had prolonged...
The QT interval: a predictor of the plasma and myocardial concentrations of amiodarone.
Debbas, N M, Du Cailar, C, Bexton, R S, Demaille, J G, Camm, A J, Puech, P
A study was performed to assess whether plasma and myocardial concentrations of amiodarone correlated with changes on the surface electrocardiogram. Nine patients--seven with angina and two with...
Internal transvenous low energy cardioversion for the treatment of cardiac arrhythmias.
Nathan, A W, Bexton, R S, Spurrell, R A, Camm, A J
Low energy endocardial cardioversion was attempted in 23 patients with 30 arrhythmias, of whom only four were receiving additional drug treatment. Four had atrial flutter, five atrial fibrillation,...
Three patients with tachycardias associated with the Wolff-Parkinson-White syndrome had failed to respond to antiarrhythmic drugs and underwent transvenous ablation of accessory pathways....
Successful treatment of atrial tachycardias with flecainide acetate.
Creamer, J E, Nathan, A W, Camm, A J
Intravenous flecainide successfully terminated atrial tachycardia in three patients. Maintenance treatment with oral flecainide prevented the recurrence of tachycardia for up to three years. These...
Sinus node dysfunction associated with absence of right superior vena cava.
Camm, A J, Dymond, D, Spurrell, R A
A 41-year-old man presented with dizziness associated with sinus bradycardia and sinus arrest. An attempt to implant a transvenous pacing lead was frustrated by absence of the right superior vena...
Effect of intravenous propranolol on QT interval. A new method of assessment.
Milne, J R, Camm, A J, Ward, D E, Spurrell, R A
Changes in the QT and QTc intervals were studied in 16 patients by atrial pacing at rates of 100, 130, and 150 beats/minute. In all patients the measured QT shortened when the atrial paced rate was...
Clinical antiarrhythmic effects of amiodarone in patients with resistant paroxysmal tachycardias.
Ward, D E, Camm, A J, Spurrell, R A
Oral amiodarone, an iodine-containing antiarrhythmic agent, was administered to 72 patients with recurrent paroxysmal tachycardias. Thirty-nine patients had tachycardias associated with the...
Gaps in anterograde conduction in patients with the short PR interval, normal QRS complex syndrome.
Camm, A J, Ward, D E, Spurrell, R A
Of 8 patients with the short PR interval, normal QRS complex syndrome studied recently, 3 reported here displayed gaps in anterograde conduction. Atrial premature beats at decreasing coupling...
Ward, D E, Camm, A J, Spurrell, R A
In patients with the short PR interval, normal QRS complex syndrome, paroxysmal tachycardias are usually the result of circus movement involving the AV node and a partial or complete AV nodal bypass....
Fei, L., Anderson, M. H., Katritsis, D., Sneddon, J., Statters, D. J., Malik, M., ...
BACKGROUND--Although heart rate variability has already been studied in survivors of sudden cardiac death secondary to coronary artery disease, an assessment of heart rate variability in survivors of...
Survey of the attitudes of British physicians to pacing.
Nathan, A. W., Paul, V. E., Judge, K., Camm, A. J.
OBJECTIVES--To assess how the opinions of cardiologists, physicians, and general practitioners on the indications for permanent pacing compare with published guidelines, and to determine whether...
Heart rate variability and its relation to ventricular arrhythmias in congestive heart failure.
Fei, L., Keeling, P. J., Gill, J. S., Bashir, Y., Statters, D. J., Poloniecki, J., ...
BACKGROUND--It has been shown that heart rate variability is decreased in patients with congestive heart failure and that depressed heart rate variability is associated with a propensity to...
Relation of Helicobacter pylori infection and coronary heart disease.
Mendall, M. A., Goggin, P. M., Molineaux, N., Levy, J., Toosy, T., Strachan, D., ...
BACKGROUND--There is evidence suggesting that early life experience may influence adult risk of coronary heart disease (CHD). Chronic bacterial infections have been associated with CHD. OBJECTIVE--To...
Increased monocyte tissue factor expression in coronary disease.
Leatham, E. W., Bath, P. M., Tooze, J. A., Camm, A. J.
OBJECTIVE--To investigate whether monocyte expression of tissue factor is increased in patients with acute coronary syndromes and chronic stable angina. DESIGN--Cross sectional study of monocyte...
DDD pacing in hypertrophic cardiomyopathy: a multicentre clinical experience.
Slade, A. K., Sadoul, N., Shapiro, L., Chojnowska, L., Simon, J. P., Saumarez, R. C., ...
