Andrea Kienle, Martin Wessner, A. Kienle, M. Wessner
Abstract Ten years of international CSCL conferences (1995–2005) provide an occasion to reflect on the formation of the CSCL community. Based on quantitative analysis of conference proceedings,...
A Model Based Analysis of Multiple Steady States in Continuos Cell Culturer (2009)
Disli, I., Kremling, A., Kienle, A.
Steady state multiplicity in continuous cell cultures is studied by means of two different types of mathematical models. The first one is a simple cybernetic model, which accounts for intracellular...
Dynamic Modeling and Simulation of Low Density Polyethylene Production - A Comparative Study (2009)
This study deals with the modelling and simulation of low density polyethylene (LDPE) production. LDPE is one of the most widely produced polymers which appears in the form of simple goods in our...
Die in diesem Bericht zusammengefassten Beiträge befassen sich mit der Computerunterstützung für die Organisation menschlicher Kommunikationsprozesse. Die Problemanalyse dieses...
Optimal Design of Experiments for Parameter Identification of Ceramic Porous Membranes (2009)
Zhang, F., Mangold, M., Kienle, A.
Six different experimental schemes for mass transfer through porous membranes are compared for the efficiency with respect to parameter identification, namely dynamic single-gas permeation, dynamic...
García Palacios, J., Kaspereit, M., Kienle, A.
A fundamental investigation is performed for integrated processes that combine continuous chromatography and isomerization reactions to produce a single (stereo-) isomer. The focus is on the...
Analyse und Auslegung chromatographischer Trennverfahren mit Rückläufen (2009)
Kaspereit, M., Sainio, T., Pieper, M., Seidel-Morgenstern, A., Kienle, A.
Herr Prof, Dr. A. Kienle, Herr Prof, Dr. K. Sundmacher
I express my gratitude to the German people for giving me the opportunity of
Kulkarni, A. A., Zeyer, K. P., Jacobs, T., Kaspereit, M., Kienle, A.
We present a new micro reactor concept which is suitable for investigations of heterogeneously catalyzed liquid phase reactions. In the set-up two reactants are mixed in a commercially available...
Sidorenko, Y., Schulze-Horsel, J., Voigt, A., Reichl, U., Kienle, A.
A distributed population balance model of influenza A virus replication in adherent Madin-Darby canine kidney cells has been developed to reproduce and interpret flow cytometry data for virus...
Nonlinear analysis of the effect of maintenance in continuous cell cultures (2008)
Vasudeva Kumar, M., Kienle, A., Zeyer, K. P., Pushpavanam, S.
New processes for recovery of acetic acid from waste water (2008)
Gangadwala, J., Radulescu, G., Kienle, A., Steyer, F., Sundmacher, K.
Global analysis of combined reaction distillation processes (2008)
Gangadwala, J., Haus, U. U., Jach, M., Kienle, A., Michaels, D., Weismantel, R.
Theoretische Analyse zum Einsatz von Additiven in der kontinuierlichen Chromatographie (2008)
Kaspereit, M., Arnell, R., Forssen, P., Seidel-Morgenstern, A., Fornstedt, T., Kienle, A.
Jacobs, T., Kaspereit, M., Zeyer, K. P., Kienle, A., Hauptmann, P.
A novel micro reactor with integrated thermal flow sensor network for real-time kinetic analysis of liquid phase chemical reactions in micro plants is presented. The sensor network consists of six...
Context-oriented communication and the design of computer-supported discursive learning (2008)
Computer-supported discursive learning (CSDL) systems for the support of asynchronous discursive learning need to fulfil specific socio-technical conditions. To understand these conditions, we...
MINLP optimization of butyl acetate synthesis (2007)
The synthesis of butyl acetate by catalytic distillation has been studied using MINLP optimization. Two process alternatives are investigated, namely a reactive distillation column (RDC) and side...
Kulkarni, A. A., Zeyer, K. P., Jacobs, T., Kienle, A.
A miniaturized-plant concept is presented for the analysis of homogeneous and heterogeneous acid-catalyzed esterification of acetic acid with butanol. The plant configuration includes a micromixer...
Zeyer, K. P., Kulkarni, A., Kienle, A., Kumar, V. M., Pushpavanam, S.
The dynamic behavior of a stand alone flash with constant heating rate and a corresponding reactor-separator system with recycle is analyzed by means of different model formulations which are...
Numerical analysis of higher order singularities in chemical process models (2007)
Krasnyk, M., Ginkel, M., Mangold, M., Kienle, A.
In this contribution, a tool is presented that allows the continuation of singularities of higher codimension for complex chemical process models. The tool is an extension of the process-modelling...
Design of simulated moving bed processes under reduced purity requirements (2007)
Kaspereit, M., Seidel-Morgenstern, A., Kienle, A.
The design of simulated moving bed chromatography under limited purity requirements is investigated. A parametric study indicates that all internal flow rates should be considered as free parameters...
Thermal effects in reactive liquid chromatography (2007)
Sainio, T., Kaspereit, M., Kienle, A., Seidel-Morgenstern, A.
Thermal effects in unsteady-state liquid phase chromatographic reactors were investigated experimentally in a thermally insulated column. In the case of an exothermic esterification reaction...
Zeyer, K. P., Kulkarni, A. A., Kienle, A., Mantravadi, V. K., Pushpavanam, S.
Modeling of evaporative separators with mass and energy balances, only, often leads to di erential algebraic systems (DAE) with di erential index 2. To overcome the problems which are associated with...
Molten Carbonate Fuel Cells : Modeling, Analysis, Simulation, and Control (2007)
Sundmacher, K., Kienle, A., Pesch, H. J., Berndt, J. F., Huppmann, G.
This is the first book being purely focused on one of the most important fuel cell technologies, Molten Carbonate Fuel Cells (MCFC). It covers different aspects of cell operation, analysis,...
A facilitator or moderator is often responsible for supporting processes and their progress in learning communities. In this article we present an approach for supporting moderators of asynchronous...
Lokaiczyk, R., Godehardt, E., Faatz, A., Goertz, M., Kienle, A., Wessner, M., ...
This work introduces an approach to discover collaboration partners and adequate advising experts in a workplace-embedded collaborative e-learning environment. Based on existing papers dealing with...
In-line analysis of chemical reactions in micro reactors using thermal mass flow sensors (2007)
Jacobs, T., Gomide, A., Kaspereit, M., Zeyer, K. P., Kienle, A., Hauptmann, P.
In this contribution we present a dual thermal mass flow sensor arrangement based on the thermo-transfer principle (calorimeter) for in-line monitoring of liquid phase chemical reactions in residence...
Radulescu, G., Paraschiv, N., Kienle, A.
The dynamic simulation of a crude oil unit is useful in understanding the unusual behavior of such a complex plant, which is induced by the dynamics of individual sub-processes in combination with...
Dynamics of Reactive Distillation Processes with Potential Liquid Phase Splitting (2007)
Gangadwala, J., Radulescu, G., Paraschiv, N., Kienle, A., Sundmacher, K.
A dynamic reactive distillation (RD) column model is developed for highly non-ideal systems with potential phase splitting. Dynamic simulations and nonlinear dynamic analysis are performed for...
Numerical bifurcation analysis of periodic solutions of population balance models (2007)
Krasnyk, M., Mangold, M., Kienle, A.
Periodic oscillations in crystallization processes have been found by various authors in theoretical and experimental studies. Such results are important in applications, because the oscillations...
Dynamics of Reaction Separation Processes in the Limit of Chemical Equilibrium (2006)
Grüner,S., Mangold,M., Kienle,A.
A new approach for analyzing and understanding the dynamics of combined reaction separation processes with fast chemical reactions was proposed recently. The approach is based on transformed...
Global Bounds on Optimal Solutions for the Production of 2,3 Dimethylbutene-1 (2006)
Gangadwala,J., Kienle,A., Haus,U. U., Michaels,D., Weismantel,R.
This paper is concerned with computer-aided optimal design of combined reaction-distillation processes. The production of solvent 2,3-dimethylbutene-1 by isomerization of 2,3-dimethylbutene-2 is...
Object-oriented modelling of large scale chemical engineering processes with ProMoT (2006)
Waschler,R., Angeles-Palacios,O., Ginkel,M., Kienle,A.
The application of the process modelling tool ProMoT to large-scale chemical engineering processes is presented. Particular emphasis in on the flexibility of the tool in terms of creating flowsheet...
Vetukuri,S. R. R., Pushpavanam,S., Zeyer,K. P., Kienle,A.
In this paper we discuss the behavior of a coupled reactor - separator system. The reactor is modeled as a CSTR sustaining an elementary first order reaction and the separator as a single stage flash...
Nonlinear Behavior of Reactor-Separator Systems with Azeotropic Mixtures (2006)
Krishna,M. V., Pushpavanam,S., Kienle,A., Vetukuri,S. R. R.
In this work, the behavior of a coupled nonlinear reactor-separator system is analyzed. The reactor is modeled as a continuous stirred tank reactor (CSTR) that sustains a first-order reaction of the...
Explicit referencing in learning chats: Needs and acceptance (2006)
Holmer, T., Kienle, A., Wessner, M.
Chat is used in many learning scenarios and platforms for synchronous communication support. Up to now evaluation of chat communication requires time consuming manual coding and analysis of the chat...
Grötsch, M., Gundermann, M., Mangold, M., Kienle, A., Sundmacher, K.
