A. J. Clarke

Publication List Details

Period

2005 - 2007

Number

53

Co-Authors

The RMS Survey: Mid-Infrared Observations of Candidate Massive YSOs in the Southern Hemisphere (2007)

Mottram, J. C., Hoare, M. G., Lumsden, S. L., Oudmaijer, R. D., Urquhart, J. S., Sheret, T. L., ...

Abridged abstract: The Red MSX Source (RMS) survey is an ongoing effort to return a large, well-selected sample of massive young stellar objects (MYSOs) within our Galaxy. A series of ground-based...

Evidence for variable outflows in the Young Stellar Object V645 Cygni (2006)

Clarke, A. J., Lumsden, S. L., Oudmaijer, R. D., Busfield, A. L., Hoare, M. G., Moore, T. J. T., ...

As part of the Red MSX Source Survey of Massive Young Stellar Objects (MYSOs) we have conducted multi-wavelength follow up observations of the well-known object V645 Cygni. We present our data on...

The RMS Survey: Radio observations of candidate massive YSOs in the southern hemisphere (2006)

Urquhart, J. S., Busfield, A. L., Hoare, M. G., Lumsden, S. L., Clarke, A. J., Moore, T. J. T., ...

The Red MSX Source (RMS) survey is a multi-wavelength program of follow-up observations designed to distinguish between genuine massive young stellar objects (MYSOs) and other embedded or dusty...

Tycho 2 stars with infrared excess in the MSX Point Source Catalogue (2005)

Clarke, A. J., Oudmaijer, R. D., Lumsden, S. L

Stars of all evolutionary phases have been found to have excess infrared emission due to the presence of circumstellar material. To identify such stars, we have positionally correlated the infrared...

Genetic risk estimation by healthcare professionals (2005)

Bonke, B., Tibben, A., Lindhout, D., Clarke, A.J., Stijnen, T.

OBJECTIVES: To assess whether healthcare professionals correctly incorporate the relevance of a favourable test outcome in a close relative when determining the level of risk for individuals at risk...

Contribution of gentamicin 2'-N-acetyltransferase to the O acetylation of peptidoglycan in Providencia stuartii.

Payie, K G, Rather, P N, Clarke, A J

A collection of Providencia stuartii mutants which either underexpress or overexpress aac(2')-Ia, the chromosomal gene coding for gentamicin 2'-N-acetyltransferase (EC 2.3.1.59), have been...

A major autolysin of Pseudomonas aeruginosa: subcellular distribution, potential role in cell growth and division and secretion in surface membrane vesicles.

Li, Z, Clarke, A J, Beveridge, T J

A 26-kDa murein hydrolase is the major autolysin of Pseudomonas aeruginosa PAO1, and its expression can be correlated with the growth and division of cells in both batch and synchronously growing...

Characterization of gentamicin 2'-N-acetyltransferase from Providencia stuartii: its use of peptidoglycan metabolites for acetylation of both aminoglycosides and peptidoglycan.

Payie, K G, Clarke, A J

The relationship between the acetylation of peptidoglycan and that of aminoglycosides in Providencia stuartii has been investigated both in vivo and in vitro. Adaptation of the assay for...

Initial characterization of two extracellular autolysins from Pseudomonas aeruginosa PAO1.

Watt, S R, Clarke, A J

Two extracellular autolysins have been detected in the spent culture supernatants of Pseudomonas aeruginosa PAO1 by using renaturing polyacrylamide gel electrophoresis. The two autolysins were...

Analysis of the sodium dodecyl sulfate-stable peptidoglycan autolysins of select gram-negative pathogens by using renaturing polyacrylamide gel electrophoresis.

Bernadsky, G, Beveridge, T J, Clarke, A J

For the first time, peptidoglycan autolysins from cellular fractions derived from sonicated cultures of Pseudomonas aeruginosa PAO1, Escherichia coli W7, Klebsiella pneumoniae CWK2, and Proteus...

Extent of peptidoglycan O acetylation in the tribe Proteeae.

Clarke, A J

The degree of peptidoglycan O acetylation in 18 strains of the different genera of the tribe Proteeae (Proteus, Providencia, and Morganella) has been determined by high-performance liquid...

Production and characterization of a monoclonal antibody to the O-acetylated peptidoglycan of Proteus mirabilis.

Gyorffy, S, Clarke, A J

A monoclonal antibody (PmPG5-3) specific for the O-acetylated peptidoglycan of Proteus mirabilis 19 was produced by an NS-1 myeloma cell line and purified from ascites fluid by a combination of...

Surface action of gentamicin on Pseudomonas aeruginosa.

Kadurugamuwa, J L, Clarke, A J, Beveridge, T J

The mode of action of gentamicin has traditionally been considered to be at the 30S ribosomal level. However, the inhibition of bacterial protein synthesis alone appears to be insufficient to...