BACKGROUND--DDD pacing has been advocated as an effective treatment for drug refractory obstructive hypertrophic cardiomyopathy. This study reports the outcome of pacing in 56 patients with...
Katritsis, D., Heald, S., Ahsan, A., Anderson, M. H., Camm, A. J., Ward, D. E., ...
OBJECTIVE: To assess whether catheter ablation of fascicular tachycardia can be facilitated by the recording of sharp deflections arising from the mid-septum---inferior apical septum of the left...
Low energy internal cardioversion of atrial fibrillation resistant to transthoracic shocks.
Sopher, S. M., Murgatroyd, F. D., Slade, A. K., Blankoff, I., Rowland, E., Ward, D. E., ...
OBJECTIVE: To investigate the efficacy of internal cardioversion using low energy shocks delivered with a biatrial electrode configuration in chronic atrial fibrillation resistant to transthoracic...
Xie, B., Heald, S. C., Camm, A. J., Rowland, E., Ward, D. E.
OBJECTIVE: To identify possible factors associated with primary failure of radiofrequency ablation of accessory pathways or recurrence of accessory pathway conduction. PATIENTS AND METHODS:...
Relation of serum cytokine concentrations to cardiovascular risk factors and coronary heart disease.
Mendall, M. A., Patel, P., Asante, M., Ballam, L., Morris, J., Strachan, D. P., ...
OBJECTIVE: To determine whether serum concentrations of the cytokines tumour necrosis factor alpha (TNF alpha) and interleukin 6 (IL-6), which regulate C reactive protein, are associated with...
Ambulatory monitoring of pulmonary artery pressure. A preliminary clinical evaluation.
Nathan, A W, Perry, S G, Cochrane, T, Banim, S O, Spurrell, R A, Camm, A J
Traditional measurement and recording methods are inadequate for continuous monitoring of ambulatory pulmonary artery pressure. Therefore a new miniaturised solid state system has been developed and...
Griffith, M J, Linker, N J, Mehta, D, Ward, D E, Camm, A J
All eight stages of a stimulation protocol that used one then two extrastimuli from the right ventricular apex in sinus rhythm and three ventricular drive rates (100, 120, and 140 beats/min) were...
Cripps, T R, Malik, M, Farrell, T G, Camm, A J
The relation between heart rate variability, measured from standard 24 hour electrocardiogram recordings in patients convalescent after a myocardial infarction, and the occurrence of sudden death and...
Alcohol ablation of atrioventricular conduction.
Sneddon, J F, Ward, D E, Simpson, I A, Linker, N J, Wainwright, R J, Camm, A J
Transcoronary ablation of atrioventricular conduction by dehydrated alcohol was attempted in 14 patients with refractory atrial arrhythmias. Alcohol (0.5 or 1.0 ml) was delivered after selective...
Multivariate analysis to simplify the differential diagnosis of broad complex tachycardia.
Griffith, M J, De Belder, M A, Linker, N J, Ward, D E, Camm, A J
Univariate analysis has identified several criteria that aid the differential diagnosis of broad complex tachycardia. In this study of 102 consecutive patients multivariate analysis was performed to...
Dynamics of ventricular repolarisation in the congenital long QT syndromes.
Linker, N J, Camm, A J, Ward, D E
Patients with congenital QT interval prolongation are at risk of ventricular arrhythmias and sudden death. It has been suggested that the susceptibility to arrhythmias in these syndromes may be...
Catheter ablation by low energy DC shocks for successful management of atrial flutter.
O'Núnáin, S, Linker, N J, Sneddon, J F, Debbas, N M, Camm, A J, Ward, D E
OBJECTIVE--To assess the effects of low energy ablation of the substrate for atrial flutter. DESIGN--Initial retrospective analysis of patients undergoing low energy ablation of the atrioventricular...
Prognostic value of baroreflex sensitivity testing after acute myocardial infarction.
Farrell, T G, Odemuyiwa, O, Bashir, Y, Cripps, T R, Malik, M, Ward, D E, ...
BACKGROUND--Disturbances of autonomic function are recognised in both the acute and convalescent phases of myocardial infarction. Recent studies have suggested that disordered autonomic function,...
Limitations of transoesophageal echocardiography in patients with focal cerebral ischaemic events.
De Belder, M A, Lovat, L B, Tourikis, L, Leech, G, Camm, A J
OBJECTIVE--To investigate the detection rate of cardiac sources of embolism by transoesophageal echocardiography in patients with focal cerebral ischaemic events and to relate the echocardiographic...
Bashir, Y, Sneddon, J F, O'Nunain, S, Paul, V E, Gibson, S, Ward, D E, ...
