Greater meiotic recombination in male vs. female gametes in Pinus radiata (1983)
Moran, G. F., Bell, J. C., Hilliker, A. J.
Sexually related regional variations in meiotic recombination in Pinus radiata is reported. Six different but genetically homogenous clones of P. radiata consistently showed higher melotic...
Phillips, J P, Tainer, J A, Getzoff, E D, Boulianne, G L, Kirby, K, Hilliker, A J
Mutations in Cu/Zn superoxide dismutase (SOD), a hallmark of familial amyotrophic lateral sclerosis (FALS) in humans, are shown here to confer striking neuropathology in Drosophila. Heterozygotes...
Urate-null rosy mutants of Drosophila melanogaster are hypersensitive to oxygen stress.
Hilliker, A J, Duyf, B, Evans, D, Phillips, J P
It has been proposed that uric acid is an important scavenger of deleterious oxygen radicals in biological systems [Ames, B. N., Cathcart, R., Schwiers, E. & Hochstein, P. (1981) Proc. Natl. Acad....
Phillips, J P, Campbell, S D, Michaud, D, Charbonneau, M, Hilliker, A J
The role of copper/zinc-containing superoxide dismutase (cSOD; superoxide:superoxide oxidoreductase, EC 1.15.1.1) in metabolic defense against O2 toxicity in Drosophila is examined through the...
This study attempted to assay the zygotic contribution of X chromosome genes to the genetic control of embryonic morphogenesis in Drosophila melanogaster. A systematic screen for X-linked genes which...
Clark, S. H., Hilliker, A. J., Chovnick, A.
This report presents the results of a recombination experiment designed to question the existence of special sites for the initiation or termination of a recombination heteroduplex within the region...
Genetic Localization of Foraging (For): A Major Gene for Larval Behavior in Drosophila Melanogaster
De-Belle, J. S., Hilliker, A. J., Sokolowski, M. B.
Localizing genes for quantitative traits by conventional recombination mapping is a formidable challenge because environmental variation, minor genes, and genetic markers have modifying effects on...
Hilliker, A. J., Clark, S. H., Chovnick, A.
The effect of simple DNA sequence polymorphisms on intragenic recombination in the rosy locus of Drosophila melanogaster was assayed. Two crosses were performed involving nearly identical molecular...
Eberl, D. F., Perkins, L. A., Engelstein, M., Hilliker, A. J., Perrimon, N.
Polytene section 17 of the X chromosome of Drosophila melanogaster, previously known to contain six putative lethal complementation groups important in oogenesis and embryogenesis, has here been...
Eberl, D. F., Duyf, B. J., Hilliker, A. J.
Constitutive heterochromatic regions of chromosomes are those that remain condensed through most or all of the cell cycle. In Drosophila melanogaster, the constitutive heterochromatic regions,...
Mapping Simple Repeated DNA Sequences in Heterochromatin of Drosophila Melanogaster
Lohe, A. R., Hilliker, A. J., Roberts, P. A.
Heterochromatin in Drosophila has unusual genetic, cytological and molecular properties. Highly repeated DNA sequences (satellites) are the principal component of heterochromatin. Using probes from...
Meiotic Gene Conversion Tract Length Distribution within the Rosy Locus of Drosophila Melanogaster
Hilliker, A. J., Harauz, G., Reaume, A. G., Gray, M., Clark, S. H., Chovnick, A.
Employing extensive co-conversion data for selected and unselected sites of known molecular location in the rosy locus of Drosophila melanogaster, we determine the parameters of meiotic gene...
Chaser (Csr), a New Gene Affecting Larval Foraging Behavior in Drosophila Melanogaster
Pereira, H. S., MacDonald, D. E., Hilliker, A. J., Sokolowski, M. B.
Chaser (Csr) was uncovered in a gamma mutagenesis screen to identify genes that modify the larval foraging behavior of sitters to rovers. Rover larvae have significantly longer path lenghts than...
To examine the genetic composition of proximal heterochromain in chromosome 2, the detachment of compound second autosomes, for generating proximal deficiencies, appeared a promising method. Compound...
Clark, S. H., Daniels, S., Rushlow, C. A., Hilliker, A. J., Chovnick, A.
Prior reports from this laboratory have described the experimental basis for our understanding of the genetic organization of the rosy locus (ry:3-52.0) of Drosophila melanogaster, as a bipartite...
Lu, B Y, Emtage, P C, Duyf, B J, Hilliker, A J, Eissenberg, J C
The Su(var)2-5 locus, an essential gene in Drosophila, encodes the heterochromatin-associated protein HP1. Here, we show that the Su(var)2-5 lethal period is late third instar. Maternal HP1 is still...
