Kaumann, A, Semmler, ABT, Molenaar, P
(-)-Noradrenaline and (-)-CGP12177 activate beta(1)-adrenoceptors through a high (H)- and low-affinity (L) site, respectively. The positive inotropic effects of (-)-noradrenaline are blunted by...
Carvedilol blocks beta(2)- more than beta(1)-adrenoceptors in human heart (2006)
Molenaar, P, Christ, T, Ravens, U, Kaumann, A
Objective: To understand the basis of the effectiveness of carvedilol in heart failure by determining its specific properties at human heart and beta(2)-adrenoceptors. Methods: The positive inotropic...
Kaumann, A, Bartel, S, Molenaar, P, Sanders, L, Burrell, K, Vetter, D, ...
Background-Catecholamines hasten cardiac relaxation through beta-adrenergic receptors, presumably by phosphorylation of several proteins, but it is unknown which receptor subtypes are involved in...
Kaumann, A, Bartel, S, Molenaar, P, Sanders, L, Burrell, K, Vetter, D, ...
Background-Catecholamines hasten cardiac relaxation through beta-adrenergic receptors, presumably by phosphorylation of several proteins, but it is unknown which receptor subtypes are involved in...