OBJECTIVE--To assess the electrophysiological and antiarrhythmic effects of pharmacological load manipulation by an angiotensin converting enzyme (ACE) inhibitor (captopril) and a direct vasodilator...
Odemuyiwa, O, Farrell, T G, Malik, M, Bashir, Y, Millane, T, Cripps, T, ...
AIMS--To examine the influence of age on the prediction of sudden death after acute myocardial infarction based on heart rate variability (HRv), left ventricular ejection fraction (LVEF), and the...
Gill, J S, Hunter, G J, Gane, J, Ward, D E, Camm, A J
OBJECTIVE--Patients with exercise induced ventricular tachycardia associated with a "clinically normal" heart may have an abnormality of the regional distribution of the cardiac sympathetic nerve...
OBJECTIVE--To develop a model to assess the cost-efficacy of the implantable cardioverter defibrillator to prevent sudden death. The model must be sufficiently flexible to allow the use of cost and...
Simpson, I A, De Belder, M A, Treasure, T, Camm, A J, Pumphrey, C W
OBJECTIVES--To assess the value of transoesophageal echocardiography in patients with Marfan syndrome particularly those with suspected aortic pathology or where conventional transthoracic imaging...
Atrial adaptive rate pacing in sick sinus syndrome: effects on exercise capacity and arrhythmias.
Haywood, G A, Katritsis, D, Ward, J, Leigh-Jones, M, Ward, D E, Camm, A J
OBJECTIVE--To test the hypotheses that adaptive rate atrial (AAIR) pacing: significantly increases maximal exercise capacity, and results in significant suppression of supraventricular and...
Total atrial paralysis after permanent dual chamber cardiac pacing.
Simpson, I A, Jones, S, Camm, A J
A 73 year old woman with known ischaemic heart disease and ischaemic ventricular tachycardia underwent temporary dual chamber pacing as part of the treatment to suppress tachycardia. Insertion of a...
Fei, L, Gill, J S, Katritsis, D, Camm, A J
BACKGROUND--Idiopathic ventricular tachycardia (VT) occurs in a small but important subset of patients without clinically overt heart disease. The mechanism of the arrhythmogenesis remains unclear in...
Bashir, Y, Heald, S C, Katritsis, D, Hammouda, M, Camm, A J, Ward, D E
BACKGROUND--Radiofrequency catheter ablation of accessory arterioventricular pathways has been shown to be a highly effective treatment in patients with paroxysmal superventricular tachycardia. There...
Exercise induced vasodepressor syncope.
Sneddon, J. F., Scalia, G., Ward, D. E., McKenna, W. J., Camm, A. J., Frenneaux, M. P.
Five cases of exercise induced pure vasodepressor syncope in patients without significant structural heart disease are reported. Hypotension and symptoms of syncope or pre-syncope were induced by...
Radiofrequency catheter ablation of septal accessory atrioventricular pathways.
Xie, B, Heald, S C, Bashir, Y, Camm, A J, Ward, D E
OBJECTIVE--Septal accessory atrioventricular pathways are recognised as being more difficult to ablate than pathways in other locations. This paper describes an experience of 48 consecutive patients...
Hnatkova, K, Malik, M, Kautzner, J, Gang, Y, Camm, A J
OBJECTIVE--Normal electrocardiographic recordings were analysed to establish the influence of measurement of different numbers of electrocardiographic leads on the results of different formulas...
Cripps, T, Bennett, E D, Camm, A J, Ward, D E
The value of the high gain, signal averaged electrocardiogram combined with 24 hour electrocardiographic monitoring in the prediction of arrhythmic events was assessed in 159 patients in the first...
Mehta, D, Gilmour, S, Ward, D E, Camm, A J
The optimal atrioventricular delay at rest and during exercise was investigated in nine patients with heart block and implanted dual chamber pacemakers. All patients studied had normal left...
Diurnal variation of the QT interval--influence of the autonomic nervous system.
Bexton, R S, Vallin, H O, Camm, A J
To assess the influence of diurnal changes in the autonomic nervous system on the QT interval, 24 hour dynamic electrocardiographic monitoring was performed in six pacemaker dependent patients with...
Wiseman, M N, Giles, M S, Camm, A J
A five year old girl presented with a four month history of recurrent heart failure, which subsequently proved to be caused by endomyocardial fibrosis. There was no evidence of valvar disease....
Isolated atrial amyloid contains atrial natriuretic peptide: a report of six cases.