Evidence for N----O acetyl migration as the mechanism for O acetylation of peptidoglycan in Proteus mirabilis.

Dupont, C, Clarke, A J

O-acetylated peptidoglycan was purified from Proteus mirabilis grown in the presence of specifically radiolabelled glucosamine derivatives, and the migration of the radiolabel was monitored....

In vitro synthesis and O acetylation of peptidoglycan by permeabilized cells of Proteus mirabilis.

Dupont, C, Clarke, A J

The synthesis and O acetylation in vitro of peptidoglycan by Proteus mirabilis was studied in microorganisms made permeable to specifically radiolabelled nucleotide precursors by treatment with...

Essential carboxy groups in xylanase A.

Bray, M R, Clarke, A J

An endo-1,4-beta-xylanase of Schizophyllum commune was purified to homogeneity through a modified procedure employing DEAE-Sepharose CL-6B and gel-filtration chromatography on Sephadex G-50. The role...

The composition of the cyst wall of the beet cyst-nematode Heterodera schachtii

Clarke, A. J.

1. Cyst walls of the beet cyst-nematode (Heterodera schachtii Schmidt) were obtained by sieving a suspension of crushed cysts; about 15mg of dried cyst walls was obtained from 1000 cysts. 2. The cyst...

The chemical composition of the cyst wall of the potato cyst-nematode, Heterodera rostochiensis

Clarke, A. J.

1. Cyst walls of the potato cyst-nematode (Heterodera rostochiensis Woll.) were isolated by sieving a suspension of crushed cysts. About 12mg. of dried cyst walls was obtained from 1000 cysts. 2. The...

The hatching factor of the potato-root eelworm

Clarke, A. J., Widdowson, Elizabeth

1. The hatching factor of the potato-root eelworm was concentrated from potato-root leachings by adsorption on charcoal. The crude material, extracted from charcoal with acetone, was purified by...

The chemical composition of the egg shells of the potato cyst-nematode, Heterodera rostochiensis Woll

Clarke, A. J., Cox, Patricia M., Shepherd, Audrey M.

1. Eggs of the potato cyst-nematode (Heterodera rostochiensis Woll.) were isolated by sieving a suspension of crushed cysts. Eggs were broken open by ultrasonic vibration and the egg shells separated...

Experience with screening newborns for Duchenne muscular dystrophy in Wales.

Bradley, D M, Parsons, E P, Clarke, A J

OBJECTIVES--To assess the acceptability of screening newborn boys for Duchenne muscular dystrophy. DESIGN--Screening is offered on the basis of informed consent in response to an information sheet...

Contribution of gentamicin 2'-N-acetyltransferase to the O acetylation of peptidoglycan in Providencia stuartii.

Payie, K G, Rather, P N, Clarke, A J

A collection of Providencia stuartii mutants which either underexpress or overexpress aac(2')-Ia, the chromosomal gene coding for gentamicin 2'-N-acetyltransferase (EC 2.3.1.59), have been...

A major autolysin of Pseudomonas aeruginosa: subcellular distribution, potential role in cell growth and division and secretion in surface membrane vesicles.

Li, Z, Clarke, A J, Beveridge, T J

A 26-kDa murein hydrolase is the major autolysin of Pseudomonas aeruginosa PAO1, and its expression can be correlated with the growth and division of cells in both batch and synchronously growing...

Characterization of gentamicin 2'-N-acetyltransferase from Providencia stuartii: its use of peptidoglycan metabolites for acetylation of both aminoglycosides and peptidoglycan.

Payie, K G, Clarke, A J

The relationship between the acetylation of peptidoglycan and that of aminoglycosides in Providencia stuartii has been investigated both in vivo and in vitro. Adaptation of the assay for...

Initial characterization of two extracellular autolysins from Pseudomonas aeruginosa PAO1.

Watt, S R, Clarke, A J

Two extracellular autolysins have been detected in the spent culture supernatants of Pseudomonas aeruginosa PAO1 by using renaturing polyacrylamide gel electrophoresis. The two autolysins were...

Analysis of the sodium dodecyl sulfate-stable peptidoglycan autolysins of select gram-negative pathogens by using renaturing polyacrylamide gel electrophoresis.

Bernadsky, G, Beveridge, T J, Clarke, A J

For the first time, peptidoglycan autolysins from cellular fractions derived from sonicated cultures of Pseudomonas aeruginosa PAO1, Escherichia coli W7, Klebsiella pneumoniae CWK2, and Proteus...

Extent of peptidoglycan O acetylation in the tribe Proteeae.

Clarke, A J

The degree of peptidoglycan O acetylation in 18 strains of the different genera of the tribe Proteeae (Proteus, Providencia, and Morganella) has been determined by high-performance liquid...

Production and characterization of a monoclonal antibody to the O-acetylated peptidoglycan of Proteus mirabilis.