Industrial fuel cell stacks only provide very limited measurement information. To overcome this deficit, a state estimator for a molten carbonate fuel cell system is developed in this contribution....
Modeling and analysis of a plant for the production of low density polyethylene (2006)
Häfele, M., Kienle, A., Boll, M.
In this paper a detailed dynamic mathematical model of a plant for the production of low density polyethylene (LDPE) is derived. Besides the main part, a tubular reactor, the plant comprises...
Global Bounds on Optimal Solutions for the Production of 2,3 Dimethylbutene-1 (2006)
Gangadwala, J., Kienle, A., Haus, U. U., Michaels, D., Weismantel, R.
This paper is concerned with computer-aided optimal design of combined reaction-distillation processes. The production of solvent 2,3-dimethylbutene-1 by isomerization of 2,3-dimethylbutene-2 is...
Dynamics of Reaction Separation Processes in the Limit of Chemical Equilibrium (2006)
Grüner, S., Mangold, M., Kienle, A.
A new approach for analyzing and understanding the dynamics of combined reaction separation processes with fast chemical reactions was proposed recently. The approach is based on transformed...
Object-oriented modelling of large scale chemical engineering processes with ProMoT (2006)
Waschler, R., Angeles-Palacios, O., Ginkel, M., Kienle, A.
The application of the process modelling tool ProMoT to large-scale chemical engineering processes is presented. Particular emphasis in on the flexibility of the tool in terms of creating flowsheet...
Radichkov, R., Müller, T., Kienle, A., Heinrich, S., Peglow, M., Mörl, L.
Nonlinear oscillations in continuous fluidized bed spray granulation with external product classification are analyzed. Using methods from numerical bifurcation analysis the size and location of the...
Vetukuri, S. R. R., Pushpavanam, S., Zeyer, K. P., Kienle, A.
In this paper we discuss the behavior of a coupled reactor - separator system. The reactor is modeled as a CSTR sustaining an elementary first order reaction and the separator as a single stage flash...
Kulkarni, A. A., Zeyer, K. P., Jacobs, T., Kienle, A.
A microplant concept is introduced for the analysis of homogeneously and heterogeneously catalyzed liquid phase reactions. Esterification of acetic acid with butanol is considered as a benchmark...
Nonlinear Behavior of Reactor-Separator Systems with Azeotropic Mixtures (2006)
Krishna, M. V., Pushpavanam, S., Kienle, A., Vetukuri, S. R. R.
In this work, the behavior of a coupled nonlinear reactor-separator system is analyzed. The reactor is modeled as a continuous stirred tank reactor (CSTR) that sustains a first-order reaction of the...
New process for recovery of acetic acid from waste water (2006)
Gangadwala, J., Radulescu, G., Kienle, A., Steyer, F., Sundmacher, K.
This paper addresses an industrially important problem of acetic acid recovery from a waste water stream via reactive distillation route. The presence of a three-phase regime on the column stages due...
Global bounds on optimal solutions in chemical process design (2006)
Haus, U. U., Gangadwala, J., Kienle, A., Michaels, D., Seidel-Morgenstern, A., Weismantel, R.
In this paper a new approach for computing global bounds on optimal solutions of mixed-integer nonlinear programs is presented. These type of problems frequently arise in optimal design of chemical...
Dynamic simulation of reactive distillation processes with liquid-liquid phase splitting (2006)
Radulescu, G., Gangadwala, J., Kienle, A., Steyer, F., Sundmacher, K.
This work presents a modern modeling approach for reactive distillation processes with potential phase splitting. It is based on a classical model (pseudo-homogeneous) in connection with a robust and...
The ProMoT/Diana Simulation Environment (2006)
Krasnyk, M., Bondareva, K., Milokhov, O., Teplinskiy, K., Ginkel, M., Kienle, A.
We introduce the object-oriented modeling tool ProMoT and the simulation environment Diana suitable for numerical analysis of problems in chemical engineering and systems biology. The key aspects of...
State Estimation of a Molten Carbonate Fuel Cell by an Extended Kalman Filter (2006)
Grötsch, M., Mangold, M., Sheng, M., Kienle, A.
Industrial fuel cell stacks only provide very limited measurement information. To overcome this deficit, a state estimator for a molten carbonate fuel cell system is developed in this contribution....
Kumar, M. V., Raju, V. S. R., Pushpavanam, S., Kienle, A.
In this work, we analyze the nonlinear behavior of an activated sludge process (ASP). In an ASP, the wastewater stream is fed to an aerator which sustains an aerobic biochemical reaction. The...
Stationary spatially periodic and aperiodic solutions in membrane reactors (2006)
Zhang, F., Mangold, M., Kienle, A.
The formation of stationary spatially patterns is analysed for a detailed reaction mechanism of the oxidative dehydrogenation of ethane. In the first step, a simple steady-state model of an ideal...
A strategy for the spatial temperature control of a molten carbonate fuel cell system (2006)
Sheng, M., Mangold, M., Kienle, A.
The object of the paper is to develop a simple and practical control strategy for a molten carbonate fuel cell (MCFC) system. Based on a dynamic model and the control demand, a cascade control...
Sidorenko, Y., Schulze-Horsel, J., Voigt, A., Reichl, U., Kienle, A.
This presentation deals with the mathematical modeling of the influenza virus replication in mammalian cells, such as Madin Darby canine kidney (MDCK) cells, which are used in vaccine production....
Zur Integration von Reaktion und Stofftrennung (2005)
Kienle,A., Sundmacher,K., Seidel-Morgenstern,A.
Auf Grund von unerwünschten Nebenreaktionen sowie thermodynamischen Limitierungen erfordert die Gewinnung reiner Produkte neben der Durchführung der chemischer Reaktionen stets den Einsatz von...
Nichtlineare Dynamik der kontinuierlichen Wirbelschicht-Sprühgranulation (2005)
Radichkov,R., Kienle,A., Heinrich,S., Müller,T., Peglow,M., Mörl,L.
Radichkov,R., Kienle,A., Heinrich,S., Müller,T., Peglow,M., Mörl,L.
The main goal of this work is the theoretical prediction and qualitative analysis of the nonlinear behavior of fluidized bed granulation with external classification. First a new population balance...
Short-Term Scheduling of Batch Processes : a Comparative Study of Different Approaches (2005)
Mishra,B. V., Mayer,E., Raisch,J., Kienle,A.
The approaches to scheduling problem formulation in chemical engineering can be broadly classified into two categories, namely, the standard recipe approach (SRA) and the overall optimization...
Computer Aided Modeling of Chemical and Biological Systems : Methods, Tools, and Applications (2005)
Mangold,M., Angeles-Palacios,O., Ginkel,M., Kremling,A., Waschler,R., Kienle,A., ...
Computer tools can support and accelerate the development and implementation of first principle models for chemical and biological processes significantly. Several application examples illustrate...
Painuly,A., Pushpavanam,S., Kienle,A.
In a typical plant, downstream separators are coupled to upstream reactors through recycle streams. The bifurcation behavior of the coupled system is different from that of the individual units. The...
Production of Butyl Acetate by Catalytic Distillation : Theoretical and Experimental Studies (2005)
Singh,A., Hiwale,R., Mahajani,S. M., Gudi,R. D., Gangadwala,J., Kienle,A.
The esterification reaction of acetic acid with n-butanol in a continuous catalytic distillation system has been studied. The products of esterification reactions viz, water and butyl acetates are...
Balasubramaniam,P., Pushpavanam,S., Kienle,A., Balaraman,K. S.
In this work, we investigate the stability of a continuous stirred tank reactor (CSTR) coupled to an isothermal, isobaric flash. The coupling is through the recycle of the reactant-rich stream from...
Numerical Analysis of Higher-Order Singularities in Complex Chemical Process Models in ProMoT (2005)
Krasnyk,M., Ginkel,M., Mangold,M., Kienle,A.
In this contribution, a tool is presented that allows the continuation of singularities of higher codimension also for complex chemical process models. The tool is an extension of the...
Optimal Process Design for the Synthesis of 2,3-Dimethylbutene-1 (2005)
Gangadwala,J., Kienle,A., Michaels,D., Weismantel,R.
This paper is concerned with the computer-aided optimal design of reaction-distillation processes. The production of solvent 2,3-dimethylbutene-1 by isomerization of 2,3-dimethylbutene-2 is...
Nonlinear Behaviour of a Low-Density Polyethylene Tubular Reactor-Separator-Recycle System (2005)
Häfele,M., Disli-Uslu,I., Kienle,A., Krishna,V. M., Pushpavanam,S.
The aim of this work is to analyse the nonlinear behaviour of a low-density polyethylene reactor-separator-recycle system. A simplified dynamic model is derived based on the detailed model presented...
Integrated Chemical Processes (2005)
Sundmacher,K., Kienle,A., Seidel-Morgenstern,A.
This is the first book dedicated to the entire field of integrated chemical processes, covering process design, analysis, operation and control of these processes. Both the editors and authors are...
Häfele,M., Kienle,A., Boll,M., Schwibach,M.
The dynamic mathematical model of a tubular reactor for the production of low-density polyethylene (LDPE) is introduced and simulation studies of a LDPE plant are presented. The plant consists of the...
Vu,T. D., Seidel-Morgenstern,A., Grüner,S., Kienle,A.
In this paper, a new methodology for the conceptual design of chromatographic reactors is proposed and illustrated for ester hydrolysis reactions in a fixed-bed chromatographic reactor with a pulse...
