A. J. Vora

Publication List Details

Period

2002 - 2008

Number

14

Co-Authors

Cytogenetic-specific heterogeneity in the kinetics of minimal residual disease (MIRD) clearance in childhood lymphoblastic leukaemia (ALL) (2008)

Moorman, A.V., Richards, S.M., Hancock, J.P., Mitchell, C.D., Vora, A.J., Harrison, C.J., ...

Although both MRD and karyotype are powerful determinants of outcome in childhood ALL, few studies have examined the kinetics of MRD clearance by cytogenetics. In ALL2003, patients are stratified by...

Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis (2006)

Howell, O. W., Palser, A., Polito, A., Melrose, S., Zonta, B., Scheiermann, C., ...

Saltatory conduction in the nervous system is enabled through the intimate association between the leading edge of the myelin sheath and the axonal membrane to demarcate the node of Ranvier. The 186...

Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis (2006)

Howell, O. W., Palser, A., Polito, A., Melrose, S., Zonta, B., Scheiermann, C., ...

Saltatory conduction in the nervous system is enabled through the intimate association between the leading edge of the myelin sheath and the axonal membrane to demarcate the node of Ranvier. The 186...

Treatment of infants with lymphoblastic leukaemia: results of the UK Infant Protocols 1987-1999 (2002)

Chessells, J. M., Harrison, C. J., Watson, S. L., Vora, A. J., Richards, S. M.

One hundred and twenty-six infants with acute lymphoblastic leukaemia (ALL) were treated on two consecutive protocols, Infant 87 (n = 40) and Infant 92 (n = 86), in an attempt to improve the poor...

A novel myogenic regulatory circuit controls slow/cardiac troponin C gene transcription in skeletal muscle.

Parmacek, M S, Ip, H S, Jung, F, Shen, T, Martin, J F, Vora, A J, ...

The slow/cardiac troponin C (cTnC) gene is expressed in three distinct striated muscle lineages: cardiac myocytes, embryonic fast skeletal myotubes, and adult slow skeletal myocytes. We have reported...

Identification and characterization of a cardiac-specific transcriptional regulatory element in the slow/cardiac troponin C gene.

Parmacek, M S, Vora, A J, Shen, T, Barr, E, Jung, F, Leiden, J M

The slow/cardiac troponin C (cTnC) gene has been used as a model system for defining the molecular mechanisms that regulate cardiac and skeletal muscle-specific gene expression during mammalian...

A novel myogenic regulatory circuit controls slow/cardiac troponin C gene transcription in skeletal muscle.

Parmacek, M S, Ip, H S, Jung, F, Shen, T, Martin, J F, Vora, A J, ...

The slow/cardiac troponin C (cTnC) gene is expressed in three distinct striated muscle lineages: cardiac myocytes, embryonic fast skeletal myotubes, and adult slow skeletal myocytes. We have reported...

Identification and characterization of a cardiac-specific transcriptional regulatory element in the slow/cardiac troponin C gene.

Parmacek, M S, Vora, A J, Shen, T, Barr, E, Jung, F, Leiden, J M

The slow/cardiac troponin C (cTnC) gene has been used as a model system for defining the molecular mechanisms that regulate cardiac and skeletal muscle-specific gene expression during mammalian...

The clinical relevance of an isolated increase in the number of circulating hyperchromic red blood cells

Conway, A M, Vora, A J, Hinchliffe, R F

Aims: To search for laboratory evidence of hereditary spherocytosis (HS) among apparently healthy children with the chance finding of an isolated increase in hyperchromic red cells (cells with...

Human blood dendritic cells: binding to vascular endothelium and expression of adhesion molecules

BROWN, K A, BEDFORD, P, MACEY, M, McCARTHY, D A, LEROY, F, VORA, A J, ...

To investigate the binding properties of dendritic cells (DC) to vascular endothelium, a comparative analysis was undertaken of DC, monocytes and lymphocytes isolated from the blood of 25 healthy...

Enhanced binding of lymphocytes from patients with multiple sclerosis to tumour necrosis factor-alpha (TNF-α)-treated endothelial monolayers: associations with clinical relapse and adhesion molecule expression

VORA, A J, PERKIN, G D, McCOY, T, DUMONDE, D C, BROWN, K A

This study investigated the adherent properties and adhesion molecule expression of blood mononuclear cells (MNC) from a total of 84 patients with multiple sclerosis (MS). The MNC from MS patients...

IL-6 acts on endothelial cells to preferentially increase their adherence for lymphocytes

WATSON, C, WHITTAKER, S, SMITH, N, VORA, A J, DUMONDE, D C, BROWN, K A

Using a quantitative monolayer adhesion assay, the current report shows that treatment of human umbilical vein endothelial cells (HUVEC) with IL-6 increases their adhesiveness for blood lymphocytes,...

Secondary thrombocytosis.

Vora, A J, Lilleyman, J S

To estimate the incidence and causes of secondary thrombocytosis in children, a 12 month study of all patients attending a children's hospital and discovered to have a platelet count over two times...