Gyorffy, S, Clarke, A J

A monoclonal antibody (PmPG5-3) specific for the O-acetylated peptidoglycan of Proteus mirabilis 19 was produced by an NS-1 myeloma cell line and purified from ascites fluid by a combination of...

Surface action of gentamicin on Pseudomonas aeruginosa.

Kadurugamuwa, J L, Clarke, A J, Beveridge, T J

The mode of action of gentamicin has traditionally been considered to be at the 30S ribosomal level. However, the inhibition of bacterial protein synthesis alone appears to be insufficient to...

Evidence for N----O acetyl migration as the mechanism for O acetylation of peptidoglycan in Proteus mirabilis.

Dupont, C, Clarke, A J

O-acetylated peptidoglycan was purified from Proteus mirabilis grown in the presence of specifically radiolabelled glucosamine derivatives, and the migration of the radiolabel was monitored....

In vitro synthesis and O acetylation of peptidoglycan by permeabilized cells of Proteus mirabilis.

Dupont, C, Clarke, A J

The synthesis and O acetylation in vitro of peptidoglycan by Proteus mirabilis was studied in microorganisms made permeable to specifically radiolabelled nucleotide precursors by treatment with...

Essential carboxy groups in xylanase A.

Bray, M R, Clarke, A J

An endo-1,4-beta-xylanase of Schizophyllum commune was purified to homogeneity through a modified procedure employing DEAE-Sepharose CL-6B and gel-filtration chromatography on Sephadex G-50. The role...

The composition of the cyst wall of the beet cyst-nematode Heterodera schachtii

Clarke, A. J.

1. Cyst walls of the beet cyst-nematode (Heterodera schachtii Schmidt) were obtained by sieving a suspension of crushed cysts; about 15mg of dried cyst walls was obtained from 1000 cysts. 2. The cyst...

The chemical composition of the cyst wall of the potato cyst-nematode, Heterodera rostochiensis

Clarke, A. J.

1. Cyst walls of the potato cyst-nematode (Heterodera rostochiensis Woll.) were isolated by sieving a suspension of crushed cysts. About 12mg. of dried cyst walls was obtained from 1000 cysts. 2. The...

The hatching factor of the potato-root eelworm

Clarke, A. J., Widdowson, Elizabeth

1. The hatching factor of the potato-root eelworm was concentrated from potato-root leachings by adsorption on charcoal. The crude material, extracted from charcoal with acetone, was purified by...

The chemical composition of the egg shells of the potato cyst-nematode, Heterodera rostochiensis Woll

Clarke, A. J., Cox, Patricia M., Shepherd, Audrey M.

1. Eggs of the potato cyst-nematode (Heterodera rostochiensis Woll.) were isolated by sieving a suspension of crushed cysts. Eggs were broken open by ultrasonic vibration and the egg shells separated...

Experience with screening newborns for Duchenne muscular dystrophy in Wales.

Bradley, D M, Parsons, E P, Clarke, A J

OBJECTIVES--To assess the acceptability of screening newborn boys for Duchenne muscular dystrophy. DESIGN--Screening is offered on the basis of informed consent in response to an information sheet...

Familial dicentric translocation t(13;18)(p13;p11.2) ascertained by recurrent miscarriages.

Daniel, A, Perel, I D, Clarke, A J, Saville, T

A dicentric translocation is described involving chromosomes 13 and 18 in which the centromere of chromosome 13 was suppressed. The translocation was ascertained by repeated miscarriages and was...

Genetic risk: women's understanding of carrier risks in Duchenne muscular dystrophy.

Parsons, E P, Clarke, A J

This paper reports a study of 48 women (16 mothers and 32 daughters representing 28 families) who had lived with Duchenne muscular dystrophy (DMD) in their family. It looks at the way the women...

Improvements in child resistant containers.

Sibert, J R, Clarke, A J, Mitchell, M P

The numbers of children under 5 years in South Glamorgan admitted to hospital because of accidental poisoning have been analysed for 1980-4. There has been no significant fall in those taking solid...

Value of intraoperative image intensifier prints in trauma surgery.

Williams, R. L., Haddad, F. S., Clarke, A. J.

We have studied the use of image intensification in a trauma theatre over a period of 6 months with particular reference to the acquisition of intraoperative image intensifier thermal prints instead...

ALK positive inflammatory myofibroblastic tumour of the pineal region

Clarke, A J, Jacques, T S, Galloway, M J, Thom, M, Kitchen, N D, Plant, G T

Inflammatory myofibroblastic tumours (IMTs) are an uncommon spindle cell neoplasm with a dense inflammatory infiltrate, usually encountered in children. IMTs of the central nervous system are...

Hypernatraemic dehydration and necrotizing enterocolitis.

Clarke, A. J., Sibert, J. R.

Severe hypernatraemic dehydration developed over the first twelve days of life in a breastfed infant girl. Upon oral rehydration with formula milk, no acute neurological problems arose, but she...