State estimation of a Molten Carbonate Fuel Cell by an Extended Kalman Filter (2005)
Mangold,M., Grötsch,M., Sheng,M., Kienle,A.
Industrial fuel cell stacks only provide very limited measurement information. To overcome this deficit, a state estimator for a molten carbonate fuel cell is developed in this contribution. The...
Computer Aided Modeling of Chemical and Biological Systems : Methods, Tools, and Applications (2005)
Mangold, M., Angeles-Palacios, O., Ginkel, M., Kremling, A., Waschler, R., Kienle, A., ...
Computer tools can support and accelerate the development and implementation of first principle models for chemical and biological processes significantly. Several application examples illustrate...
Painuly, A., Pushpavanam, S., Kienle, A.
In a typical plant, downstream separators are coupled to upstream reactors through recycle streams. The bifurcation behavior of the coupled system is different from that of the individual units. The...
Production of Butyl Acetate by Catalytic Distillation : Theoretical and Experimental Studies (2005)
Singh, A., Hiwale, R., Mahajani, S. M., Gudi, R. D., Gangadwala, J., Kienle, A.
The esterification reaction of acetic acid with n-butanol in a continuous catalytic distillation system has been studied. The products of esterification reactions viz, water and butyl acetates are...
Balasubramaniam, P., Pushpavanam, S., Kienle, A., Balaraman, K. S.
In this work, we investigate the stability of a continuous stirred tank reactor (CSTR) coupled to an isothermal, isobaric flash. The coupling is through the recycle of the reactant-rich stream from...
Short-Term Scheduling of Batch Processes : a Comparative Study of Different Approaches (2005)
Mishra, B. V., Mayer, E., Raisch, J., Kienle, A.
The approaches to scheduling problem formulation in chemical engineering can be broadly classified into two categories, namely, the standard recipe approach (SRA) and the overall optimization...
Numerical Analysis of Higher-Order Singularities in Complex Chemical Process Models in ProMoT (2005)
Krasnyk, M., Ginkel, M., Mangold, M., Kienle, A.
In this contribution, a tool is presented that allows the continuation of singularities of higher codimension also for complex chemical process models. The tool is an extension of the...
Optimal Process Design for the Synthesis of 2,3-Dimethylbutene-1 (2005)
Gangadwala, J., Kienle, A., Michaels, D., Weismantel, R.
This paper is concerned with the computer-aided optimal design of reaction-distillation processes. The production of solvent 2,3-dimethylbutene-1 by isomerization of 2,3-dimethylbutene-2 is...
Nonlinear Behaviour of a Low-Density Polyethylene Tubular Reactor-Separator-Recycle System (2005)
Häfele, M., Disli-Uslu, I., Kienle, A., Krishna, V. M., Pushpavanam, S.
The aim of this work is to analyse the nonlinear behaviour of a low-density polyethylene reactor-separator-recycle system. A simplified dynamic model is derived based on the detailed model presented...
Radichkov, R., Kienle, A., Heinrich, S., Müller, T., Peglow, M., Mörl, L.
The main goal of this work is the theoretical prediction and qualitative analysis of the nonlinear behavior of fluidized bed granulation with external classification. First a new population balance...
Zur Integration von Reaktion und Stofftrennung (2005)
Kienle, A., Sundmacher, K., Seidel-Morgenstern, A.
Auf Grund von unerwünschten Nebenreaktionen sowie thermodynamischen Limitierungen erfordert die Gewinnung reiner Produkte neben der Durchführung der chemischer Reaktionen stets den Einsatz von...
Häfele, M., Kienle, A., Boll, M., Schwibach, M.
The dynamic mathematical model of a tubular reactor for the production of low-density polyethylene (LDPE) is introduced and simulation studies of a LDPE plant are presented. The plant consists of the...
Nichtlineare Dynamik der kontinuierlichen Wirbelschicht-Sprühgranulation (2005)
Radichkov, R., Kienle, A., Heinrich, S., Müller, T., Peglow, M., Mörl, L.
Vu, T. D., Seidel-Morgenstern, A., Grüner, S., Kienle, A.
In this paper, a new methodology for the conceptual design of chromatographic reactors is proposed and illustrated for ester hydrolysis reactions in a fixed-bed chromatographic reactor with a pulse...
State estimation of a Molten Carbonate Fuel Cell by an Extended Kalman Filter (2005)
Mangold, M., Grötsch, M., Sheng, M., Kienle, A.
Industrial fuel cell stacks only provide very limited measurement information. To overcome this deficit, a state estimator for a molten carbonate fuel cell is developed in this contribution. The...
Integrated Chemical Processes (2005)
Sundmacher, K., Kienle, A., Seidel-Morgenstern, A.
This is the first book dedicated to the entire field of integrated chemical processes, covering process design, analysis, operation and control of these processes. Both the editors and authors are...
Magnification—a New Look at (2005)
Biomaterials Bioengineering, A. Kienle, R. Michels, R. Hibst, J Dent Res
Light propagation in human dentin exhibits a strong directional dependence featuring the longknown optical magnification property. We hypothesized that this anisotropic effect is caused by multiple...
A general framework for analyzing and understanding the dynamics of reactive separation processes is developed. The theory is based on the assumption of simultaneous phase and reaction equilibrium....
Krishna,M. V., Pushpavanam,S., Kienle,A.
Polymerization reactions are characterized by changes in physical properties, such as viscosity, as the reaction proceeds. The effect of a conversion-dependent viscosity on the nonlinear behavior of...
Nichtlineare Dynamik in Reaktor-Separator-Systemen (2004)
Kulkarni,A. A., Pushpavanam,S., Kienle,A.
Chemische Produktionsanlagen bestehen im Wesentlichen aus Reaktions- und Separationsprozessen. In den Reaktionsprozessen werden die zugeführten Ausgangsstoffe teilweise in die gewünschten Produkte...
Nonlinear Dynamics in Reactor Separator Systems (2004)
Industrial process plants are primarily made up of two basic units, i.e. reactors and separators. The reactants are fed to the reactor unit and partially converted to products. The mixture of...
Development of physical models for the process control of a molten carbonate fuel cell system (2004)
Mangold,M., Sheng,M., Heidebrecht,P., Kienle,A., Sundmacher,K.
The subject of the paper is the development of suitable models for the process design and process control of molten carbonate fuel cell (MCFC) systems. In a first step, a rigorous dynamic, spatially...
Nonlinear model predictive control of multicomponent distillation columns using wave models (2004)
Grüner,S., Schwarzkopf,S., Disli-Uslu,I., Kienle,A., Gilles,E. D.
MTBE decomposition in a reactive distillation column (2004)
Qi,Z., Kienle,A., Stein,E., Mohl,K. D., Tuchlenski,A., Sundmacher,K.
MTBE decomposition in reactive distillation columns is investigated based on numerical simulations. Special emphasis is on the undesired side reactions. Quasi-homogeneous as well as heterogeneous...
Production of Butyl Acetate by Catalytic Distillation : Process Design Studies (2004)
Gangadwala,J., Kienle,A., Stein,E., Mahajani,S.
A simulation-based design method is employed to figure out the promising reactive distillation process configuration for the production of butyl acetate. The intrinsic kinetics developed for the...
Modeling, Simulation and Optimization of a Cross Flow Molten Carbonate Fuel Cell (2004)
Heidebrecht,P., Mangold,M., Gundermann,M., Kienle,A., Sundmacher,K.
A general framework for analyzing and understanding the dynamics of reactive separation processes is developed. The theory is based on the assumption of simultaneous phase and reaction equilibrium....
Krishna, M. V., Pushpavanam, S., Kienle, A.
Polymerization reactions are characterized by changes in physical properties, such as viscosity, as the reaction proceeds. The effect of a conversion-dependent viscosity on the nonlinear behavior of...
Nichtlineare Dynamik in Reaktor-Separator-Systemen (2004)
Kulkarni, A. A., Pushpavanam, S., Kienle, A.
Chemische Produktionsanlagen bestehen im Wesentlichen aus Reaktions- und Separationsprozessen. In den Reaktionsprozessen werden die zugeführten Ausgangsstoffe teilweise in die gewünschten Produkte...
Nonlinear Dynamics in Reactor Separator Systems (2004)
Industrial process plants are primarily made up of two basic units, i.e. reactors and separators. The reactants are fed to the reactor unit and partially converted to products. The mixture of...
Development of physical models for the process control of a molten carbonate fuel cell system (2004)
Mangold, M., Sheng, M., Heidebrecht, P., Kienle, A., Sundmacher, K.
The subject of the paper is the development of suitable models for the process design and process control of molten carbonate fuel cell (MCFC) systems. In a first step, a rigorous dynamic, spatially...
Nonlinear model predictive control of multicomponent distillation columns using wave models (2004)
Grüner, S., Schwarzkopf, S., Disli-Uslu, I., Kienle, A., Gilles, E. D.
MTBE decomposition in a reactive distillation column (2004)
Qi, Z., Kienle, A., Stein, E., Mohl, K. D., Tuchlenski, A., Sundmacher, K.
MTBE decomposition in reactive distillation columns is investigated based on numerical simulations. Special emphasis is on the undesired side reactions. Quasi-homogeneous as well as heterogeneous...
Production of Butyl Acetate by Catalytic Distillation : Process Design Studies (2004)
Gangadwala, J., Kienle, A., Stein, E., Mahajani, S.
A simulation-based design method is employed to figure out the promising reactive distillation process configuration for the production of butyl acetate. The intrinsic kinetics developed for the...