Kaye, G C, Butler, M G, D'Ardenne, A J, Edmondson, S J, Camm, A J, Slavin, G
Twenty five specimens of the human right atrial appendage were examined for immunoreactivity to alpha human atrial natriuretic peptide. In the electron microscope characteristic amyloid fibrils were...
Malik, M, Färbom, P, Batchvarov, V, Hnatkova, K, Camm, A J
Objective: To compare the QT/RR relation in healthy subjects in order to investigate the differences in optimum heart rate correction of the QT interval.
Effect of multisite pacing on ventricular coordination
Varma, C, O'Callaghan, P, Mahon, N G, Hnatkova, K, McKenna, W, Camm, A J, ...
Objective: To determine the effect of multisite pacing on left ventricular function.
Peripheral vascular effects of beta-adrenoceptor blockade: comparison of two agents.
Cooke, E D, Maltz, M B, Smith, R E, Bowcock, S A, Watkins, C J, Camm, A J
1. The effects of atenolol (100 mg), a beta 1-adrenoceptor blocker, and bevantolol (200 mg) were compared on heart rate, blood pressure, lung function and on the peripheral circulation in normal...
Maltz, M B, Davies, D W, Lau, C P, Creamer, J E, Banim, S O, Camm, A J
The effects of oral nitrendipine and oral propranolol, alone and in combination, on AV conduction have been examined in 11 patients with essential hypertension in whom arterial pressure was not...
Effects of propafenone on calcium currents in single ventricular myocytes of guinea-pig.
Fei, L., Gill, J. S., McKenna, W. J., Camm, A. J.
1. The effects of propafenone on the inward calcium current (ICa) were investigated in isolated single ventricular myocytes of the guinea-pig by the whole-cell clamp method. Propafenone inhibited ICa...
Interference with the pacemakers of two workers at electricity substations.
Butrous, G S, Bexton, R S, Barton, D G, Male, J C, Camm, A J
Pacemaker function was tested in two electricity substation workers exposed to high tension electric fields. High intensity electric fields induced reversion to the interference mode, producing in...
Association of Helicobacter pylori infection with coronary heart disease
Patel, P, Mendall, M A, Carrington, D, Strachan, D P, Leatham, E, Molineaux, N, ...
Obel, O A, Luddington, L, Maarouf, N, Aytemir, K, Ekwall, C, Malik, M, ...
Objective: To prospectively determine whether ventricular rate and regularity are significant determinants of the velocity and magnitude of left atrial appendage (LAA) flow.
Fatal ventricular tachycardia in association with propafenone, a new class IC antiarrhythmic agent.
Nathan, A. W., Bexton, R. S., Hellestrand, K. J., Camm, A. J.
A man with a past history of malignant ventricular arrhythmias occurring late after myocardial infarction was admitted for assessment. Monitoring revealed frequent ventricular premature beats and...
Non-invasive assessment of early cardiac involvement in systemic sclerosis.
Butrous, G. S., Dowd, P. M., Milne, J., Dymond, D. S., Caplin, J., Camm, A. J.
Twenty-eight patients with wide spectrum organ involvement of progressive systemic sclerosis but without signs or symptoms suggestive of cardiac involvement were studied by non-invasive cardiac...
Muhiddin, K. A., Turner, P., Hellestrand, K., Camm, A. J.
The efficacy of flecainide acetate in suppressing ventricular premature contractions in 14 patients was evaluated in a double-blind, cross-over, placebo controlled, randomized and balanced study....
Butrous, G. S., Maltz, M. B., O'Keefe, J., Banim, S. O., Camm, A. J.
Ventricular arrhythmias are common in patients with mitral valve prolapse. Ten patients with echocardiographically confirmed mitral valve prolapse and documented ventricular arrhythmias were included...
Oral theophylline in chronic heart failure
Al-Damluji, S., Johnston, A., Spurrell, R. A. J., Nathan, A. W., Banim, S. O., Camm, A. J.
Theophylline choline 600 mg was given as a single oral dose to nine patients in chronic left ventricular failure due to myocardial dysfunction. Cardiac output, left ventricular filling pressure...
Patel, P., Mendall, M. A., Carrington, D., Strachan, D. P., Leatham, E., Molineaux, N., ...
OBJECTIVE--To investigate the relation between seropositivity to chronic infections with Helicobacter pylori and Chlamydia pneumoniae and both coronary heart disease and cardiovascular risk factors....
Sudden cardiac death: opportunities for prevention
Morgan, J M, Cowan, J C, Camm, A J, McComb, J M
The evidence base for implantable cardioverter‐defibrillator (ICD) therapy requires expansion of guidance/indications to allow UK physicians to treat a broader range of patients. The ICD clinical...