Yang, P, Shaver, S A, Hilliker, A J, Sokolowski, M B
Our genetic dissection of behavior has isolated scribbler (sbb), a vital gene that encodes a novel protein expressed in the embryonic and larval nervous systems and in the imaginal discs. Larvae with...
Phillips, J P, Tainer, J A, Getzoff, E D, Boulianne, G L, Kirby, K, Hilliker, A J
Mutations in Cu/Zn superoxide dismutase (SOD), a hallmark of familial amyotrophic lateral sclerosis (FALS) in humans, are shown here to confer striking neuropathology in Drosophila. Heterozygotes...
Urate-null rosy mutants of Drosophila melanogaster are hypersensitive to oxygen stress.
Hilliker, A J, Duyf, B, Evans, D, Phillips, J P
It has been proposed that uric acid is an important scavenger of deleterious oxygen radicals in biological systems [Ames, B. N., Cathcart, R., Schwiers, E. & Hochstein, P. (1981) Proc. Natl. Acad....
Phillips, J P, Campbell, S D, Michaud, D, Charbonneau, M, Hilliker, A J
The role of copper/zinc-containing superoxide dismutase (cSOD; superoxide:superoxide oxidoreductase, EC 1.15.1.1) in metabolic defense against O2 toxicity in Drosophila is examined through the...
This study attempted to assay the zygotic contribution of X chromosome genes to the genetic control of embryonic morphogenesis in Drosophila melanogaster. A systematic screen for X-linked genes which...
Clark, S. H., Hilliker, A. J., Chovnick, A.
This report presents the results of a recombination experiment designed to question the existence of special sites for the initiation or termination of a recombination heteroduplex within the region...
Genetic Localization of Foraging (For): A Major Gene for Larval Behavior in Drosophila Melanogaster
De-Belle, J. S., Hilliker, A. J., Sokolowski, M. B.
Localizing genes for quantitative traits by conventional recombination mapping is a formidable challenge because environmental variation, minor genes, and genetic markers have modifying effects on...
Hilliker, A. J., Clark, S. H., Chovnick, A.
The effect of simple DNA sequence polymorphisms on intragenic recombination in the rosy locus of Drosophila melanogaster was assayed. Two crosses were performed involving nearly identical molecular...
Eberl, D. F., Perkins, L. A., Engelstein, M., Hilliker, A. J., Perrimon, N.
Polytene section 17 of the X chromosome of Drosophila melanogaster, previously known to contain six putative lethal complementation groups important in oogenesis and embryogenesis, has here been...
Eberl, D. F., Duyf, B. J., Hilliker, A. J.
Constitutive heterochromatic regions of chromosomes are those that remain condensed through most or all of the cell cycle. In Drosophila melanogaster, the constitutive heterochromatic regions,...
Mapping Simple Repeated DNA Sequences in Heterochromatin of Drosophila Melanogaster
Lohe, A. R., Hilliker, A. J., Roberts, P. A.
Heterochromatin in Drosophila has unusual genetic, cytological and molecular properties. Highly repeated DNA sequences (satellites) are the principal component of heterochromatin. Using probes from...
Meiotic Gene Conversion Tract Length Distribution within the Rosy Locus of Drosophila Melanogaster
Hilliker, A. J., Harauz, G., Reaume, A. G., Gray, M., Clark, S. H., Chovnick, A.
Employing extensive co-conversion data for selected and unselected sites of known molecular location in the rosy locus of Drosophila melanogaster, we determine the parameters of meiotic gene...
Chaser (Csr), a New Gene Affecting Larval Foraging Behavior in Drosophila Melanogaster
Pereira, H. S., MacDonald, D. E., Hilliker, A. J., Sokolowski, M. B.
Chaser (Csr) was uncovered in a gamma mutagenesis screen to identify genes that modify the larval foraging behavior of sitters to rovers. Rover larvae have significantly longer path lenghts than...
To examine the genetic composition of proximal heterochromain in chromosome 2, the detachment of compound second autosomes, for generating proximal deficiencies, appeared a promising method. Compound...
Clark, S. H., Daniels, S., Rushlow, C. A., Hilliker, A. J., Chovnick, A.
Prior reports from this laboratory have described the experimental basis for our understanding of the genetic organization of the rosy locus (ry:3-52.0) of Drosophila melanogaster, as a bipartite...
Lu, B Y, Emtage, P C, Duyf, B J, Hilliker, A J, Eissenberg, J C
The Su(var)2-5 locus, an essential gene in Drosophila, encodes the heterochromatin-associated protein HP1. Here, we show that the Su(var)2-5 lethal period is late third instar. Maternal HP1 is still...
Yang, P, Shaver, S A, Hilliker, A J, Sokolowski, M B
Our genetic dissection of behavior has isolated scribbler (sbb), a vital gene that encodes a novel protein expressed in the embryonic and larval nervous systems and in the imaginal discs. Larvae with...