Modeling, Simulation and Optimization of a Cross Flow Molten Carbonate Fuel Cell (2004)
Heidebrecht, P., Mangold, M., Gundermann, M., Kienle, A., Sundmacher, K.
Steady-state multiplicity in bioreactors : bifurcation analysis of cybernetic models (2003)
Namjoshi,A., Kienle,A., Ramkrishna,D.
Biological systems have an additional level of complexity compared to other chemical systems because of the effects of metabolic regulation, a defining feature of biosystems. Metabolic regulation in...
MTBE decomposition in a reactive distillation column (2003)
Qi,Z., Kienle,A., Stein,E., Mohl,K. D., Tuchlenski,A., Sundmacher,K.
MTBE decomposition in reactive distillation columns is investigated with considering side reactions. Quasi-homogeneous as well as heterogeneous column models are applied for a packed column. In the...
Crystallization processes involve different kinetic processes such as nucleation of crystals, their subsequent growth and breakage. The rate equations of these kinetic processes are typically...
Time optimal control of a batch reactor using Pontryagin's Maximum Principle (2003)
Gromov,D., Mishra,B. V., Raisch,J., Kienle,A.
Time optimal control of a batch reactor is a dynamic optimisation (DO) problem. In chemical engineering, the popular trend of solving this problem involves transformation of the DO problem to a...
Nonlinear analysis of reactor separator systems involving an evaporatively cooled reactor (2003)
Waschler,R., Zeyer,K. P., Kienle,A.
The focus of this contribution is on the nonlinear analysis of a model reactor separator system. The first order reaction A to B is carried out in an adiabatic, evaporatively cooled reactor. The...
Short-term scheduling of chemical processes : an overall optimisation approach (2003)
Mishra,B. V., Mayer,E., Raisch,J., Kienle,A.
The production-scheduling problem has gained considerable importance over the last decade, especially for batch processes due to their inherent flexibility. It is a well-known fact that a good...
A two-level hybrid control strategy for the start-up of a coupled distillation plant (2003)
Itigin,A., Raisch,J., Moor,T., Kienle,A.
In this contribution, we suggest an efficient hierarchical hybrid control scheme for the start-up of a distillation plant consisting of two coupled distillation columns. The overall control task is...
Nonlinear behavior of reactor separator networks : influence of separator control structure (2003)
Chemical process plants are primarily made up of two basic units, i.e. reactors and separators. In a typical plant fresh reactants are partially converted to products in a reactor and the mixture of...
Schramm,H., Kienle,A., Kaspereit,M., Seidel-Morgenstern,A.
Recently, different strategies for improving simulated moving bed (SMB) chromatographic separation processes have been proposed, including a modulation of the feed flow and the feed concentration...
Dynamic simulation of a tubular reactor for the production of low density polyethylene (2003)
Häfele,M., Kienle,A., Boll,M., Schwibach,M.
Low density polyethylene is one of the most produced polymers in the world. In mass production there are two ways of synthesizing it, either in an autoclave or in a tubular reactor. In both types...
DIVAGUI : the graphical user interface for the simulation environment DIVA (2003)
Chebotarov,M., Ginkel,M., Häfele,M., Mangold,M., Gilles,E. D., Kienle,A., ...
Simulated moving bed process with cyclic modulation of the feed concentration (2003)
Schramm,H., Kaspereit,M., Kienle,A., Seidel-Morgenstern,A.
The improvement of the simulated moving bed (SMB) process based on the introduction of a cyclic modulation of the feed concentration is described. It is demonstrated that such a feed concentration...
Schramm,H., Grüner,S., Kienle,A.
In this contribution, simple methods are presented for controlling a simulated moving bed chromatographic process with standard PI controllers. A first method represents a simple and model-free...
Nonlinear behavior of reactor-separator networks : influence of separator control structure (2003)
In this paper we analyze the behavior of a coupled reactor separator system with reactant recycle. The reactor is represented by a CSTR and the separator is represented by a flash unit. The reactor...
Nonlinear control of a reactive distillation column (2003)
Grüner,S., Mohl,K. D., Kienle,A., Gilles,E. D., Fernholz,G., Friedrich,M.
Control of reactive distillation columns is a challenging task due to the complex dynamics arising from the coupling of reaction and separation. In this paper, asymptotically exact...
Gangadwala,J., Mankar,S., Mahajani,S., Stein,E., Kienle,A.
The esterification of acetic acid with n-butanol was studied in the presence of ion-exchange resin catalysts such as Amberlyst-15 to determine the intrinsic reaction kinetics. The effect of various...
Multiple steady states in two-phase reactors under boiling conditions (2003)
Waschler,R., Pushpavanam,S., Kienle,A.
In this paper, we analyze the nonlinear behavior of two–phase reactors under boiling conditions. First we focus on a simple nth-order reaction of the form A -> B, which allows a rigorous analytical...
Schramm,H., Kaspereit,M., Kienle,A., Seidel-Morgenstern,A.
In diesem Beitrag wird eine neue Betriebsweise für SMB Prozesse vorgestellt. Durch eine zyklische Variation der Feedkonzentration (ModiCon) während des Schaltintervalls kann die Produktivität...
Application of the Process Modeling Tool ProMoT to large-scale chemical engineering processes (2003)
Waschler,R., Angeles-Palacios,O., Ginkel,M., Kienle,A.
The application of the process modeling tool ProMoT to large-scale chemical engineering processes is presented. Particular emphasis is on the flexibility of the tool in terms of creating flowsheet...
Reactive distillation : status and future directions (2003)
In a reactive distillation column, both the chemical conversion and the distillative separation of the product mixture are carried out simultaneously. Through this integrative strategy, chemical...
In this paper, the focus is on nonlinear oscillations of ammonium sulfate crystallization. This system has been studied intensively in the past and can be viewed as a standard test system for...
Dynamical simulation of a plant for the production of low density polythylene (2003)
Häfele,M., Kienle,A., Boll,M., Mähling,F. O., Schwibach.,M.
Hochdruck-Polyethylen ist ein sehr weit verbreiteter Kunststoff, der in Rohrreaktoren produziert werden kann. Die Reaktion setzt sehr viel Reaktionswärme frei, die abgeführt werden muss. Deshalb...
Gangadwala,J., Kienle,A., Stein,E., Mahajani,S.
This paper studies reactive distillation for the synthesis of n-butyl acetate from n-butanol esterification with acetic acid over Amberlyst -15. This study is carried out to influence the unwanted...
Schramm,H., Kaspereit,M., Kienle,A., Seidel-Morgenstern,A.
Im Konferenzbeitrag wird eine neuartige und im Vergleich einfache Betriebsweise mit zyklischer Modulation der Feedkonzentration vorgestellt (ModiCon). Der Einfluss dieser Modulation auf die...
SMB chromatography with periodically modified feed concentrations (2003)
Schramm,H., Kaspereit,M., Kienle,A., Seidel-Morgenstern,A.
Preparative chromatography is an important technology to separate and purify value added products. In particular, continuous processes are attractive. Among them the elegant principle of using...
Improvement of SMB Processes by Cyclic Modulation of the Feed Concentration (2003)
Kaspereit,M., Schramm,H., Kienle,A., Seidel-Morgenstern,A.
The production of fine chemicals or pharmaceuticals frequently relies on preparative chromatographic methods. In particular, the continuous Simulated Moving Bed (SMB) process is applied to solve an...
Steady-state multiplicity in bioreactors : bifurcation analysis of cybernetic models (2003)
Namjoshi, A., Kienle, A., Ramkrishna, D.
Biological systems have an additional level of complexity compared to other chemical systems because of the effects of metabolic regulation, a defining feature of biosystems. Metabolic regulation in...
MTBE decomposition in a reactive distillation column (2003)
Qi, Z., Kienle, A., Stein, E., Mohl, K. D., Tuchlenski, A., Sundmacher, K.
MTBE decomposition in reactive distillation columns is investigated with considering side reactions. Quasi-homogeneous as well as heterogeneous column models are applied for a packed column. In the...
Crystallization processes involve different kinetic processes such as nucleation of crystals, their subsequent growth and breakage. The rate equations of these kinetic processes are typically...
Time optimal control of a batch reactor using Pontryagin's Maximum Principle (2003)
Gromov, D., Mishra, B. V., Raisch, J., Kienle, A.
Time optimal control of a batch reactor is a dynamic optimisation (DO) problem. In chemical engineering, the popular trend of solving this problem involves transformation of the DO problem to a...
Nonlinear analysis of reactor separator systems involving an evaporatively cooled reactor (2003)
Waschler, R., Zeyer, K. P., Kienle, A.
The focus of this contribution is on the nonlinear analysis of a model reactor separator system. The first order reaction A to B is carried out in an adiabatic, evaporatively cooled reactor. The...
Short-term scheduling of chemical processes : an overall optimisation approach (2003)
Mishra, B. V., Mayer, E., Raisch, J., Kienle, A.
The production-scheduling problem has gained considerable importance over the last decade, especially for batch processes due to their inherent flexibility. It is a well-known fact that a good...
A two-level hybrid control strategy for the start-up of a coupled distillation plant (2003)
Itigin, A., Raisch, J., Moor, T., Kienle, A.
In this contribution, we suggest an efficient hierarchical hybrid control scheme for the start-up of a distillation plant consisting of two coupled distillation columns. The overall control task is...
