Ponchel, F., Verburg, R., Bingham, S., Brown, A., Moore, J., Protheroe, A., ...
We previously demonstrated prolonged, profound CD4+ T-lymphopenia in rheumatoid arthritis (RA) patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de...
Baydoun, A. R., Markham, A., Morgan, R.M., Sweetman, A.J.
Copyright British Pharmacological Society [Full text of this article is not available in the UHRA]
Palmitoyl carnitine: an endogenous promoter of calcium efflux from rat heart mitochondria. (1988)
Baydoun, A. R., Markham, A., Morgan, R.M., Sweetman, A.J.
Original article can be found at: http://www.sciencedirect.com/science/journal/00062952 Copyright Elsevier Inc. DOI: 10.1016/0006-2952(88)90307-3 [Full text of this article is not available in the...
Gillam, S, Atkinson, T, Markham, A, Smith, M
Site-directed mutagenesis has been used to produce a T----A change at nucleotide 70 of phi X174 genome. This generates an am codon, TAG, in the gene K reading frame without affecting the amino acid,...
Wallis, S C, Rogne, S, Gill, L, Markham, A, Edge, M, Woods, D, ...
We have isolated cDNA clones coding for apolipoprotein E (apoE) from a cDNA library prepared from adult human liver mRNA. Mixtures of 128 different oligonucleotides, 17 residues long were synthesised...
Gillam, S, Atkinson, T, Markham, A, Smith, M
Site-directed mutagenesis has been used to produce a T----A change at nucleotide 70 of phi X174 genome. This generates an am codon, TAG, in the gene K reading frame without affecting the amino acid,...
Wallis, S C, Rogne, S, Gill, L, Markham, A, Edge, M, Woods, D, ...
We have isolated cDNA clones coding for apolipoprotein E (apoE) from a cDNA library prepared from adult human liver mRNA. Mixtures of 128 different oligonucleotides, 17 residues long were synthesised...
Overexpression of transcripts containing LINE-1 in the synovia of patients with rheumatoid arthritis
Ali, M, Veale, D, Reece, R, Quinn, M, Henshaw, K, Zanders, E, ...
Methods: Synovial biopsy specimens were obtained by needle arthroscopy from the knees of 10 patients with either RA or ReA. RNA was isolated from the biopsy specimens and cDNA synthesised for...
Expression of the antiapoptosis gene, Survivin, predicts death from recurrent colorectal carcinoma
Sarela, A, Macadam, R, Farmery, S, Markham, A, Guillou, P
BACKGROUND/AIMS—Inhibition of programmed cell death (apoptosis) is associated with increased tumour aggressiveness, and expression of Survivin, an antiapoptosis gene, in colorectal carcinomas may...
The genetics of primary open angle glaucoma
BOOTH, A., CHURCHILL, A., ANWAR, R., MENAGE, M., MARKHAM, A.
Genetic screening in a large family with juvenile onset primary open angle glaucoma
Booth, A., Anwar, R., Chen, H., Churchill, A., Jay, J., Polansky, J., ...
AIMS—A number of genetic loci have been implicated in the pathogenesis of primary open angle glaucoma (POAG). The aim of this study was to identify the genetic cause of POAG in a large Scottish...
Gupta, P., Markham, A., Morgan, R. M.
1. The contractile response of guinea-pig isolated trachealis to KCl has been studied in the presence and absence of cartilage. 2. Dissection of cartilage from the trachealis resulted in both a...
Baydoun, A. R., Markham, A., Morgan, R. M., Sweetman, A. J.
1. The dihydropyridine Ca2+ channel agonist Bay K 8644 (10-200 microM) produced a concentration-dependent increase in State 4 respiration in the rat heart mitochondria with the highest concentration...
Hutchin, T., Parker, M., Young, I., Davis, A., Pulleyn, L., Deeble, J., ...
We describe a family with non-syndromic sensorineural hearing impairment inherited in a manner consistent with maternal transmission. Affected members were found to have a novel heteroplasmic mtDNA...
Marchbank, N, Craig, J, Leek, J, Toohey, M, Churchill, A, Markham, A, ...
Mansur, A, Bishop, D, Holgate, S, Markham, A, Morrison, J
Background: A study was undertaken to validate a locus modulating total serum IgE levels on 14q13–24.