Nonlinear behavior of reactor separator networks : influence of separator control structure (2003)
Chemical process plants are primarily made up of two basic units, i.e. reactors and separators. In a typical plant fresh reactants are partially converted to products in a reactor and the mixture of...
Effect of delay on the stability of a coupled reactor-separator system (2003)
Balasubramanian, P., Kosuri, M. R., Pushpavanam, S., Kienle, A.
Schramm, H., Kienle, A., Kaspereit, M., Seidel-Morgenstern, A.
Recently, different strategies for improving simulated moving bed (SMB) chromatographic separation processes have been proposed, including a modulation of the feed flow and the feed concentration...
Dynamic simulation of a tubular reactor for the production of low density polyethylene (2003)
Häfele, M., Kienle, A., Boll, M., Schwibach, M.
Low density polyethylene is one of the most produced polymers in the world. In mass production there are two ways of synthesizing it, either in an autoclave or in a tubular reactor. In both types...
DIVAGUI : the graphical user interface for the simulation environment DIVA (2003)
Chebotarov, M., Ginkel, M., Häfele, M., Mangold, M., Gilles, E. D., Kienle, A., ...
Simulated moving bed process with cyclic modulation of the feed concentration (2003)
Schramm, H., Kaspereit, M., Kienle, A., Seidel-Morgenstern, A.
The improvement of the simulated moving bed (SMB) process based on the introduction of a cyclic modulation of the feed concentration is described. It is demonstrated that such a feed concentration...
Schramm, H., Grüner, S., Kienle, A.
In this contribution, simple methods are presented for controlling a simulated moving bed chromatographic process with standard PI controllers. A first method represents a simple and model-free...
Nonlinear behavior of reactor-separator networks : influence of separator control structure (2003)
In this paper we analyze the behavior of a coupled reactor separator system with reactant recycle. The reactor is represented by a CSTR and the separator is represented by a flash unit. The reactor...
Nonlinear control of a reactive distillation column (2003)
Grüner, S., Mohl, K. D., Kienle, A., Gilles, E. D., Fernholz, G., Friedrich, M.
Control of reactive distillation columns is a challenging task due to the complex dynamics arising from the coupling of reaction and separation. In this paper, asymptotically exact...
Gangadwala, J., Mankar, S., Mahajani, S., Stein, E., Kienle, A.
The esterification of acetic acid with n-butanol was studied in the presence of ion-exchange resin catalysts such as Amberlyst-15 to determine the intrinsic reaction kinetics. The effect of various...
Multiple steady states in two-phase reactors under boiling conditions (2003)
Waschler, R., Pushpavanam, S., Kienle, A.
In this paper, we analyze the nonlinear behavior of two–phase reactors under boiling conditions. First we focus on a simple nth-order reaction of the form A -> B, which allows a rigorous analytical...
Schramm, H., Kaspereit, M., Kienle, A., Seidel-Morgenstern, A.
In diesem Beitrag wird eine neue Betriebsweise für SMB Prozesse vorgestellt. Durch eine zyklische Variation der Feedkonzentration (ModiCon) während des Schaltintervalls kann die Produktivität...
Application of the Process Modeling Tool ProMoT to large-scale chemical engineering processes (2003)
Waschler, R., Angeles-Palacios, O., Ginkel, M., Kienle, A.
The application of the process modeling tool ProMoT to large-scale chemical engineering processes is presented. Particular emphasis is on the flexibility of the tool in terms of creating flowsheet...
Reactive distillation : status and future directions (2003)
In a reactive distillation column, both the chemical conversion and the distillative separation of the product mixture are carried out simultaneously. Through this integrative strategy, chemical...
In this paper, the focus is on nonlinear oscillations of ammonium sulfate crystallization. This system has been studied intensively in the past and can be viewed as a standard test system for...
Dynamical simulation of a plant for the production of low density polythylene (2003)
Häfele, M., Kienle, A., Boll, M., Mähling, F. O., Schwibach., M.
Hochdruck-Polyethylen ist ein sehr weit verbreiteter Kunststoff, der in Rohrreaktoren produziert werden kann. Die Reaktion setzt sehr viel Reaktionswärme frei, die abgeführt werden muss. Deshalb...
Gangadwala, J., Kienle, A., Stein, E., Mahajani, S.
This paper studies reactive distillation for the synthesis of n-butyl acetate from n-butanol esterification with acetic acid over Amberlyst -15. This study is carried out to influence the unwanted...
Schramm, H., Kaspereit, M., Kienle, A., Seidel-Morgenstern, A.
Im Konferenzbeitrag wird eine neuartige und im Vergleich einfache Betriebsweise mit zyklischer Modulation der Feedkonzentration vorgestellt (ModiCon). Der Einfluss dieser Modulation auf die...
SMB chromatography with periodically modified feed concentrations (2003)
Schramm, H., Kaspereit, M., Kienle, A., Seidel-Morgenstern, A.
Preparative chromatography is an important technology to separate and purify value added products. In particular, continuous processes are attractive. Among them the elegant principle of using...
Improvement of SMB Processes by Cyclic Modulation of the Feed Concentration (2003)
Kaspereit, M., Schramm, H., Kienle, A., Seidel-Morgenstern, A.
The production of fine chemicals or pharmaceuticals frequently relies on preparative chromatographic methods. In particular, the continuous Simulated Moving Bed (SMB) process is applied to solve an...
Improving simulated moving bed processes by cyclic modulation of the feed concentration (2002)
Schramm,H., Kaspereit,M., Kienle,A., Seidel-Morgenstern,A.
A new mode of operation for simulated moving bed chromatographic processes is presented. While conventional SMB processes are operated with constant feed concentration, a modulation of the feed...
A numerical bifurcation analysis of nonlinear oscillations in crystallization processes (2002)
The main aim of this work is the theoretical prediction and analysis of the nonlinear behavior of crystallization processes. As a first step towards the theoretical analysis a fairly simple...
Reactive separation of isobutene from C4 crack fractions by catalytic distillation processes (2002)
Qi,Z. W., Sundmacher,K., Stein,E., Kienle,A., Kolah,A.
Reactive distillation is a hybrid process where chemical reaction and distillative separation are performed in a single equipment. Even though reactive distillation could increase the selectivity of...
Yield effects in single and coupled nonlinear thermokinetic reaction systems (2002)
Zeyer,K. P., Mangold,M., Shah,S., Kienle,A., Gilles,E. D.
The influence of nonlinear dynamic effects on yield is considered for consecutive-parallel reaction schemes in a single phase CSTR. In the first part, the behavior of a single uncoupled reactor is...
Qi,Z., Sundmacher,K., Stein,E., Kienle,A.
In the C4 Olefins from steam cracking and fluid catalytic cracking there are several components. For the downstream processes, high purity isobutene or high purity C4s with very low isobutene content...
Steady state multiplicity in bioreactors: bifurcation analysis of cybernetic models (2002)
Namjoshi,A., Kienle,A., Ramkrishna,D.
Biological systems have an additional level of complexity compared to other chemical systems because of the effects of metabolic regulation. Such regulation in the form of control of enzyme synthesis...
Waschler,R., Kienle,A., Anoprienko,A., Osipova,T.
A detailed dynamic model of the Monsanto process for the production of acetic acid is presented. The nonlinear behaviour of the process is investigated and implications different control structures...
Nonlinear Analysis of gPROMS Models Using DIVA as via a CAPE ESO interface (2002)
Mangold,M., Mohl,K. D., Grüner,S., Kienle,A., Gilles,E. D.
The CAPE ESO interface of the process simulator gPROMS is used to pass model information to numerical methods contained in the simulation environment DIVA. By the interface, algorithms for the...
Reactive separation of isobutene from C4 crack fractions by catalytic distillation processes (2002)
Qi, Z. W., Sundmacher, K., Stein, E., Kienle, A., Kolah, A.
Reactive distillation is a hybrid process where chemical reaction and distillative separation are performed in a single equipment. Even though reactive distillation could increase the selectivity of...
Yield effects in single and coupled nonlinear thermokinetic reaction systems (2002)
Zeyer, K. P., Mangold, M., Shah, S., Kienle, A., Gilles, E. D.
The influence of nonlinear dynamic effects on yield is considered for consecutive-parallel reaction schemes in a single phase CSTR. In the first part, the behavior of a single uncoupled reactor is...
A numerical bifurcation analysis of nonlinear oscillations in crystallization processes (2002)
The main aim of this work is the theoretical prediction and analysis of the nonlinear behavior of crystallization processes. As a first step towards the theoretical analysis a fairly simple...
Improving simulated moving bed processes by cyclic modulation of the feed concentration (2002)
Schramm, H., Kaspereit, M., Kienle, A., Seidel-Morgenstern, A.
A new mode of operation for simulated moving bed chromatographic processes is presented. While conventional SMB processes are operated with constant feed concentration, a modulation of the feed...
Qi, Z., Sundmacher, K., Stein, E., Kienle, A.
In the C4 Olefins from steam cracking and fluid catalytic cracking there are several components. For the downstream processes, high purity isobutene or high purity C4s with very low isobutene content...
Nonlinear dynamics and control of reactive distillation processes (2002)
In some cases reactive distillation is very economical compared to a conventional process design, where reaction and separation are carried out in different processing units. Typical examples are...
Steady state multiplicity in bioreactors: bifurcation analysis of cybernetic models (2002)
Namjoshi, A., Kienle, A., Ramkrishna, D.
Biological systems have an additional level of complexity compared to other chemical systems because of the effects of metabolic regulation. Such regulation in the form of control of enzyme synthesis...
Waschler, R., Kienle, A., Anoprienko, A., Osipova, T.
A detailed dynamic model of the Monsanto process for the production of acetic acid is presented. The nonlinear behaviour of the process is investigated and implications different control structures...
Nonlinear Analysis of gPROMS Models Using DIVA as via a CAPE ESO interface (2002)
Mangold, M., Mohl, K. D., Grüner, S., Kienle, A., Gilles, E. D.
The CAPE ESO interface of the process simulator gPROMS is used to pass model information to numerical methods contained in the simulation environment DIVA. By the interface, algorithms for the...
Stein,E., Kienle,A., Kolah,A., Qi,Z., Sundmacher,K., Mohl,K. D.
Isobutene is an important starting material for many industrial syntheses. It is produced by either steam cracking of naphtha or fluid catalytic cracking of gas oil, obtaining a mixture of C4...
Mohl,K. D., Kienle,A., Sundmacher,K., Gilles,E. D.
The influence of transport limitations on kinetic instabilities in heterogeneously catalyzed reactive distillation processes is analyzed by means of two different mathematical models with finite and...
Control of Moving Bed Chromatographic Processes (2001)
Schramm,H., Grüner,S., Kienle,A., Gilles,E. D.
A new concept for the control of moving bed chromatographic processesis developed. In a first step focus is on the true moving bed process. A fairly simple method is developed for the control of this...
Linear mimo controller design for an industrial reactive distillation column (2001)
Fernholz,G., Friedrich,M., Grüner,S., Mohl,K. D., Kienle,A., Gilles,E. D.
The aim of this paper is to demonstrate the use of advanced linear controller design methods for an industrial scale reactive distillation column. The open-loop analysis of the process behavior...
Nonlinear control of an industrial reactive distillation column (2001)
Grüner,S., Mohl,K. D., Kienle,A., Gilles,E. D., Fernholz,G.
Control of reactive distillation columns is a challenging task due to the complex dynamics arising from the coupling of reaction and separation. In this paper asymptotically exact...
Nonlinear behaviour of an ideal reactor separator network with mass recycle (2001)
In this work the nonlinear behavior of a coupled reactor-separator network is analyzed using singularity and bifurcation theory. The reactor is modeled as a CSTR, which sustains an exothermic first...
Method of Lines within the Simulation Environment DIVA for Chemical Processes (2001)
Köhler,R., Mohl,K. D., Schramm,H., Zeitz,M., Kienle,A., Mangold,M., ...
In chemical engineering, detailed process modeling, simulation, nonlinear analysis, and optimization of single process units as well as integrated production plants are issues of growing importance....
New Control Strategies for Moving Bed Chromatographic Processes (2001)
Schramm,H., Grüner,S., Kienle,A.
Two different control strategies for Moving Bed chromatographic processes are developed and applied to True as well as Simulated Moving Bed processes. The first method represents an inferential...
Diehl,M., Uslu,I., Findeisen,R., Schwarzkopf,S., Allgöwer,F., Bock,H. G., ...
The purpose of this paper is an experimental proof-of-concept of the application of NMPC for large scale systems using specialized dynamic optimization strategies. For this aim we investigate the...
Stein, E., Kienle, A., Kolah, A., Qi, Z., Sundmacher, K., Mohl, K. D.
Isobutene is an important starting material for many industrial syntheses. It is produced by either steam cracking of naphtha or fluid catalytic cracking of gas oil, obtaining a mixture of C4...
Mohl, K. D., Kienle, A., Sundmacher, K., Gilles, E. D.
The influence of transport limitations on kinetic instabilities in heterogeneously catalyzed reactive distillation processes is analyzed by means of two different mathematical models with finite and...
Control of Moving Bed Chromatographic Processes (2001)
Schramm, H., Grüner, S., Kienle, A., Gilles, E. D.
A new concept for the control of moving bed chromatographic processesis developed. In a first step focus is on the true moving bed process. A fairly simple method is developed for the control of this...
Linear mimo controller design for an industrial reactive distillation column (2001)
Fernholz, G., Friedrich, M., Grüner, S., Mohl, K. D., Kienle, A., Gilles, E. D.
The aim of this paper is to demonstrate the use of advanced linear controller design methods for an industrial scale reactive distillation column. The open-loop analysis of the process behavior...
Nonlinear control of an industrial reactive distillation column (2001)
Grüner, S., Mohl, K. D., Kienle, A., Gilles, E. D., Fernholz, G.
Control of reactive distillation columns is a challenging task due to the complex dynamics arising from the coupling of reaction and separation. In this paper asymptotically exact...
Nonlinear behaviour of an ideal reactor separator network with mass recycle (2001)
In this work the nonlinear behavior of a coupled reactor-separator network is analyzed using singularity and bifurcation theory. The reactor is modeled as a CSTR, which sustains an exothermic first...
Method of Lines within the Simulation Environment DIVA for Chemical Processes (2001)
Köhler, R., Mohl, K. D., Schramm, H., Zeitz, M., Kienle, A., Mangold, M., ...
In chemical engineering, detailed process modeling, simulation, nonlinear analysis, and optimization of single process units as well as integrated production plants are issues of growing importance....
New Control Strategies for Moving Bed Chromatographic Processes (2001)
Schramm, H., Grüner, S., Kienle, A.
Two different control strategies for Moving Bed chromatographic processes are developed and applied to True as well as Simulated Moving Bed processes. The first method represents an inferential...
Diehl, M., Uslu, I., Findeisen, R., Schwarzkopf, S., Allgöwer, F., Bock, H. G., ...
The purpose of this paper is an experimental proof-of-concept of the application of NMPC for large scale systems using specialized dynamic optimization strategies. For this aim we investigate the...
Reactive separation of C4 streams using coupled reactive distillation columns - a case study (2000)
Stein,E., Kienle,A., Sundmacher,K.
A case study is presented on separating isobutene form a mixture of hydrocarbons, with the clean-fuel additive, MTBE, as an intermediate product.
Nonlinear computation using DIVA - methods and applications (2000)
Mangold,M., Kienle,A., Mohl,K. D., Gilles,E. D.
Methods for 1-parameter continuation and stability analysis of periodic solutions as well as 2-parameter continuation of Hopf and limit bifurcation points have been added to the dynamic flowsheet...
Automatic generation of switching start-up schemes for chemical processes (2000)
Klein,E., Itigin,A., Raisch,J., Kienle,A.
This paper explains how modern techniques from the areas of hybrid and discrete event systems theory can be used to automatize the start-up procedure of chemical processes. As an application example...
Separation using coupled reactive distillation columns (2000)
Stein, E., Kienle, A., Sundmacher, K.
A case study is presented on separating isobutene form a mixture of hydrocarbons, with the clean-fuel additive, MTBE, as an intermediate product.
A uniform approach to nonlinear model reduction for nonreactive as well as reactive distillation processes with fast reversible chemical reactions in the liquid phase is presented. The approach is...
Nonlinear computation using DIVA - methods and applications (2000)
Mangold, M., Kienle, A., Mohl, K. D., Gilles, E. D.
Methods for 1-parameter continuation and stability analysis of periodic solutions as well as 2-parameter continuation of Hopf and limit bifurcation points have been added to the dynamic flowsheet...
A new approach to the development of low-order dynamic models for multicomponent distillation processes is presented. This approach makes direct use of well known spatio-temporal pattern formation...
Automatic generation of switching start-up schemes for chemical processes (2000)
Klein, E., Itigin, A., Raisch, J., Kienle, A.
This paper explains how modern techniques from the areas of hybrid and discrete event systems theory can be used to automatize the start-up procedure of chemical processes. As an application example...
Production of high purity isobutene using coupled reactive distillation columns (2000)
Stein, E., Kienle, A., Kolah, A., Qi, Z., Sundmacher, K., Mohl, K. D.
Waschler,R., Kienle,A., Sviatnyi,S., Gilles,E. D., Anoprienko,A., Osipova,T.
A special modeling and simulation approach is required to account for potential discrete events during the simulation of chemical plants. In the case of a reactor for the production of acetic acid...
Object-oriented modeling of distillation processes (1999)
Tränkle,F., Kienle,A., Mohl,K. D., Zeitz,M., Gilles,E. D.
The process modeling tool PROMOT supports the object-oriented and equation-based modeling of chemical processes for the process simulation environment DIVA. This contribution demonstrates the...
Optimization of a reactor network for ethylene glycol synthesis : an algorithmic approach (1999)
Stein,E., Kienle,A., Esparta,A. R., Mohl,K. D., Gilles,E. D.
This contribution is concerned with reactor network synthesis for the production of ethylene glycol by hydration of ethylene oxide, which is an industrially relevant process. This reaction is not...
Dynamic optimization of multicomponent distillation processes (1999)
Stein,E., Kienle,A., Gilles,E. D.
Increasing quality requirements and decreasing production periods demand the real-time optimization of simple units as well as of wholeplants in the process industry. In this work a multicomponent...
Klein,E., Raisch,J., Kienle,A., Wehlan,H.
Der Beitrag beschreibt die Synthese einer ereignisdiskreten Regelung für den Anfahrvorgang einer Destillationskolonne. Der Ansatz basiert auf Methoden der hybriden und ereignisdiskreten...
Low-order dynamic models for two coupled distillation columns (1999)
Kienle,A., Stein,E., Rehm,A., Kloppenburg,E.
Nonlinear low-order models are developed for two coupled distillation columns separating a ternary mixture of methanol, ethanol and 1-propanol. The approach is based on well-known spatio temporal...
Kienle,A., Pfisterer,F., Waschler,R., Sviatnyi,S., Gilles,E. D., Anoprienko,A., ...
A two-phase model of a reactor for the production of acetic acid is presented and simulation results are compared to results obtained for a one-phase model described in a previous study. It is shown...
Mohl,K. D., Kienle,A., Gilles,E. D., Rapmund,P., Sundmacher,K., Hoffmann,U.
In this contribution, the nonlinear dynamic behaviour of reactive distillation columns for the production of MTBE and TAME is studied. The focus is on steady state multiplicity and a rigorous...
Coupled reaction zones in a circulation loop reactor (1999)
Mangold,M., Kienle,A., Gilles,E. D., Richter,M., Roschka,E.
This work deals with the behavior of coupled reaction fronts in a novel type of catalytic fixed bed reactor, the so-called circulation loop reactor. Experiments in a laboratory scale reactor, which...
Waschler, R., Kienle, A., Sviatnyi, S., Gilles, E. D., Anoprienko, A., Osipova, T.
A special modeling and simulation approach is required to account for potential discrete events during the simulation of chemical plants. In the case of a reactor for the production of acetic acid...
Object-oriented modeling of distillation processes (1999)
Tränkle, F., Kienle, A., Mohl, K. D., Zeitz, M., Gilles, E. D.
The process modeling tool PROMOT supports the object-oriented and equation-based modeling of chemical processes for the process simulation environment DIVA. This contribution demonstrates the...
Optimization of a reactor network for ethylene glycol synthesis : an algorithmic approach (1999)
Stein, E., Kienle, A., Esparta, A. R., Mohl, K. D., Gilles, E. D.
This contribution is concerned with reactor network synthesis for the production of ethylene glycol by hydration of ethylene oxide, which is an industrially relevant process. This reaction is not...
Dynamic optimization of multicomponent distillation processes (1999)
Stein, E., Kienle, A., Gilles, E. D.
Increasing quality requirements and decreasing production periods demand the real-time optimization of simple units as well as of wholeplants in the process industry. In this work a multicomponent...
Klein, E., Raisch, J., Kienle, A., Wehlan, H.
Der Beitrag beschreibt die Synthese einer ereignisdiskreten Regelung für den Anfahrvorgang einer Destillationskolonne. Der Ansatz basiert auf Methoden der hybriden und ereignisdiskreten...
Low-order dynamic models for two coupled distillation columns (1999)
Kienle, A., Stein, E., Rehm, A., Kloppenburg, E.
Nonlinear low-order models are developed for two coupled distillation columns separating a ternary mixture of methanol, ethanol and 1-propanol. The approach is based on well-known spatio temporal...
Kienle, A., Pfisterer, F., Waschler, R., Sviatnyi, S., Gilles, E. D., Anoprienko, A., ...
A two-phase model of a reactor for the production of acetic acid is presented and simulation results are compared to results obtained for a one-phase model described in a previous study. It is shown...
Mohl, K. D., Kienle, A., Gilles, E. D., Rapmund, P., Sundmacher, K., Hoffmann, U.
In this contribution, the nonlinear dynamic behaviour of reactive distillation columns for the production of MTBE and TAME is studied. The focus is on steady state multiplicity and a rigorous...
Coupled reaction zones in a circulation loop reactor (1999)
Mangold, M., Kienle, A., Gilles, E. D., Richter, M., Roschka, E.
This work deals with the behavior of coupled reaction fronts in a novel type of catalytic fixed bed reactor, the so-called circulation loop reactor. Experiments in a laboratory scale reactor, which...
Nonlinear inferential control of an autonomous periodic fixed-bed reactor (1998)
Hua,X., Mangold,M., Kienle,A., Gilles,E. D.
This paper deals with the control of an autonomous periodic fixed-bed reactor, which is called circulation loop reactor (CLR). This process can be described by a distributed parameter system with...
Analyse nichtlinearer Phänomene bei verfahrenstechnischen Prozessen (1998)
Mangold,M., Mohl,K., Kienle,A., Gilles,E. D.
Continuation methods combined with the concepts of stability and bifurcation theory are now widely accepted for the analysis of chemical engineering systems. Nonlinear analysis can lead to an...
State profile estimation of an autothermal periodic fixed-bed reactor (1998)
Mangold,M., Kienle,A., Gilles,E. D.
In this paper, the state profile estimation of a novel autothermal fixed-bed reactor (called circulation loop reactor, CLR), which can be operated as an autonomous periodic system, is studied. Since...
Stabilization of an unstable distillation column (1998)
Dorn,C., Güttinger,T. E., Wells,G. J., Morari,M., Kienle,A., Klein,E., ...
Bekiaris et al. (Ind. Eng. Chem. Res. 1993, 32 (9), 2023) explained the existence of multiple steady states in homogeneous azeotropic distillation on the basis of the analysis of columns with...
Optimization of a reactor network for ethylene glycol synthesis (1998)
Stein,E., Kienle,A., Esparta,R., Mohl,K. D., Gilles,E. D.
This contribution is concerned with the energy optimal process design for ethylene glycol synthesis which is an industrially relevant process. A systematical approach is developed based on the...
Nonlinear computation using DIVA : methods and applications (1998)
Mangold,M., Kienle,A., Gilles,E. D., Mohl,K. D.
Methods for the 1-parameter continuation and stability analysis of periodic solutions as well as 2-parameter continuation of Hopf and limit bifurcation points have been added to the dynamic flowsheet...
Klein,E., Kienle,A., Raisch,J.
This paper addresses the problem of synthesizing a supervisory control scheme for the start-up procedure of a distillation column. We use techniques from the areas of hybrid and discrete event...
Mohl,K. D., Kienle,A., Gilles,E. D., Rapmund,P., Sundmacher,K., Hoffmann,U.
In this contribution, the nonlinear dynamic behavior of reactive distillation columns for the production of MTBE and TAME is studied. The focus is on steady state multiplicity and a rigorous...
Nonlinear inferential control of an autonomous periodic fixed-bed reactor (1998)
Hua, X., Mangold, M., Kienle, A., Gilles, E. D.
This paper deals with the control of an autonomous periodic fixed-bed reactor, which is called circulation loop reactor (CLR). This process can be described by a distributed parameter system with...
Analyse nichtlinearer Phänomene bei verfahrenstechnischen Prozessen (1998)
Mangold, M., Mohl, K., Kienle, A., Gilles, E. D.
Continuation methods combined with the concepts of stability and bifurcation theory are now widely accepted for the analysis of chemical engineering systems. Nonlinear analysis can lead to an...
State profile estimation of an autothermal periodic fixed-bed reactor (1998)
Mangold, M., Kienle, A., Gilles, E. D.
In this paper, the state profile estimation of a novel autothermal fixed-bed reactor (called circulation loop reactor, CLR), which can be operated as an autonomous periodic system, is studied. Since...
Stabilization of an unstable distillation column (1998)
Dorn, C., Güttinger, T. E., Wells, G. J., Morari, M., Kienle, A., Klein, E., ...
Bekiaris et al. (Ind. Eng. Chem. Res. 1993, 32 (9), 2023) explained the existence of multiple steady states in homogeneous azeotropic distillation on the basis of the analysis of columns with...
Optimization of a reactor network for ethylene glycol synthesis (1998)
Stein, E., Kienle, A., Esparta, R., Mohl, K. D., Gilles, E. D.
This contribution is concerned with the energy optimal process design for ethylene glycol synthesis which is an industrially relevant process. A systematical approach is developed based on the...
Nonlinear computation using DIVA : methods and applications (1998)
Mangold, M., Kienle, A., Gilles, E. D., Mohl, K. D.
Methods for the 1-parameter continuation and stability analysis of periodic solutions as well as 2-parameter continuation of Hopf and limit bifurcation points have been added to the dynamic flowsheet...
Klein, E., Kienle, A., Raisch, J.
This paper addresses the problem of synthesizing a supervisory control scheme for the start-up procedure of a distillation column. We use techniques from the areas of hybrid and discrete event...
A new model reduction approach for multicomponent separation processes is presented. This approach makes directly use of well-known spatio temporal pattern formation also termed as nonlinear wave...
Mohl, K. D., Kienle, A., Gilles, E. D., Rapmund, P., Sundmacher, K., Hoffmann, U.
In this contribution, the nonlinear dynamic behavior of reactive distillation columns for the production of MTBE and TAME is studied. The focus is on steady state multiplicity and a rigorous...
Noninvasive determination of the optical properties of two-layered turbid media (1998)
Kienle, A., Patterson, M. S., Dognitz, N., Bays, R., Wagnieres, G.
Nonlinear dynamics of reactive distillation processes for the production of fuel ethers (1997)
Mohl,K. D., Kienle,A., Gilles,E. D., Rapmund,P., Sundmacher,K., Hoffmann,U.
A rigorous numerical bifurcation and stability analysis of reactive distillation processes for the production of fuel ethers MTBE and TAME is presented. The bifurcation behaviour is studied in terms...
Nonlinear dynamics of reactive distillation processes for the production of fuel ethers (1997)
Mohl, K. D., Kienle, A., Gilles, E. D., Rapmund, P., Sundmacher, K., Hoffmann, U.
A rigorous numerical bifurcation and stability analysis of reactive distillation processes for the production of fuel ethers MTBE and TAME is presented. The bifurcation behaviour is studied in terms...
Nichtlineare Wellenphänomene und Stabilität stationärer Zustände in Destillationskolonnen (1997)
Im ersten Teil der vorliegenden Arbeit wird auf der Basis wandernder Stoffaustauschfronten eine umfangreiche Theorie des nichtlinearen dynamischen Verhaltens von Stofftrennprozessen für homogene...
Some aspects of integrated process operation (1996)
Gilles,E. D., Lauschke,G., Kienle,A., Storz,M.
The aspect of process integration is examined on two levels. On the lower level, different unit operations, like reaction and heat recovery or reaction and separation, are integrated into...
Some aspects of integrated process operation (1996)
Gilles, E. D., Lauschke, G., Kienle, A., Storz, M.
The aspect of process integration is examined on two levels. On the lower level, different unit operations, like reaction and heat recovery or reaction and separation, are integrated into...
Multiple steady states in binary distillation : theoretical and experimental results (1995)
Kienle,A., Groebel,M., Gilles,E. D.
Steady-state multiplicity and instability in distillation is studied theoretically and experimentally for columns with volumetric reflux. Using nonlinear wave propagation theory for distillation...
On the dynamics of the circulation loop reactor : numerical methods and analysis (1995)
Kienle,A., Lauschke,G., Gehrke,V., Gilles,E. D.
The Circulation Loop Reactor has been developed during the last years as an alternative to the well-known switch flow reactor. In contrast to the latter the CLR is intended to work as an autonomous...
Multiple steady states in binary distillation : theoretical and experimental results (1995)
Kienle, A., Groebel, M., Gilles, E. D.
Steady-state multiplicity and instability in distillation is studied theoretically and experimentally for columns with volumetric reflux. Using nonlinear wave propagation theory for distillation...
On the dynamics of the circulation loop reactor : numerical methods and analysis (1995)
Kienle, A., Lauschke, G., Gehrke, V., Gilles, E. D.
The Circulation Loop Reactor has been developed during the last years as an alternative to the well-known switch flow reactor. In contrast to the latter the CLR is intended to work as an autonomous...
Computing multiple steady states in homogeneous azeotropic distillation processes (1994)
Kienle,A., Gilles,E. D., Marquardt,W.
Steady state multiplicity in a single section of a distillation column involving ternary, homogeneous azeotropic mixtures is investigated. Multiple eigenvalues of the equilibrium relation are...
Computing multiple steady states in homogeneous azeotropic distillation processes (1994)
Kienle, A., Gilles, E. D., Marquardt, W.
Steady state multiplicity in a single section of a distillation column involving ternary, homogeneous azeotropic mixtures is investigated. Multiple eigenvalues of the equilibrium relation are...
Tien,D. V., Grüner,S., Kienle,A., Seidel-Morgenstern,A.
Recently we proposed a new approach for analyzing and understanding dynamics and feasibility of combined reaction separation processes (Grüner and Kienle, 2004). The apprach is based on assumption...
Model Based Analysis and Control of an Industrial Molten Carbonate Fuel Cell Stack
Mangold,M., Heidebrecht,P., Gundermann,M., Kienle,A., Sundmacher,K.
Physical Model Development, Model Reduction, and Observer Design of a Molten Carbonate Fuel Cell
Mangold,M., Sheng,M., Heidebrecht,P., Kienle,A., Sundmacher,K.
Kulkarni,A. A., Zeyer,K. P., Jacobs,T., Kienle,A.
A microplant concept is presented for the analysis of homogeneous and heterogeneous acid catalyzed esterification of acetic acid with butanol. The plant configuration includes a micromixer, which...
Kulkarni,A. A., Zeyer,K. P., Jacobs,T., Kienle,A.
A microplant concept is introduced for the analysis of homogeneously and heterogeneously catalyzed liquid phase reactions. Esterification of acetic acid with butanol is considered as a benchmark...
Analysis of Ester Hydrolysis Reactions in a Chromatographic Reactor Using Equilibrium Theory
Kienle,A., Grüner,S., Mai,P. T., Tien,V. D., Seidel-Morgenstern,A.
Tien, D. V., Grüner, S., Kienle, A., Seidel-Morgenstern, A.
Recently we proposed a new approach for analyzing and understanding dynamics and feasibility of combined reaction separation processes (Grüner and Kienle, 2004). The apprach is based on assumption...
Model Based Analysis and Control of an Industrial Molten Carbonate Fuel Cell Stack
Mangold, M., Heidebrecht, P., Gundermann, M., Kienle, A., Sundmacher, K.
Physical Model Development, Model Reduction, and Observer Design of a Molten Carbonate Fuel Cell
Mangold, M., Sheng, M., Heidebrecht, P., Kienle, A., Sundmacher, K.
Analysis of Ester Hydrolysis Reactions in a Chromatographic Reactor Using Equilibrium Theory
Kienle, A., Grüner, S., Mai, P. T., Tien, V. D., Seidel-Morgenstern, A.
Application of the ModiCon-SMB Concept for Variable Purity Requirements
Kaspereit, M., Schramm, H., Lübbert, M., Holz, B., Kienle, A., Seidel-Morgenstern, A.
Simulated Moving Bed (SMB) chromatography has been established as a powerful technology for, e.g., separation of chiral substances or fine chemicals. Although in many applications SMB outperforms...
Impact of Periodically Modified Feed Concentrations on Simulated Moving Bed Processes
Schramm, H., Kaspereit, M., Kienle, A., Seidel-Morgenstern, A.
Thermal effects in reactive chromatography
Sainio, T., Kaspereit, M., Kienle, A., Seidel-Morgenstern, A.
Scale-up of chromatographic columns and reactors processing liquid phases is typically based on increasing the column diameter while maintaining the linear flow velocity constant. Chemical...
Analysis of temperature effects on ester hydrolysis reactions in a fixed-bed chromatographic reactor
Vu, T. D., Mai, P. T., Kienle, A., Seidel-Morgenstern, A.
In order to promote the industrial application of chromatographic reactors there is a need in further systematic studies1. Recently, an approach using simultaneously an extension of the equilibrium...
Kaspereit, M., Sainio, T., Seidel-Morgenstern, A., Kienle, A.
Propagation of concentration fronts (non-linear waves) in chromatographic processes is a result of both kinetic effects and phase equilibrium behavior of the system. However, equilibrium theory [1,...
Design of continuous chromatographic processes under reduced purity requirements
Kaspereit, M., Seidel-Morgenstern, A., Kienle, A.
Continuous chromatographic separations (i. e. SMB processes) are usually designed under the assumption that a binary feed mixture should be separated into two pure fractions. A useful tool in this...
Kaspereit, M., Kulkarni, A. A., Zeyer, K. P., Kienle, A.
One of the most promising approaches for intensification of chemical processes is process integration, i.e. the incorporation of both reaction and separation into a single apparatus. Process...
Nonisothermal Reactive Chromatography
Sainio, T., Zhang, L., Kaspereit, M., Vu, D. T., Mai, T. P., Kienle, A., ...
Selective adsorbents can be used in non-steady state fixed bed reactors to enhance the conversion of reversible reactions through separation of products, which diminishes the undesired backward...
Continuous reactive chromatography under nonisothermal conditions
Sainio, T., Zhang, L., Kaspereit, M., Kienle, A., Seidel-Morgenstern, A.
Reaction and separation can be integrated into a single unit operation in several ways. Selective adsorbents can be used in non-steady state fixed bed reactors to enhance the conversion of reversible...
Production Of Pure Enantiomers By Integrating (Continuous) Chromatography And Racemisation Reactions
Kaspereit, M., Garcia Palacios, J., Meixus Fernandez, T., Sainio, T., Seidel-Morgenstern, A., Kienle, A.
Chemical processes most generally consist of a reaction step and a subsequent separation of the target product from unconverted educts and side products. This holds also for the production of...
Nonlinear Analysis of Cybernetic Models of Biological Systems
Mantravadi, V. K., Kienle, A., Zeyer, K. P., Pushpavanam, S.
Thermal Mass Flow Sensors for Monitoring Esterification Reactions in Residence Time Micro Reactors
Jacobs, T., Kaspereit, M., Zeyer, K. P., Kienle, A., Hauptmann, P.
Theoretical analysis of continuous chromatography with adsorbing additives
Kaspereit, M., Arnell, R., Forssen, P., Seidel-Morgenstern, A., Fornstedt, T., Kienle, A.
Theoretische Analyse zum Einsatz von Additiven in der kontinuierlichen Chromatographie
Kaspereit, M., Arnell, R., Forssen, P., Seidel-Morgenstern, A., Fornstedt, T., Kienle, A.
Thermal Flow Sensor Network for Real-Time Kinetic Analysis of Chemical Reactions in Micro Reactors
Jacobs, T., Kaspereit, M., Zeyer, K. P., Kienle, A., Hauptmann, P.
García Palacios, J., Kaspereit, M., Kienle, A.
A systematic study is performed of integrated processes combining chromatographic separation and isomerisation reactions like, for example, racemisation reactions. In the first part of the study,...
Konzeptionelle Auslegung integrierter chromatographischer Prozesse zur Herstellung von Isomeren
García Palacios, J., Kaspereit, M., Kienle, A.
In dieser Arbeit werden integrierte Prozesse untersucht, die eine chromatographische Trennung mit einer Isomerisierungreaktion kombinieren. Zielstellung ist dabei die Analyse und Auslegung...